We identified seasonal human coronaviruses, influenza viruses and rhinoviruses in exhaled breath and coughs of children and adults with acute respiratory illness. Surgical face masks significantly reduced detection of influenza virus RNA in respiratory droplets and coronavirus RNA in aerosols, with a trend toward reduced detection of coronavirus RNA in respiratory droplets. Our results indicate… Continue reading Respiratory virus shedding in exhaled breath and efficacy of face #masks
Evolving Epidemiology and Impact of Non-pharmaceutical Interventions on the Outbreak of #Coronavirus Disease 2019 in Wuhan, China
..The median age of the cases was 57 years and 50.3% were women. The attack rate peaked in the third period and substantially declined afterwards across geographic regions, sex and age groups, except for children (age <20) whose attack rate continued to increase. Healthcare workers and elderly people had higher attack rates and severity risk… Continue reading Evolving Epidemiology and Impact of Non-pharmaceutical Interventions on the Outbreak of #Coronavirus Disease 2019 in Wuhan, China
A high-#salt diet compromises antibacterial neutrophil responses through hormonal perturbation
The Western diet is rich in salt, which poses various health risks. A high-salt diet (HSD) can stimulate immunity through the nuclear factor of activated T cells 5 (Nfat5)–signaling pathway, especially in the skin, where sodium is stored. The kidney medulla also accumulates sodium to build an osmotic gradient for water conservation. Here, we studied… Continue reading A high-#salt diet compromises antibacterial neutrophil responses through hormonal perturbation
Seasonality of Respiratory Viral Infections
The seasonal cycle of respiratory viral diseases has been widely recognized for thousands of years, as annual epidemics of the common cold and influenza disease hit the human population like clockwork in the winter season in temperate regions. Moreover, epidemics caused by viruses such as severe acute respiratory syndrome coronavirus (SARS-CoV) and the newly emerging… Continue reading Seasonality of Respiratory Viral Infections
Chronic #obstructive pulmonary disease and lung cancer incidence in never smokers: a cohort study
There has been limited evidence for the association between chronic obstructive pulmonary disease (COPD) and the incidence of lung cancer among never smokers. We aimed to estimate the risk of lung cancer incidence in never smokers with COPD, and to compare it with the risk associated with smoking. This cohort study involved 338 548 subjects, 40… Continue reading Chronic #obstructive pulmonary disease and lung cancer incidence in never smokers: a cohort study
Comparison of dietary macronutrient patterns of 14 popular named dietary programmes for #weight and cardiovascular risk factor reduction in adults: systematic review and network meta-analysis of randomised trials
..Compared with usual diet, low carbohydrate and low fat diets had a similar effect at six months on weight loss (4.63 v 4.37 kg, both moderate certainty) and reduction in systolic blood pressure (5.14 mm Hg, moderate certainty v 5.05 mm Hg, low certainty) and diastolic blood pressure (3.21 v 2.85 mm Hg, both low… Continue reading Comparison of dietary macronutrient patterns of 14 popular named dietary programmes for #weight and cardiovascular risk factor reduction in adults: systematic review and network meta-analysis of randomised trials
Timing of #Endoscopy for Acute Upper Gastrointestinal #Bleeding
To evaluate whether urgent endoscopy improves outcomes in patients predicted to be at high risk for further bleeding or death, we randomly assigned patients with overt signs of acute upper gastrointestinal bleeding and a Glasgow–Blatchford score of 12 or higher (scores range from 0 to 23, with higher scores indicating a higher risk of further… Continue reading Timing of #Endoscopy for Acute Upper Gastrointestinal #Bleeding
Estimates of the severity of #coronavirus disease 2019: a model-based analysis
Using data on 24 deaths that occurred in mainland China and 165 recoveries outside of China, we estimated the mean duration from onset of symptoms to death to be 17·8 days (95% credible interval [CrI] 16·9–19·2) and to hospital discharge to be 24·7 days (22·9–28·1). In all laboratory confirmed and clinically diagnosed cases from mainland… Continue reading Estimates of the severity of #coronavirus disease 2019: a model-based analysis
Plant‐based and animal‐based low‐carbohydrate #diets and risk of #hepatocellular carcinoma among US men and women
Little is known about the role of low‐carbohydrate diets (LCDs) in the development of hepatocellular carcinoma (HCC).. ..During 3,664,769 person years of follow‐up, there were 156 incident HCC cases. Although there were no associations between overall or animal‐based LCD score and risk of HCC, plant‐based LCD score was inversely associated with HCC risk (HR: 0.83;… Continue reading Plant‐based and animal‐based low‐carbohydrate #diets and risk of #hepatocellular carcinoma among US men and women
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