Midlife lipid and glucose levels are associated with Alzheimer’s disease

IntroductionIt is unknown whether vascular and metabolic diseases assessed in early adulthood are associated with Alzheimer's disease (AD) later in life. MethodsAssociation of AD with lipid fractions, glucose, blood pressure, body mass index (BMI), and smoking obtained prospectively from 4932 Framingham Heart Study (FHS) participants across nine quadrennial examinations was evaluated using Cox proportional hazard… Continue reading Midlife lipid and glucose levels are associated with Alzheimer’s disease

Stroke Associated with COVID-19 Vaccines

Development of safe and effective vaccines against coronavirus disease 2019 (COVID-19) remains the cornerstone of controlling this pandemic. However, there are increasing reports of various types of stroke including ischemic stroke, and hemorrhagic stroke, as well as cerebral venous sinus thrombosis (CVST) after COVID-19 vaccination. This paper aims to review reports of stroke associated with… Continue reading Stroke Associated with COVID-19 Vaccines

The Association of Consumption Time for Food With Cardiovascular Disease and All-Cause Mortality Among Diabetic Patients

AimsThis study aims to investigate whether food intake time across 3 meals is associated with long-term survival among the people with diabetes. Materials and MethodsThis study included 4642 diabetic patients participating in the National Health and Nutrition Examination Survey from 2003 to 2014. Food consumed across a day including the forenoon, afternoon, and evening was… Continue reading The Association of Consumption Time for Food With Cardiovascular Disease and All-Cause Mortality Among Diabetic Patients

Cerebral venous thrombosis after vaccination against COVID-19 in the UK: a multicentre cohort study

BackgroundA new syndrome of vaccine-induced immune thrombotic thrombocytopenia (VITT) has emerged as a rare side-effect of vaccination against COVID-19. Cerebral venous thrombosis is the most common manifestation of this syndrome but, to our knowledge, has not previously been described in detail. We aimed to document the features of post-vaccination cerebral venous thrombosis with and without… Continue reading Cerebral venous thrombosis after vaccination against COVID-19 in the UK: a multicentre cohort study

1186-021 / 21 – REGULAR COFFEE INTAKE IS ASSOCIATED WITH IMPROVED MORTALITY IN PREVALENT CARDIOVASCULAR DISEASE

Historically physicians recommend avoiding coffee in patients with arrhythmia and cardiovascular disease (CVD). However, data is lacking on safety of coffee in those with prevalent arrhythmia/CVD. We sought to investigate the associations between coffee and mortality/arrhythmia outcomes in prevalent conditionsMethods: The UK Biobank consists of 502543 people followed over > 10years. Self-reported coffee intake was divided… Continue reading 1186-021 / 21 – REGULAR COFFEE INTAKE IS ASSOCIATED WITH IMPROVED MORTALITY IN PREVALENT CARDIOVASCULAR DISEASE

1052-05 – GROUND, INSTANT, OR DECAFFEINATED COFFEE? IMPACT OF DIFFERENT COFFEE SUBTYPES ON INCIDENT ARRHYTHMIA, CARDIOVASCULAR DISEASE AND MORTALITY

Background: Population studies report health benefits from coffee intake. Coffee has up to 100 biologic compounds with caffeine most well known. The effects of coffee subtypes on cardiovascular(CV) outcomes is unclear. We aim to evaluate the associations between coffee subtypes and incident arrhythmia, CV disease (CVD), and total/ CV mortalityMethods: Participant responses to coffee amount and type(ground,… Continue reading 1052-05 – GROUND, INSTANT, OR DECAFFEINATED COFFEE? IMPACT OF DIFFERENT COFFEE SUBTYPES ON INCIDENT ARRHYTHMIA, CARDIOVASCULAR DISEASE AND MORTALITY

Association of midlife antibiotic use with subsequent cognitive function in women

The gut microbiome is increasingly recognized to play a role in cognition and dementia. Antibiotic use impacts the gut microbiome and has been linked with chronic disease. Despite these data, there is no evidence supporting an association between long-term antibiotic use in adults and cognitive function. We conducted a prospective population-based cohort study among 14,542… Continue reading Association of midlife antibiotic use with subsequent cognitive function in women

1056-05 – EFFECTS OF HABITUAL COFFEE CONSUMPTION ON INCIDENT CARDIOVASCULAR DISEASE, ARRHYTHMIA, AND MORTALITY: FINDINGS FROM UK BIOBANK

Background: Meta analyses report beneficial effects of coffee intake on incident cardiovascular outcomes, however earlier studies are limited by smaller sample sizes. The aim was to evaluate associations between coffee intake and incident arrhythmia, CVD, and mortality, utilising the UK BiobankMethods: The UK Biobank is a large prospective cohort with outcomes measured >10 years. Coffee… Continue reading 1056-05 – EFFECTS OF HABITUAL COFFEE CONSUMPTION ON INCIDENT CARDIOVASCULAR DISEASE, ARRHYTHMIA, AND MORTALITY: FINDINGS FROM UK BIOBANK

Association between lithium use and the incidence of dementia and its subtypes: A retrospective cohort study

BackgroundDementia is the leading cause of death in elderly Western populations. Preventative interventions that could delay dementia onset even modestly would provide a major public health impact. There are no disease-modifying treatments currently available. Lithium has been proposed as a potential treatment. We assessed the association between lithium use and the incidence of dementia and… Continue reading Association between lithium use and the incidence of dementia and its subtypes: A retrospective cohort study