Associations of #overweight and #obesity with drug-resistant #epilepsy

The group with epilepsy included in this study had a lower proportion of individuals with overweight and obesity than the general population (23.1% versus 42%) in 2015. However, the proportion of patients with obesity in the groups with DRE was significantly higher than that in the general population (17.9% versus 7.1%).β€’The J-shaped relationship between BMI …

Continue reading Associations of #overweight and #obesity with drug-resistant #epilepsy

Effects of double-dose #statin therapy for the prevention of post- #stroke #epilepsy: A prospective clinical study

To determine treatment effects on the incidence of post-stroke epilepsy (PSE) using different doses of statin, a prospective hospital-based cohort study was designed to explore whether a double-dose statin treatment can better prevent the occurrence of PSE. Methods :A total of 1152 patients with newly diagnosed ischemic stroke admitted to our hospital from March to …

Continue reading Effects of double-dose #statin therapy for the prevention of post- #stroke #epilepsy: A prospective clinical study

Incidence rates of severe #cutaneous adverse reactions due to anti #seizure medication: A nationwide study using health claims data in Korea

Antiseizure medications (ASMs) can rarely result in severe, sometimes fatal, cutaneous adverse reactions. To date, few studies have reported on the incidence rates (IRs) of severe cutaneous adverse reactions (SCARs) due to ASM use. This study aimed to determine the IRs of SCAR resulting from the use of seven commonly prescribed ASMs, carbamazepine (CBZ), phenytoin …

Continue reading Incidence rates of severe #cutaneous adverse reactions due to anti #seizure medication: A nationwide study using health claims data in Korea

#Cognitive decline in older adults with #epilepsy: The Cardiovascular Health Study

Cognitive decline is a major concern for older adults with epilepsy. Whether and how much faster older adults with epilepsy experience cognitive decline beyond expected age‐related cognitive change remain unclear. We sought to estimate and compare rates of cognitive decline in older adults with and without epilepsy.. ..The rate of decline in 3MS was significantly …

Continue reading #Cognitive decline in older adults with #epilepsy: The Cardiovascular Health Study

Nine-year prospective efficacy and safety of brain-responsive #neurostimulation for focal #epilepsy

Prospectively evaluate safety and efficacy of brain-responsive neurostimulation in adults with medically intractable focal onset seizures (FOS) over 9 years.. Adults treated with brain-responsive neurostimulation within 2 year feasibility or randomized controlled trials enrolled into a long-term prospective open label trial (LTT) to assess safety, efficacy, and quality of life (QOL) over an additional 7 …

Continue reading Nine-year prospective efficacy and safety of brain-responsive #neurostimulation for focal #epilepsy