Long-term Dietary #Flavonoid Intake and Subjective #Cognitive Decline in US Men and Women

To prospectively examine the associations between long-term dietary flavonoids and subjective cognitive decline (SCD). Methods: We followed 49,493 women from the Nurses’ Health Study (NHS) (1984-2006) and 27,842 men from the Health Professionals Follow-up Study (HPFS) (1986-2002). Poisson regression was used to evaluate the associations between dietary flavonoids (flavonols, flavones, flavanones, flavan-3-ols, anthocyanins, polymeric flavonoids,… Continue reading Long-term Dietary #Flavonoid Intake and Subjective #Cognitive Decline in US Men and Women

Distribution of dietary #protein intake in daily meals influences skeletal #muscle hypertrophy via the muscle clock

Distribution of dietary protein across meals influences muscle hypertrophy•BCAAs are involved in hypertrophic effects of protein feeding distribution•Hypertrophic effects of protein feeding distribution require the muscle clock•Breakfast protein intake is correlated with skeletal muscle functions in older women SummaryThe meal distribution of proteins throughout the day is usually skewed. However, its physiological implications and the… Continue reading Distribution of dietary #protein intake in daily meals influences skeletal #muscle hypertrophy via the muscle clock

Associations of #overweight and #obesity with drug-resistant #epilepsy

The group with epilepsy included in this study had a lower proportion of individuals with overweight and obesity than the general population (23.1% versus 42%) in 2015. However, the proportion of patients with obesity in the groups with DRE was significantly higher than that in the general population (17.9% versus 7.1%).•The J-shaped relationship between BMI… Continue reading Associations of #overweight and #obesity with drug-resistant #epilepsy

Influence of Free #Fatty Acid Concentrations and #Weight Loss on Adipose Tissue Direct Free Fatty Acid Storage Rates

The factors that determine the recycling of free fatty acids (FFA) back into different adipose tissue depots via the direct storage pathway are not completely understood. ObjectiveTo assess the interactions between adipocyte factors and plasma FFA concentrations that determine regional FFA storage rates. DesignWe measured direct adipose tissue FFA storage rates before and after weight… Continue reading Influence of Free #Fatty Acid Concentrations and #Weight Loss on Adipose Tissue Direct Free Fatty Acid Storage Rates

The Relationship Between Prognostic #Nutritional Index and All-Cause #Mortality in Critically Ill Patients: A Retrospective Study

The effectiveness and prognostic value of the prognostic nutritional index (PNI) in critically ill patients are unknown. Hence, this study aimed to analyze the relationship between the PNI and all-cause mortality in critically ill patients. Patients and Methods: Patient data were obtained from the Multiparameter Intelligent Monitoring in Intensive Care III database. The relationship between… Continue reading The Relationship Between Prognostic #Nutritional Index and All-Cause #Mortality in Critically Ill Patients: A Retrospective Study

#Gut-microbiota-targeted #diets modulate human immune status

Diet intervention with systems profiling reveals links in diet-microbiome-immune axis•High-fiber diet changes microbiome function and elicits personalized immune responses•Fermented-food diet increases microbiome diversity and decreases markers of inflammation SummaryDiet modulates the gut microbiome, which in turn can impact the immune system. Here, we determined how two microbiota-targeted dietary interventions, plant-based fiber and fermented foods, influence… Continue reading #Gut-microbiota-targeted #diets modulate human immune status

Consumption and Longitudinal Changes in #Cardiometabolic Risk Factors in the Framingham Offspring Cohort

Greater whole grain (WG) consumption is associated with reduced risk of cardiovascular disease (CVD); however, few prospective studies have examined WG or refined grain (RG) intake and intermediate cardiometabolic risk factors. ObjectivesWe examined the longitudinal association between WG and RG intake on changes in waist circumference (WC); fasting HDL cholesterol, triglyceride, and glucose concentrations; and… Continue reading Consumption and Longitudinal Changes in #Cardiometabolic Risk Factors in the Framingham Offspring Cohort

Association of ultra-processed #food intake with risk of #inflammatory bowel disease: prospective cohort study

To evaluate the relation between intake of ultra-processed food and risk of inflammatory bowel disease (IBD). Design Prospective cohort study. Setting 21 low, middle, and high income countries across seven geographical regions (Europe and North America, South America, Africa, Middle East, south Asia, South East Asia, and China). Participants 116 087 adults aged 35-70 years with… Continue reading Association of ultra-processed #food intake with risk of #inflammatory bowel disease: prospective cohort study

#Time-restricted feeding protects the blood #pressure circadian rhythm in #diabetic mice

The quantity and quality of food intake have been considered crucial for peoples' wellness. Only recently has it become appreciated that the timing of food intake is also critical. Nondipping blood pressure (BP) is prevalent in diabetic patients and is associated with increased cardiovascular events. However, the causes and mechanisms of nondipping BP in diabetes… Continue reading #Time-restricted feeding protects the blood #pressure circadian rhythm in #diabetic mice