Global health outcomes from replacing dietary sodium chloride with potassium-enriched salt

Potassium-enriched salt is a practical, low-cost population-level intervention for preventing non-communicable diseases. Here we modelled the health effects of replacing regular salt with potassium-enriched salt under five scenarios using comparative risk assessment: (1) replacement of all added salt; (2) replacement of discretionary salt used in home cooking and seasoning; (3) replacement of non-discretionary salt used… Continue reading Global health outcomes from replacing dietary sodium chloride with potassium-enriched salt

Development and Validation of a Machine Learning Model for Predicting Three-Month Unplanned Readmission in Patients with Moderate-to-Severe Chronic Obstructive Pulmonary Disease: A Retrospective Cohort Study

Purpose: Patients with moderate-to-severe chronic obstructive pulmonary disease (COPD) face a high risk of three-month unplanned readmission after discharge, yet early identification of high-risk patients remains challenging in clinical practice. This study aimed to develop and validate machine learning (ML) models for predicting the risk and providing a reference for the subsequent development and updating… Continue reading Development and Validation of a Machine Learning Model for Predicting Three-Month Unplanned Readmission in Patients with Moderate-to-Severe Chronic Obstructive Pulmonary Disease: A Retrospective Cohort Study

Oral vs parenteral drug administration: Quantifying the future health costs of routine prescribing choices through their environmental scope

Background: Climate change is a major threat to global health, and healthcare is itself a substantial contributor. Choosing the route of drug administration may represent a simple opportunity to reduce environmental impact without compromising care.Objective: To quantify and compare the incremental environmental impacts and projected future health losses associated with oral, intravenous (IV), and intramuscular… Continue reading Oral vs parenteral drug administration: Quantifying the future health costs of routine prescribing choices through their environmental scope

Sicker at all ages? Two decades of changing disease histories and mortality in the United States

Background: Stagnating cardiovascular disease mortality and rising drug- and suicide-related deaths are key drivers of stalled US mortality improvements. However, prior research has largely overlooked disease histories preceding death, despite increasing multimorbidity. We examined changes in disease-history profiles in the US population and assessed how shifts in profile composition and within-profile mortality shaped mortality trends.Methods:… Continue reading Sicker at all ages? Two decades of changing disease histories and mortality in the United States

Evaluation of Nurses’ Intent to Leave: Italian Translation, Cultural Adaptation, and Initial Psychometric Assessment of the Anticipated Turnover Scale

Aim: The aim of this study was to translate, culturally adapt, and preliminarily validate the Italian version of the Anticipated Turnover Scale (ATS).Design: Cross-sectional validation study.Methods: The Italian version of the ATS instrument was evaluated in a non-probabilistic sample of 168 nurses working at a Northeastern Italian Public University Hospital. Content validity was assessed by… Continue reading Evaluation of Nurses’ Intent to Leave: Italian Translation, Cultural Adaptation, and Initial Psychometric Assessment of the Anticipated Turnover Scale

“Hospital-at-home and 30-day readmission among clinically eligible patients: a prospective cohort study with a capacity-constrained comparator group

Background and aims: To evaluate the association between hospital-at-home (HaH) care and unplanned 30-day hospital readmission using a capacity-based comparator group of clinically eligible patients admitted to conventional hospitalization (CH) because of lack of HaH capacity.Methods: This prospective observational study was conducted between 2023 and 2026 at a tertiary hospital in Spain. A total of… Continue reading “Hospital-at-home and 30-day readmission among clinically eligible patients: a prospective cohort study with a capacity-constrained comparator group

“Missing the forest for the trees” Is there any crisis of vocation for Emergency Medicine in Italy?

In recent years, several stakeholders in Italy have suggested a crisis of vocation for Emergency Medicine (EM). This study aimed to verify the accuracy of such claims. We conducted an observational cross-sectional study on data from the Italian national test for residency positions assignments from 2019 to 2025. We analyzed trends in the number of… Continue reading “Missing the forest for the trees” Is there any crisis of vocation for Emergency Medicine in Italy?

Bridging the Gap: Using an Asynchronous E-Learning Module to Improve Internal Medicine Residents’ Confidence and Preparedness in Ambulatory Blood Pressure Monitoring Interpretation

Background: Ambulatory blood #pressure monitoring (ABPM) is considered a reference standard for diagnosing #hypertension and is recommended for out-of-office blood pressure assessment, yet internal medicine residents receive limited training in its interpretation. We conducted a needs assessment to identify gaps in hypertension and ABPM education and developed an asynchronous e-learning module to address these deficiencies.… Continue reading Bridging the Gap: Using an Asynchronous E-Learning Module to Improve Internal Medicine Residents’ Confidence and Preparedness in Ambulatory Blood Pressure Monitoring Interpretation

Evaluation of albumin utilization, guideline compliance, and cost in intensive care units: a multicenter point prevalence study

Background: Intravenous (IV) #albumin is widely used in intensive care units (#ICUs ), yet its use often deviates from evidence-based recommendations, leading to unnecessary costs. This study evaluates the indications for the use of IV albumin in critically ill patients, compliance with the 2024 "Use of Intravenous Albumin" guidelines, and the associated cost burden.Methods: A… Continue reading Evaluation of albumin utilization, guideline compliance, and cost in intensive care units: a multicenter point prevalence study