Decoding COVID-19 mRNA Vaccine Immunometabolism in Central Nervous System: human brain normal glial and glioma cells by Raman imaging

The paper presents the effect of COVID-19 mRNA (Pfizer/BioNT) vaccine on in vitro glial cells of the brain studied by means of Raman spectroscopy and imaging.. The results obtained for human brain normal and tumor glial cells of astrocytes, astrocytoma, glioblastoma incubated with the Covid-19 mRNA vaccine Pfizer/BioNT vaccine show alterations in the reduction-oxidation pathways… Continue reading Decoding COVID-19 mRNA Vaccine Immunometabolism in Central Nervous System: human brain normal glial and glioma cells by Raman imaging

Current and future burdens of heat-related hyponatremia – a nationwide register-based study

ContextA seasonal variation in hyponatremia, with higher incidence rates during hot summer days has been demonstrated. Whether this applies to cool temperate regions is currently unknown. ObjectiveThe aim of this study was to investigate the influence of ambient temperature on hyponatremia in the Swedish population under current and future climate scenarios. Design, setting and patientsNationwide… Continue reading Current and future burdens of heat-related hyponatremia – a nationwide register-based study

Artificial sweeteners and cancer risk: Results from the NutriNet-Santé population-based cohort study

The food industry uses artificial sweeteners in a wide range of foods and beverages as alternatives to added sugars, for which deleterious effects on several chronic diseases are now well established. The safety of these food additives is debated, with conflicting findings regarding their role in the aetiology of various diseases. In particular, their carcinogenicity… Continue reading Artificial sweeteners and cancer risk: Results from the NutriNet-Santé population-based cohort study

Why are we vaccinating children against COVID-19?

•Bulk of COVID-19 per capita deaths occur in elderly with high comorbidities. •Per capita COVID-19 deaths are negligible in children. •Clinical trials for these inoculations were very short-term. •Clinical trials did not address long-term effects most relevant to children. •High post-inoculation deaths reported in VAERS (very short-term). AbstractThis article examines issues related to COVID-19 inoculations… Continue reading Why are we vaccinating children against COVID-19?

Abstract 10712: Observational Findings of PULS Cardiac Test Findings for Inflammatory Markers in Patients Receiving mRNA Vaccines

This clinic has been using the PULS Cardiac Test (Predictive Health Diagnostics Co., Irvine, CA) a clinically utilized measurement of multiple protein biomarkers, which generates a score predicting the 5 yr risk (percentage chance) of a new Acute Coronary Syndrome (ACS) called the PULS Score. The score is based on changes from the norm of… Continue reading Abstract 10712: Observational Findings of PULS Cardiac Test Findings for Inflammatory Markers in Patients Receiving mRNA Vaccines

The illusion of evidence based medicine

Evidence based medicine has been corrupted by corporate interests, failed regulation, and commercialisation of academia, argue these authors The advent of evidence based medicine was a paradigm shift intended to provide a solid scientific foundation for medicine. The validity of this new paradigm, however, depends on reliable data from clinical trials, most of which are… Continue reading The illusion of evidence based medicine

Early outpatient treatment for Covid19 with convalescent plasma

Polyclonal convalescent plasma may be obtained from donors who have recovered from coronavirus disease 2019 (Covid-19). The efficacy of this plasma in preventing serious complications in outpatients with recent-onset Covid-19 is uncertain. METHODSIn this multicenter, double-blind, randomized, controlled trial, we evaluated the efficacy and safety of Covid-19 convalescent plasma, as compared with control plasma, in… Continue reading Early outpatient treatment for Covid19 with convalescent plasma

Sex-specific effects of bisphenol A on the signaling pathway of ESRRG in the human placenta

AbstractBisphenol A (BPA) exposure during pregnancy is associated with low fetal weight, particularly in male fetuses. The expression of estrogen-related receptor gamma (ESRRG), a receptor for BPA in the human placenta, is reduced in fetal growth restriction. This study sought to explore whether ESRRG signaling mediates BPA-induced placental dysfunction and determine whether changes in the… Continue reading Sex-specific effects of bisphenol A on the signaling pathway of ESRRG in the human placenta

A Comparative Analysis of COVID-19 Vaccines Based on over 580,000 Cases from the Vaccination Adverse Event Reporting System

Background: The COVID-19 pandemic is being battled via the largest vaccination campaign in history, with more than eight billion doses administered thus far. Therefore, discussions about potentially adverse reactions, and broader safety concerns, are critical. The U.S. Vaccination Adverse Event Reporting System (VAERS) has recorded vaccination side effects for over 30 years. About 580,000 events… Continue reading A Comparative Analysis of COVID-19 Vaccines Based on over 580,000 Cases from the Vaccination Adverse Event Reporting System