Introduction: When a patient's presentation raises suspicions for conditions other than diabetic kidney disease (DKD), such as sudden onset proteinuria <5 years after the onset of type 2 diabetes, proteinuria without retinopathy or neuropathy, acute kidney injury, active urinary sediment, or hematuria, clinically indicated kidney biopsies are typically carried out. Consequently, a high incidence of… Continue reading Clinical Predictors and Histopathological Spectrum of Nondiabetic Kidney Disease in Type 2 Diabetes
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Are Foods with #Protein Claims Healthy? A Study of the Spanish Market
Background: Foods with protein claims (PCs) targeted at the general population are increasingly sought after by consumers because they think they are healthy. However, they may contain other nutrients that pose a health risk. Objectives: Therefore, the aim of this work was to carry out a comprehensive evaluation of foods with PC and compare them… Continue reading Are Foods with #Protein Claims Healthy? A Study of the Spanish Market
#Stress -resilience impacts psychological wellbeing as evidenced by brain–gut #microbiome interactions
The brain–gut microbiome (BGM) system plays an influential role on mental health. We characterized BGM patterns related to resilience using fecal samples and multimodal magnetic resonance imaging. Data integration analysis using latent components showed that the high-resilience phenotype was associated with lower depression and anxiety symptoms, higher frequency of bacterial transcriptomes (related to environmental adaptation,… Continue reading #Stress -resilience impacts psychological wellbeing as evidenced by brain–gut #microbiome interactions
Why Do We Get Fever?
Fever, or pyrexia, refers to an increase in body temperature beyond its normal range. While our temperature may vary slightly during the course of the day (by not more than 1.0°C – 1.5 °C, usually higher in the evening than in the morning) and due to other factors such as exercise, menstrual cycle phase, hot… Continue reading Why Do We Get Fever?
(P06-010-23) Determination of the #Prebiotic Content of #Foods in the 2015-2016 Food and #Nutrient Database for Dietary Studies (FNDDS)
Consuming prebiotics positively impacts health. According to the International Scientific Association for Probiotics and Prebiotics (ISAPP), the recognized prebiotics include inulin-like fructans (inulin, FOS, oligofructose) and GOS, and 5 g/d consumed is the minimum needed to confer a health benefit. Currently, there is no database that provides the prebiotic content of food based on these… Continue reading (P06-010-23) Determination of the #Prebiotic Content of #Foods in the 2015-2016 Food and #Nutrient Database for Dietary Studies (FNDDS)
Ultrasonography or Radiography for Suspected Pediatric Distal Forearm Fractures
Data on whether ultrasonography for the initial diagnostic imaging of forearm fractures in children and adolescents is noninferior to radiography for subsequent physical function of the arm are limited. In this open-label, multicenter, noninferiority, randomized trial in Australia, we recruited participants 5 to 15 years of age who presented to the emergency department with an… Continue reading Ultrasonography or Radiography for Suspected Pediatric Distal Forearm Fractures
Hericerin derivatives activates a pan-neurotrophic pathway in central hippocampal neurons converging to ERK1/2 signaling enhancing spatial memory
The traditional medicinal mushroom Hericium erinaceus is known for enhancing peripheral nerve regeneration through targeting nerve growth factor (NGF) neurotrophic activity. Here, we purified and identified biologically new active compounds from H. erinaceus, based on their ability to promote neurite outgrowth in hippocampal neurons. N-de phenylethyl isohericerin (NDPIH), an isoindoline compound from this mushroom, together… Continue reading Hericerin derivatives activates a pan-neurotrophic pathway in central hippocampal neurons converging to ERK1/2 signaling enhancing spatial memory
Mask mandate and use efficacy for COVID-19 containment in US States
Background: COVID-19 pandemic mitigation requires evidence-based strategies. Because COVID-19 can spread via respired droplets, most US states mandated mask use in public settings. Randomized control trials have not clearly demonstrated mask efficacy against respiratory viruses, and observational studies conflict on whether mask use predicts lower infection rates. We hypothesized that statewide mask mandates and mask… Continue reading Mask mandate and use efficacy for COVID-19 containment in US States
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