Brain Structure in Acutely Underweight and Partially Weight-Restored Individuals with Anorexia Nervosa – A Coordinated Analysis by the ENIGMA Eating Disorders Working Group

BackgroundThe pattern of structural brain abnormalities in anorexia nervosa (AN) is still not well understood. While several studies report substantial deficits in grey matter volume and cortical thickness in acutely underweight patients, others find no differences, or even increases in patients compared with healthy controls. Recent weight regain before scanning may explain some of this …

Continue reading Brain Structure in Acutely Underweight and Partially Weight-Restored Individuals with Anorexia Nervosa – A Coordinated Analysis by the ENIGMA Eating Disorders Working Group

#Mirtazapine in cancer-associated #anorexia and #cachexia: A double-blind placebo-controlled randomized trial

Few pharmacological interventions are available for cancer-associated anorexia and cachexia. Mirtazapine has been suggested for use in cancer-associated anorexia and cachexia. ObjectivesThis study was conducted to assess the efficacy and tolerability of mirtazapine in cancer-associated anorexia and cachexia. MethodsA double-blind placebo-controlled randomized trial. The study included 120 incurable solid tumour patients with anorexia (appetite loss …

Continue reading #Mirtazapine in cancer-associated #anorexia and #cachexia: A double-blind placebo-controlled randomized trial