Objective: This study aims to compare the short-term clinical outcomes of one-stage and two-stage revision surgeries for treating chronic periprosthetic joint infection (#PJI ), addressing the limitations of the prolonged treatment cycle and heavy medical burden associated with two-stage revision, and evaluating the feasibility and effectiveness of one-stage revision as an alternative therapeutic strategy.Methods: This… Continue reading Reevaluation of surgical strategies for chronic periprosthetic joint infection: a comparison of short-term outcomes between one-stage and two-stage revision
Category: Orthopedy
The Effects of Disease-Modifying Anti-Rheumatic Drugs on Total Hip #Arthroplasty Outcomes in Patients Who Have Inflammatory Arthropathies
Introduction: Disease-modifying anti-rheumatic drugs (#DMARDs ) are essential in managing inflammatory arthritides such as #rheumatoid arthritis (RA), psoriatic #arthritis (PsA), and juvenile idiopathic arthritis (JIA). As total hip arthroplasty (THA) and DMARD use become more common, it is unclear how DMARD use affects outcomes in this population. This study compared complications and implant survivorship after… Continue reading The Effects of Disease-Modifying Anti-Rheumatic Drugs on Total Hip #Arthroplasty Outcomes in Patients Who Have Inflammatory Arthropathies
Evaluating the Effects of Perioperative Ketorolac Use on Outcomes After Surgical Treatment of Open Reduction and Internal Fixation of Ankle Fractures
Background: #Ketorolac is commonly used as part of multimodal analgesia after #orthopaedic surgery; however, concerns persist regarding its potential effects on postoperative #wound healing and fracture union. While previous studies have evaluated ketorolac use in arthroplasty and long bone fractures, data specific to ankle open reduction and internal fixation (#ORIF ) remain limited. This study… Continue reading Evaluating the Effects of Perioperative Ketorolac Use on Outcomes After Surgical Treatment of Open Reduction and Internal Fixation of Ankle Fractures
Behavioral Incentives for Exercise and Intra-Articular Corticosteroids for Knee Osteoarthritis: Results from a Factorially Designed Pragmatic Randomized Clinical Trial
Purpose: To determine the benefit of a behaviorally-designed incentive program and corticosteroid injections in reducing symptoms and promoting physical activity in patients with knee #osteoarthritis (KOA).Methods: This was a pragmatic, multi-site, factorially-designed, blinded, randomized clinical trial. Participants with a clinical diagnosis of KOA and an indication for joint injection (age 40-85 years; Kellgren-Lawrence X-ray grade… Continue reading Behavioral Incentives for Exercise and Intra-Articular Corticosteroids for Knee Osteoarthritis: Results from a Factorially Designed Pragmatic Randomized Clinical Trial
Electroacupuncture alleviates acute gouty arthritis by inhibiting NLRP3 inflammasome activation via modulation of the circadian-inflammation axis
Electroacupuncture (#EA ) has shown anti-inflammatory potential in #gouty #arthritis (GA). This study aimed to investigate its therapeutic effects and underlying mechanisms. Core acupoints (ST36 and SP6) were identified through data-mining. In MSU-induced GA rats, EA significantly alleviated joint swelling, improved gait, reduced serum TNF-α, IL-6 and IL-1β, and suppressed synovial inflammatory infiltration. Mechanistically, EA… Continue reading Electroacupuncture alleviates acute gouty arthritis by inhibiting NLRP3 inflammasome activation via modulation of the circadian-inflammation axis
Efficacy of electroacupuncture for pain relief in patients with osteonecrosis of the femoral head: protocol for a randomised, triple-blind, sham-controlled trial
Introduction #Osteonecrosis of the femoral head (ONFH) is a progressive and disabling condition, with pain being its predominant symptom. #Electroacupuncture (EA) has shown promise in the management of chronic pain; however, high-quality evidence on its efficacy and safety in ONFH is still lacking. The aim of this trial is to evaluate the efficacy and safety… Continue reading Efficacy of electroacupuncture for pain relief in patients with osteonecrosis of the femoral head: protocol for a randomised, triple-blind, sham-controlled trial
Pro-inflammatory dietary patterns are associated with increased pain and functional disability in sciatica: a hospital-based cross-sectional study
Background: #Sciatica is a common neuropathic pain condition associated with substantial functional disability. Emerging evidence suggests that #diet -induced inflammation may play a role in chronic pain development. However, the association between dietary inflammatory potential and clinical outcomes in sciatica remains unclear.Methods: In this cross-sectional study, we enrolled 598 patients diagnosed with sciatica from two… Continue reading Pro-inflammatory dietary patterns are associated with increased pain and functional disability in sciatica: a hospital-based cross-sectional study
Effects of Acupuncture on Time-Dependent Muscle Endurance in Men with Post-Anterior Cruciate Ligament Injury: A Randomized Controlled Crossover Trial
To investigate whether acupuncture enhances knee joint muscle endurance effectiveness and time-dependent effects after anterior cruciate ligament ( #ACL ) injuries.Methods:This randomized, single-blinded crossover trial included 20 males with ACL injuries. Participants were randomly divided into real acupuncture (RA) group and sham acupuncture (SA) group. RA was stimulated at ST32, ST34, ST36, SP10, and BL57;… Continue reading Effects of Acupuncture on Time-Dependent Muscle Endurance in Men with Post-Anterior Cruciate Ligament Injury: A Randomized Controlled Crossover Trial
Effectiveness of Non-Pharmacological Interventions for Hormone Therapy-Induced #Hand #Arthralgia in Breast Cancer Patients: A Systematic Review
BackgroundAromatase inhibitor-induced arthralgia (AIA) is a frequent adverse effect of endocrine therapy in breast cancer survivors, often leading to treatment modification or discontinuation. Non-pharmacological interventions have been proposed to manage AIA, but evidence remains fragmented.ObjectiveTo synthesize recent randomized controlled trials (RCTs) evaluating the efficacy of non-pharmacological interventions for AIA.MethodsA systematic search of PubMed, Scopus, and… Continue reading Effectiveness of Non-Pharmacological Interventions for Hormone Therapy-Induced #Hand #Arthralgia in Breast Cancer Patients: A Systematic Review
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