There has been increasing public concern that COVID-19 vaccines cause menstrual cycle disturbances, yet there is currently limited data to evaluate the impact of vaccination on menstrual health. Our objectives were (1) to evaluate the prevalence of menstrual changes following vaccination against COVID-19, (2) to test potential risk factors for any such changes, and (3)… Continue reading COVID-19 vaccination and menstrual cycle changes: A United Kingdom (UK) retrospective case-control study
Category: Gynaecology
Effect of pharmacological interventions on lipid profiles and C-reactive protein in polycystic ovary syndrome: A systematic review and meta-analysis
Polycystic ovary syndrome (PCOS) is a heterogeneous condition affecting women of reproductive age. It is associated with dyslipidaemia and elevated plasma C-reactive protein (CRP), which increase the risks of cardiovascular disease (CVD). ObjectiveTo review the existing evidence on the effects of different pharmacological interventions on lipid profiles and CRP of women with PCOS. Data SourcesWe… Continue reading Effect of pharmacological interventions on lipid profiles and C-reactive protein in polycystic ovary syndrome: A systematic review and meta-analysis
#Nut consumption in association with overall mortality and recurrence/disease-specific mortality among long-term breast #cancer survivors
High nut consumption is associated with reduced total and certain cause-specific mortality in general populations. However, its association with cancer outcomes among long-term breast cancer survivors remains unknown. We examined the associations of nut consumption (including peanuts and tree nuts), assessed at 5-year postdiagnosis, with overall survival (OS) and disease-free survival (DFS) among 3449 long-term… Continue reading #Nut consumption in association with overall mortality and recurrence/disease-specific mortality among long-term breast #cancer survivors
Age-related changes in #bone density, microarchitecture and strength in postmenopausal Black and White women: SWAN Longitudinal HR-pQCT Study
Higher fracture risk in White versus Black women is partly explained by lower BMD and worse bone microarchitecture in White women. However, whether rates of decline in bone density, microarchitecture and strength differ between postmenopausal Black and White women is unknown. Further, factors that influence rates of age-related bone microarchitecture deterioration remain ill-defined. Thus, over… Continue reading Age-related changes in #bone density, microarchitecture and strength in postmenopausal Black and White women: SWAN Longitudinal HR-pQCT Study
Effect of #Zuranolone vs Placebo in Postpartum #DepressionA Randomized Clinical Trial
Postpartum depression (PPD) is one of the most common medicalcomplications during and after pregnancy, negatively affecting both mother and child.OBJECTIVE To demonstrate the efficacy and safety of zuranolone, a neuroactive steroidγ-aminobutyric acid receptor–positive allosteric modulator, in PPD. DESIGN, SETTING, AND PARTICIPANTS This phase 3, double-blind, randomized, outpatient,placebo-controlled clinical trial was conducted between January 2017 and… Continue reading Effect of #Zuranolone vs Placebo in Postpartum #DepressionA Randomized Clinical Trial
The associations between prenatal #cannabis use disorder and neonatal outcomes
Background and AimsCannabis use disorder (CUD) during pregnancy has increased dramatically in the United States (US). This study examined the associations between prenatal CUD and adverse neonatal outcomes and heterogeneities in the associations by mothers’ tobacco use status and race/ethnicity. DesignPopulation-based, retrospective cohort study. SettingCalifornia, USA. ParticipantsA total of 4.83 million mothers who delivered a… Continue reading The associations between prenatal #cannabis use disorder and neonatal outcomes
Early-life #environmental exposure determinants of child #behavior in Europe: A longitudinal, population-based study
BackgroundEnvironmental exposures in early life influence the development of behavioral outcomes in children, but research has not considered multiple exposures. We therefore aimed to investigate the impact of a broad spectrum of pre- and postnatal environmental exposures on child behavior. Methods and findingsWe used data from the HELIX (Human Early Life Exposome) project, which was… Continue reading Early-life #environmental exposure determinants of child #behavior in Europe: A longitudinal, population-based study
Association of spontaneous #abortion with all cause and cause specific premature #mortality: prospective cohort study
To investigate the association of spontaneous abortion with the risk of all cause and cause specific premature mortality (death before the age of 70). Design Prospective cohort study. Setting The Nurses’ Health Study II (1993-2017), United States. Participants 101 681 ever gravid female nurses participating in the Nurses’ Health Study II. Main outcomes measures Lifetime occurrence… Continue reading Association of spontaneous #abortion with all cause and cause specific premature #mortality: prospective cohort study
OR10-1 – Efficacy of High-Intensity Intermittent #Training for Improving Cardio-Metabolic Health in Women With #Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is a common and complex endocrinopathy with significant metabolic and reproductive manifestations, carrying a major health and economic burden. Consistent improvements in clinical outcomes have been reported as a result of exercise training, but shortfalls with exercise prescription are evident. Research suggests that high-intensity intermittent training (HIIT) is feasible, well tolerated… Continue reading OR10-1 – Efficacy of High-Intensity Intermittent #Training for Improving Cardio-Metabolic Health in Women With #Polycystic Ovary Syndrome
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