Patients undergoing total hip replacement (THR) and total knee replacement (TKR) receive venous thromboembolism (VTE) pharmacoprophylaxis. It is unclear which anticoagulant is preferable. Observational data suggest aspirin provides effective VTE prophylaxis.. ..The RR of VTE after THR and TKR was 1.12 (95% CI, 0.78-1.62) for aspirin compared with other anticoagulants. Comparable findings were observed for… Continue reading Clinical Effectiveness and Safety of #Aspirin for Venous #Thromboembolism Prophylaxis After Total Hip and Knee Replacement
#Periodontitis increases the risk of respiratory disease mortality in older patients
Evidence for an association between periodontitis and respiratory disease in the older patients is limited.. ..We found that periodontitis was associated with total respiratory disease mortality. Compared with healthy participants, the hazards ratio and 95% confidence interval for total respiratory disease mortality in patients with severe periodontitis was 2.72(1.04,7.11) after adjusting for relevant confounding variables.… Continue reading #Periodontitis increases the risk of respiratory disease mortality in older patients
Olive Oil Consumption and Cardiovascular Risk in U.S. Adults
Olive oil intake has been associated with lower risk of cardiovascular disease (CVD) in Mediterranean populations, but little is known about these associations in the U.S population. ..During 24 years of follow-up, we documented 9,797 incident cases of CVD, including 6,034 CHD cases and 3,802 stroke cases. After adjusting for major diet and lifestyle factors,… Continue reading Olive Oil Consumption and Cardiovascular Risk in U.S. Adults
Human transport of thirdhand tobacco #smoke: A prominent source of hazardous air pollutants into indoor nonsmoking environments
The contamination of indoor nonsmoking environments with thirdhand smoke (THS) is an important, poorly understood public health concern. Real-time THS off-gassing from smokers into a nonsmoking movie theater was observed with online and offline high-resolution mass spectrometry. Prominent emission events of THS tracers (e.g., 2,5-dimethylfuran, 2-methylfuran, and acetonitrile) and other tobacco-related volatile organic compounds (VOCs)… Continue reading Human transport of thirdhand tobacco #smoke: A prominent source of hazardous air pollutants into indoor nonsmoking environments
Nutritional Factors, Physical Health and Immigrant Status Are Associated with Anxiety Disorders among Middle-Aged and Older Adults: Findings from Baseline Data of The Canadian Longitudinal Study on Aging (CLSA)
..Of 26,991 participants (49.3% men, 82.5% Canadian born, 58.5% aged 45–65 years), the overall prevalence of self-reported physician diagnosis of anxiety disorders was 8.5%, with immigrants being lower than Canadian-born respondents (6.4% vs. 9.3%, p < 0.001). After accounting for all covariates, the adjusted odds ratio (aOR) for anxiety disorders was lower among immigrants (aOR… Continue reading Nutritional Factors, Physical Health and Immigrant Status Are Associated with Anxiety Disorders among Middle-Aged and Older Adults: Findings from Baseline Data of The Canadian Longitudinal Study on Aging (CLSA)
#Beverage Consumption and Longitudinal Changes in Lipoprotein Concentrations and Incident #Dyslipidemia in US Adults: The Framingham Heart Study
Limited data are available on the prospective relationship between beverage consumption and plasma lipid and lipoprotein concentrations. Two major sources of sugar in the US diet are sugar‐sweetened beverages (SSBs) and 100% fruit juices. Low‐calorie sweetened beverages are common replacements.. ..We found that regular (>1 serving per day) versus low (<1 serving per month) SSB… Continue reading #Beverage Consumption and Longitudinal Changes in Lipoprotein Concentrations and Incident #Dyslipidemia in US Adults: The Framingham Heart Study
Practice guideline: Treatment for insomnia and disrupted sleep behavior in children and adolescents with autism spectrum disorder
Major recommendations (Level B) For children and adolescents with ASD and sleep disturbance, clinicians should assess for medications and coexisting conditions that could contribute to the sleep disturbance and should address identified issues. Clinicians should counsel parents regarding strategies for improved sleep habits with behavioral strategies as a first-line treatment approach for sleep disturbance either… Continue reading Practice guideline: Treatment for insomnia and disrupted sleep behavior in children and adolescents with autism spectrum disorder
Total #Sitting Time and Sitting Pattern in Postmenopausal Women Differ by Hispanic Ethnicity and are Associated With #Cardiometabolic Risk Biomarkers
Sedentary behavior is pervasive, especially in older adults, and is associated with cardiometabolic disease and mortality. Relationships between cardiometabolic biomarkers and sitting time are unexplored in older women, as are possible ethnic differences.. ..Hispanic women sat, on average, 50.3 minutes less/day than non‐Hispanic women (P<0.001) and had shorter (3.6 minutes less, P=0.02) mean sitting bout… Continue reading Total #Sitting Time and Sitting Pattern in Postmenopausal Women Differ by Hispanic Ethnicity and are Associated With #Cardiometabolic Risk Biomarkers
Evaluation of a Common Prescribing Cascade of Calcium Channel Blockers and Diuretics in Older Adults With #Hypertension
Calcium channel blockers (CCBs) are commonly prescribed agents for hypertension that can cause peripheral edema. A prescribing cascade occurs when the edema is misinterpreted as a new medical condition and a diuretic is subsequently prescribed to treat the edema. The extent to which this prescribing cascade occurs at a population level is not well understood..… Continue reading Evaluation of a Common Prescribing Cascade of Calcium Channel Blockers and Diuretics in Older Adults With #Hypertension
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