The factors that determine the recycling of free fatty acids (FFA) back into different adipose tissue depots via the direct storage pathway are not completely understood. ObjectiveTo assess the interactions between adipocyte factors and plasma FFA concentrations that determine regional FFA storage rates. DesignWe measured direct adipose tissue FFA storage rates before and after weight… Continue reading Influence of Free #Fatty Acid Concentrations and #Weight Loss on Adipose Tissue Direct Free Fatty Acid Storage Rates
Category: Diet
The Relationship Between Prognostic #Nutritional Index and All-Cause #Mortality in Critically Ill Patients: A Retrospective Study
The effectiveness and prognostic value of the prognostic nutritional index (PNI) in critically ill patients are unknown. Hence, this study aimed to analyze the relationship between the PNI and all-cause mortality in critically ill patients. Patients and Methods: Patient data were obtained from the Multiparameter Intelligent Monitoring in Intensive Care III database. The relationship between… Continue reading The Relationship Between Prognostic #Nutritional Index and All-Cause #Mortality in Critically Ill Patients: A Retrospective Study
#Gut-microbiota-targeted #diets modulate human immune status
Diet intervention with systems profiling reveals links in diet-microbiome-immune axis•High-fiber diet changes microbiome function and elicits personalized immune responses•Fermented-food diet increases microbiome diversity and decreases markers of inflammation SummaryDiet modulates the gut microbiome, which in turn can impact the immune system. Here, we determined how two microbiota-targeted dietary interventions, plant-based fiber and fermented foods, influence… Continue reading #Gut-microbiota-targeted #diets modulate human immune status
Consumption and Longitudinal Changes in #Cardiometabolic Risk Factors in the Framingham Offspring Cohort
Greater whole grain (WG) consumption is associated with reduced risk of cardiovascular disease (CVD); however, few prospective studies have examined WG or refined grain (RG) intake and intermediate cardiometabolic risk factors. ObjectivesWe examined the longitudinal association between WG and RG intake on changes in waist circumference (WC); fasting HDL cholesterol, triglyceride, and glucose concentrations; and… Continue reading Consumption and Longitudinal Changes in #Cardiometabolic Risk Factors in the Framingham Offspring Cohort
Association of ultra-processed #food intake with risk of #inflammatory bowel disease: prospective cohort study
To evaluate the relation between intake of ultra-processed food and risk of inflammatory bowel disease (IBD). Design Prospective cohort study. Setting 21 low, middle, and high income countries across seven geographical regions (Europe and North America, South America, Africa, Middle East, south Asia, South East Asia, and China). Participants 116 087 adults aged 35-70 years with… Continue reading Association of ultra-processed #food intake with risk of #inflammatory bowel disease: prospective cohort study
#Time-restricted feeding protects the blood #pressure circadian rhythm in #diabetic mice
The quantity and quality of food intake have been considered crucial for peoples' wellness. Only recently has it become appreciated that the timing of food intake is also critical. Nondipping blood pressure (BP) is prevalent in diabetic patients and is associated with increased cardiovascular events. However, the causes and mechanisms of nondipping BP in diabetes… Continue reading #Time-restricted feeding protects the blood #pressure circadian rhythm in #diabetic mice
Self-tunable engineered yeast #probiotics for the treatment of #inflammatory bowel disease
Inflammatory bowel disease (IBD) is a complex chronic inflammatory disorder of the gastrointestinal tract. Extracellular adenosine triphosphate (eATP) produced by the commensal microbiota and host cells activates purinergic signaling, promoting intestinal inflammation and pathology. Based on the role of eATP in intestinal inflammation, we developed yeast-based engineered probiotics that express a human P2Y2 purinergic receptor… Continue reading Self-tunable engineered yeast #probiotics for the treatment of #inflammatory bowel disease
A Systematic Review of Dietary #Supplements and Alternative Therapies for #Weight Loss
Dietary supplements and alternative therapies are commercialized as a panacea for obesity/weight gain as a result of the minimal regulatory requirements in demonstrating efficacy. These products may indirectly undermine the value of guideline-driven obesity treatments. Included in this study is a systematic review of the literature of purported dietary supplements and alternative therapies for weight… Continue reading A Systematic Review of Dietary #Supplements and Alternative Therapies for #Weight Loss
Common #dandelion (Taraxacum officinale) efficiently blocks the interaction between ACE2 cell surface receptor and #SARS-CoV-2 spike protein D614, mutants D614G, N501Y, K417N and E484K in vitro
bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive. On 11th March 2020, coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, was declared as a global pandemic by the World Health Organization (WHO). To date, there… Continue reading Common #dandelion (Taraxacum officinale) efficiently blocks the interaction between ACE2 cell surface receptor and #SARS-CoV-2 spike protein D614, mutants D614G, N501Y, K417N and E484K in vitro