Although there is a strong association between obesity and obstructive sleep apnoea (OSA), the effects of OSA and CPAP therapy on weight loss are less well known. The aim of this study in adults with class 3 obesity attending a multidisciplinary weight management program was to assess the relationship between OSA and CPAP usage, and… Continue reading Obstructive sleep apnoea and 12-month weight loss in adults with class 3 obesity attending a multidisciplinary weight management program
Category: Diet
Vitamin D and Marine n-3 Fatty Acid Supplementation and Prevention of Autoimmune Disease in the VITAL Randomized Controlled Trial
In observational studies, vitamin D has been inconsistently associated with reduced risk of several autoimmune diseases, and a large randomized, controlled trial has been lacking. Dietary marine-derived long-chain omega-3 (n−3) fatty acids decrease systemic inflammation and ameliorate symptoms in some autoimmune diseases, but no trials have tested whether supplementation lowers risk of developing autoimmune disease.… Continue reading Vitamin D and Marine n-3 Fatty Acid Supplementation and Prevention of Autoimmune Disease in the VITAL Randomized Controlled Trial
Consumption of coffee and tea and risk of developing stroke, dementia, and poststroke dementia: A cohort study in the UK Biobank
Previous studies have revealed the involvement of coffee and tea in the development of stroke and dementia. However, little is known about the association between the combination of coffee and tea and the risk of stroke, dementia, and poststroke dementia. Therefore, we aimed to investigate the associations of coffee and tea separately and in combination… Continue reading Consumption of coffee and tea and risk of developing stroke, dementia, and poststroke dementia: A cohort study in the UK Biobank
2021 #Dietary Guidance to Improve #Cardiovascular Health: A Scientific Statement From the American Heart Association
Poor diet quality is strongly associated with elevated risk of cardiovascular disease morbidity and mortality. This scientific statement emphasizes the importance of dietary patterns beyond individual foods or nutrients, underscores the critical role of nutrition early in life, presents elements of heart-healthy dietary patterns, and highlights structural challenges that impede adherence to heart-healthy dietary patterns.… Continue reading 2021 #Dietary Guidance to Improve #Cardiovascular Health: A Scientific Statement From the American Heart Association
Estimating dose-response relationships for vitamin #D with #coronary heart disease, #stroke, and all-cause mortality: observational and Mendelian randomisation analyses
SummaryBackgroundRandomised trials of vitamin D supplementation for cardiovascular disease and all-cause mortality have generally reported null findings. However, generalisability of results to individuals with low vitamin D status is unclear. We aimed to characterise dose-response relationships between 25-hydroxyvitamin D (25[OH]D) concentrations and risk of coronary heart disease, stroke, and all-cause mortality in observational and Mendelian… Continue reading Estimating dose-response relationships for vitamin #D with #coronary heart disease, #stroke, and all-cause mortality: observational and Mendelian randomisation analyses
Relationship Between #Ultraprocessed Food Intake and #Cardiovascular Health Among U.S. Adolescents: Results From the National Health and Nutrition Examination Survey 2007–2018
Studies of the association between ultraprocessed foods (UPF) and cardiovascular disease risk factors have been mainly focused on the adult population. This study examined the association between usual percentage of calories (%kcal) from UPF and the American Heart Association's seven cardiovascular health (CVH) metrics among U.S. adolescents aged 12–19 years. MethodsWe used data from the… Continue reading Relationship Between #Ultraprocessed Food Intake and #Cardiovascular Health Among U.S. Adolescents: Results From the National Health and Nutrition Examination Survey 2007–2018
Role of Adipocyte Na,K-ATPase Oxidant Amplification Loop in #Cognitive Decline and #Neurodegeneration
•Adipocytes induce phenotypical changes in neurodegeneration through adipocyte NKAL.•Adipocyte specific NaKtide inhibited NKAL and improved systemic homeostasis.•NaKtide improved adipocyte phenotype and improved markers of neurodegeneration.•NaKtide improved genomic profile of hippocampus and adipose tissue in WD fed mice. SummaryRecent studies suggest that a western diet may contribute to clinical neurodegeneration and dementia. Adipocyte-specific expression of the… Continue reading Role of Adipocyte Na,K-ATPase Oxidant Amplification Loop in #Cognitive Decline and #Neurodegeneration
Impact of Sustained #Weight Loss on #Cardiometabolic Outcomes
Highlights•Sustained weight loss significantly lowers incidence of cardiometabolic outcomes.•Sustained weight loss significantly delays onset of cardiometabolic outcomes.•Greater weight loss significantly delays onset of cardiometabolic outcomes. Obesity increases the risk of developing type 2 diabetes, hypertension, and hyperlipidemia. We sought to determine the impact of obesity maintenance, weight regain, weight loss maintenance, and magnitudes of weight… Continue reading Impact of Sustained #Weight Loss on #Cardiometabolic Outcomes
#Nut consumption in association with overall mortality and recurrence/disease-specific mortality among long-term breast #cancer survivors
High nut consumption is associated with reduced total and certain cause-specific mortality in general populations. However, its association with cancer outcomes among long-term breast cancer survivors remains unknown. We examined the associations of nut consumption (including peanuts and tree nuts), assessed at 5-year postdiagnosis, with overall survival (OS) and disease-free survival (DFS) among 3449 long-term… Continue reading #Nut consumption in association with overall mortality and recurrence/disease-specific mortality among long-term breast #cancer survivors
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