Association between vitamin D status and risk of covid-19 in-hospital mortality: A systematic review and meta-analysis of observational studies

Some earlier studies reported higher risk of COVID-19 mortality in patients with vitamin D deficiency, while some others failed to find such as association. Due to inconsistences between earlier meta-analyses and needs for an updated study, we conducted current systematic review and meta-analysis on the association between vitamin D status and risk of COVID-19 in-hospital… Continue reading Association between vitamin D status and risk of covid-19 in-hospital mortality: A systematic review and meta-analysis of observational studies

Non-linear Mendelian randomization analyses support a role for vitamin D deficiency in cardiovascular disease risk

Low vitamin D status is associated with a higher risk for cardiovascular diseases (CVDs). Although most existing linear Mendelian randomization (MR) studies reported a null effect of vitamin D on CVD risk, a non-linear effect cannot be excluded. Our aim was to apply the non-linear MR design to investigate the association of serum 25-hydroxyvitamin D… Continue reading Non-linear Mendelian randomization analyses support a role for vitamin D deficiency in cardiovascular disease risk

Therapies to Prevent Progression of COVID-19, Including Hydroxychloroquine, Azithromycin, Zinc, and Vitamin D3 With or Without Intravenous Vitamin C: An International, Multicenter, Randomized Trial

Therapies to Prevent Progression of COVID-19, Including Hydroxychloroquine, Azithromycin, Zinc, and Vitamin D3 With or Without Intravenous Vitamin C: An International, Multicenter, Randomized TrialKarin Ried, Taufiq BinJemain, Avni Sali Published: November 25, 2021 (see history) DOI: 10.7759/cureus.19902 Cite this article as: Ried K, BinJemain T, Sali A (November 25, 2021) Therapies to Prevent Progression of… Continue reading Therapies to Prevent Progression of COVID-19, Including Hydroxychloroquine, Azithromycin, Zinc, and Vitamin D3 With or Without Intravenous Vitamin C: An International, Multicenter, Randomized Trial

Alcohol consumption and risk of ventricular arrhythmias and sudden cardiac death: An observational study of 408,712 individuals

Although previous studies have demonstrated a U-shaped relationship between alcohol and sudden cardiac death (SCD), there is a paucity of evidence on the role of alcohol specifically on incident ventricular arrhythmias (VAs). ObjectiveThe purpose of this study was to characterize associations of total and beverage-specific alcohol consumption with incident VA and SCD using data from… Continue reading Alcohol consumption and risk of ventricular arrhythmias and sudden cardiac death: An observational study of 408,712 individuals

Intermittent fasting: is there a role in the treatment of diabetes? A review of the literature and guide for primary care physicians

Type 2 Diabetes is a metabolic disorder characterized by hyperglycemia that causes numerous complications with significant long-term morbidity and mortality. The disorder is primarily due to insulin resistance particularly in liver, skeletal muscle, and adipose tissue. In this review, we detail the hormonal mechanisms leading to the development of diabetes and discuss whether intermittent fasting… Continue reading Intermittent fasting: is there a role in the treatment of diabetes? A review of the literature and guide for primary care physicians

Role of nutritional supplements in selected dermatological disorders: A review

While a plethora of literature continues to be published on the role of nutritional agents both in lay press and indexed journals, the data is not on a firm footing and leaves the dermatologist in a quandry and the patient confused. The various agents include vitamins, minerals, amino acids, antioxidants, diets & gluten. A proper… Continue reading Role of nutritional supplements in selected dermatological disorders: A review

Association of Metabolic Health and Central Obesity With the Risk of Thyroid Cancer: Data from the Korean Genome and Epidemiology Study

Background:It is unknown whether the risk of thyroid cancer differs among metabolically healthy/unhealthy, normal-weight, or obese women. We aimed to assess the association of metabolic health and obesity with thyroid cancer risk. Methods:The Korean Genome and Epidemiology Study is a population-based prospective cohort study. Data were obtained from 173,343 participants (age {greater than or equal… Continue reading Association of Metabolic Health and Central Obesity With the Risk of Thyroid Cancer: Data from the Korean Genome and Epidemiology Study

Industry Funding and Cholesterol Research: A Systematic Review

The effect of diet on blood cholesterol concentrations has become controversial. We assessed whether industry-funded studies were more likely than non–industry-funded studies to report conclusions that were not supported by their objective findings. PubMed and Cochrane Central Register of Controlled Trials searches through March 8, 2019, yielded 211 relevant articles. The percentage of industry-funded studies… Continue reading Industry Funding and Cholesterol Research: A Systematic Review

Food Insecurity is Associated with Mortality Among U.S. Adults with Nonalcoholic Fatty Liver Disease and Advanced Fibrosis

Food insecurity is a growing public health challenge in the U.S. and has been linked to nonalcoholic fatty liver disease (NAFLD) and advanced fibrosis. However, little is known of how food insecurity impacts mortality risk and healthcare utilization (HCU) in chronic liver disease. MethodsUsing a population-based cohort study of U.S. adults (≥20 years) in the… Continue reading Food Insecurity is Associated with Mortality Among U.S. Adults with Nonalcoholic Fatty Liver Disease and Advanced Fibrosis