Postpartum depression (PPD) is one of the most common medicalcomplications during and after pregnancy, negatively affecting both mother and child.OBJECTIVE To demonstrate the efficacy and safety of zuranolone, a neuroactive steroidΞ³-aminobutyric acid receptorβpositive allosteric modulator, in PPD. DESIGN, SETTING, AND PARTICIPANTS This phase 3, double-blind, randomized, outpatient,placebo-controlled clinical trial was conducted between January 2017 and …