FDA is warning that use of NSAIDs around 20 weeks or later in pregnancy may cause rare but serious kidney problems in an unborn baby. This can lead to low levels of amniotic fluid surrounding the baby and possible complications. For prescription NSAIDs, FDA is requiring changes to the prescribing information to describe the risk… Continue reading Nonsteroidal Anti-Inflammatory Drugs (#NSAIDs): Drug Safety Communication – Avoid Use of NSAIDs in #Pregnancy at 20 Weeks or Later
Effect of #Tocilizumab vs Standard Care on Clinical Worsening in Patients Hospitalized With #COVID-19 Pneumonia
The coronavirus disease 2019 (COVID-19) pandemic is threatening billions of people worldwide. Tocilizumab has shown promising results in retrospective studies in patients with COVID-19 pneumonia with a good safety profile.. ..Patients in the experimental arm received intravenous tocilizumab within 8 hours from randomization (8 mg/kg up to a maximum of 800 mg), followed by a… Continue reading Effect of #Tocilizumab vs Standard Care on Clinical Worsening in Patients Hospitalized With #COVID-19 Pneumonia
#Hypoalbuminemia is associated with increased risk of acute #kidney injury in hospitalized patients: A meta-analysis
Highlights • Each 1.0 g/dL of serum albumin decrement was associated with increased odds of AKI (OR 1.685; 95% CI, 1.302–2.179). • The risk factors for AKI in hypoalbuminemic patients include 1) age ≥ 70 years and 2) baseline serum albumin level > 3.2 g/dL. • The association between hypoalbuminemia and overall mortality from AKI remained inconclusive as there was potential publication… Continue reading #Hypoalbuminemia is associated with increased risk of acute #kidney injury in hospitalized patients: A meta-analysis
Additive effects of green #tea and #coffee on all-cause mortality in patients with type 2 #diabetes mellitus: the Fukuoka Diabetes Registry
The impact of consuming green tea or coffee on mortality in patients with diabetes is controversial. We prospectively investigated the impact of each beverage and their combination on mortality among Japanese patients with type 2 diabetes.. ..During the follow-up period, 309 participants died. The consumption of green tea, coffee, and a combination of the beverages… Continue reading Additive effects of green #tea and #coffee on all-cause mortality in patients with type 2 #diabetes mellitus: the Fukuoka Diabetes Registry
Linked Color Imaging Focused on Neoplasm Detection in the Upper Gastrointestinal Tract
Linked color imaging (LCI) is a new image-enhanced endoscopy technique that allows users to recognize slight differences in mucosal color To compare the performance of LCI with white light imaging (WLI) in detecting neoplastic lesions in the upper gastrointestinal tract.. ..752 patients were assigned to the WLI group and 750 to the LCI group. The… Continue reading Linked Color Imaging Focused on Neoplasm Detection in the Upper Gastrointestinal Tract
Effect of time of day of recreational and household #physical activity on prostate and breast #cancer risk (MCC‐Spain study)
Experimental evidence indicates that exercise performed at different times of the day may affect circadian rhythms and circadian disruption has been linked to breast and prostate cancer. We examined in a population‐based case‐control study (MCC‐Spain) if the time‐of‐day when physical activity is done affects prostate and breast cancer risk. Lifetime recreational and household physical activity… Continue reading Effect of time of day of recreational and household #physical activity on prostate and breast #cancer risk (MCC‐Spain study)
644 – Development of noninvasive #diabetes monitoring method using #tear samples
To prevent diabetic complications, strict glucose control and frequent monitoring of blood glucose levels are necessary. However, all currently available methods for blood glucose monitoring, including the finger prick method, are invasive. Therefore, noninvasive blood glucose monitoring approaches have been investigated, but until date, none has been found to be a suitable substitute for direct… Continue reading 644 – Development of noninvasive #diabetes monitoring method using #tear samples
Effectiveness of pelvic floor #muscle training with and without electromyographic biofeedback for urinary #incontinence in women: multicentre randomised controlled trial
To assess the effectiveness of pelvic floor muscle training (PFMT) plus electromyographic biofeedback or PFMT alone for stress or mixed urinary incontinence in women.. Mean ICIQ-UI SF scores at 24 months were 8.2 (SD 5.1, n=225) in the biofeedback PFMT group and 8.5 (SD 4.9, n=235) in the PFMT group (mean difference −0.09, 95% confidence… Continue reading Effectiveness of pelvic floor #muscle training with and without electromyographic biofeedback for urinary #incontinence in women: multicentre randomised controlled trial
Association of postoperative #influenza vaccine on overall mortality in patients undergoing curative surgery for solid #tumors
Recent findings have found that the influenza vaccine induces changes in the immune system in favor of anti‐tumor cytotoxicity. The aim in this study was to investigate if an influenza vaccine given in the postoperative period decreased overall and cancer‐specific mortality in patients undergoing curative surgery for solid cancers. We conducted a registry‐based national observational… Continue reading Association of postoperative #influenza vaccine on overall mortality in patients undergoing curative surgery for solid #tumors
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