I’ve been receiving an escalating stream of panicked emails from people telling me their longtime physician was retiring, was no longer taking their insurance, or had gone concierge and would no longer see them unless they ponied up a hefty annual fee. They have said they couldn’t find another primary care doctor who could take… Continue reading The Shrinking Number of Primary Care Physicians Is Reaching a Tipping Point
Author: aledopress
Medicine and Technology enthusiast..
The Gut-Brain Axis: Unveiling the Microbiome’s Role in Cognitive Development and Brain Health
A Complex Communication Highway In the intricate network of the human body, a fascinating unsuspected connection is being unraveled—one that links the gut and the brain in ways we never imagined! This connection, known as the Gut-Brain Axis, is revealing a whole new dimension to the critical role played by the microbiome in the development… Continue reading The Gut-Brain Axis: Unveiling the Microbiome’s Role in Cognitive Development and Brain Health
Effect of apolipoprotein genotype and #educational attainment on #cognitive function in autosomal dominant #Alzheimer’s disease
Autosomal dominant Alzheimer’s disease (ADAD) is genetically determined, but variability in age of symptom onset suggests additional factors may influence cognitive trajectories. Although apolipoprotein E (APOE) genotype and educational attainment both influence dementia onset in sporadic AD, evidence for these effects in ADAD is limited. To investigate the effects of APOE and educational attainment on age-related cognitive… Continue reading Effect of apolipoprotein genotype and #educational attainment on #cognitive function in autosomal dominant #Alzheimer’s disease
Resistant #starch decreases intrahepatic #triglycerides in patients with #NAFLD via gut microbiome alterations
Non-alcoholic fatty liver disease (NAFLD) is a hepatic manifestation of metabolic dysfunction for which effective interventions are lacking. To investigate the effects of resistant starch (RS) as a microbiota-directed dietary supplement for NAFLD treatment, we coupled a 4-month randomized placebo-controlled clinical trial in individuals with NAFLD (ChiCTR-IOR-15007519) with metagenomics and metabolomics analysis. Relative to the… Continue reading Resistant #starch decreases intrahepatic #triglycerides in patients with #NAFLD via gut microbiome alterations
Association of Later-Life #Weight Changes With #Survival to Ages 90, 95, and 100: The Women’s Health Initiative
BackgroundAssociations of weight changes and intentionality of weight loss with longevity are not well described.MethodsUsing longitudinal data from the Women’s Health Initiative (N = 54 437; 61–81 years), we examined associations of weight changes and intentionality of weight loss with survival to ages 90, 95, and 100. Weight was measured at baseline, year 3, and year 10,… Continue reading Association of Later-Life #Weight Changes With #Survival to Ages 90, 95, and 100: The Women’s Health Initiative
Warning symptoms associated with imminent sudden #cardiac arrest: a population-based case-control study with external validation
BackgroundSudden cardiac arrest is a global public health problem with a mortality rate of more than 90%. Prearrest warning symptoms could be harnessed using digital technology to potentially improve survival outcomes. We aimed to estimate the strength of association between symptoms and imminent sudden cardiac arrest.MethodsWe conducted a case-control study of individuals with sudden cardiac… Continue reading Warning symptoms associated with imminent sudden #cardiac arrest: a population-based case-control study with external validation
High #ultra-processed food consumption is associated with elevated #psychological distress as an indicator of #depression in adults from the Melbourne Collaborative Cohort Study
Highlights•Participants with the highest intake of ultra-processed food had increased odds of elevated psychological distress•We found no evidence for an interaction of sex, age and body mass index with ultra-processed food intake•Further research is needed to better inform nutrition-related and public health strategies for mental health BackgroundFew studies have tested longitudinal associations between ultra-processed food… Continue reading High #ultra-processed food consumption is associated with elevated #psychological distress as an indicator of #depression in adults from the Melbourne Collaborative Cohort Study
Effects of adult #education on #cognitive function and risk of #dementia in older adults: a longitudinal analysis
Introduction: Mid/late-life cognitive activities are associated with a lower rate of subsequent cognitive decline and lower subsequent dementia risk over time.Methods: In this study, we investigated the association between adult education class participation and subsequent cognitive decline and dementia risk over time after adjusting for baseline cognitive function and genetic risk of dementia, correcting for several potential… Continue reading Effects of adult #education on #cognitive function and risk of #dementia in older adults: a longitudinal analysis
Effect of Vitamin #D Supplements on Relapse or Death in a p53-Immunoreactive Subgroup With #Digestive Tract Cancer
Recent meta-analyses of randomized clinical trials found that daily vitamin D3 supplementation had beneficial effects on cancer mortality, although the results are still controversial.Objective To examine whether vitamin D supplementation reduces the risk of relapse or death in a supgroup of patients with digestive tract cancer who were p53 immunoreactive.Design, Setting, and Participants This was a post… Continue reading Effect of Vitamin #D Supplements on Relapse or Death in a p53-Immunoreactive Subgroup With #Digestive Tract Cancer
2 Medical News 