Changes in Body #Mass Index Are Related to Faster #Cognitive Decline Among African American Older Adults

The purpose of this study was to: (1) examine relationships between body mass index (BMI) stability and cognitive decline in older African Americans; and (2) investigate differences in the relationships between women and men.. ..Participants (n = 671; mean age = 73.5 years; standard deviation = 6.2 years) were included in the present analysis if they were… Continue reading Changes in Body #Mass Index Are Related to Faster #Cognitive Decline Among African American Older Adults

#IgA dominates the early neutralizing antibody response to #SARS-CoV-2

Abstract Humoral immune responses are typically characterized by primary IgM antibody responses followed by secondary antibody responses associated with immune memory and comprised of of IgG, IgA and IgE. Here we measured acute humoral responses to SARS-CoV-2, including the frequency of antibody-secreting cells and the presence of SARS-CoV-2-specific neutralizing antibodies in the serum, saliva and… Continue reading #IgA dominates the early neutralizing antibody response to #SARS-CoV-2

#Blood type #diets lack supporting evidence: a systematic review

Background: Diets that are based on the ABO blood group system have been promoted over the past decade and claim to improve health and decrease risk of disease. To our knowledge, the evidence to support the effectiveness of blood type diets has not previously been assessed in the scientific literature. Objective: In this current systematic… Continue reading #Blood type #diets lack supporting evidence: a systematic review

Association between circulating #vascular-related microRNAs and an increase in blood #pressure: a 5-year longitudinal population-based study

MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression and play essential roles in the pathogenesis of cardiovascular disease. Previous cross-sectional studies showed that the levels of several circulating miRNA are associated with hypertension, but there are no prospective longitudinal studies using a general population. The aim of this study is to evaluate the… Continue reading Association between circulating #vascular-related microRNAs and an increase in blood #pressure: a 5-year longitudinal population-based study

Human #Health and Ocean #Pollution

..Human Health Findings: Methylmercury and PCBs are the ocean pollutants whose human health effects are best understood. Exposures of infants in utero to these pollutants through maternal consumption of contaminated seafood can damage developing brains, reduce IQ and increase children’s risks for autism, ADHD and learning disorders. Adult exposures to methylmercury increase risks for cardiovascular… Continue reading Human #Health and Ocean #Pollution

Effects of #probiotics on gut #microbiota: mechanisms of intestinal immunomodulation and neuromodulation

Recent explorations of the human gut microbiota suggest that perturbations of microbial communities may increase predisposition to different disease phenotypes. Dietary nutrients may be converted into metabolites by intestinal microbes that serve as biologically active molecules affecting regulatory functions in the host. Probiotics may restore the composition of the gut microbiome and introduce beneficial functions… Continue reading Effects of #probiotics on gut #microbiota: mechanisms of intestinal immunomodulation and neuromodulation

UK probes whether #COVID-19 vaccine caused #allergic reactions

LONDON (AP) — Britain’s medical regulator warned Wednesday that people with a history of serious allergic reactions shouldn’t get the COVID-19 vaccine from Pfizer and BioNTech, and investigators looked into whether two reactions on the first day of the U.K.’s vaccination program were linked to the shot. The advice was issued on a “precautionary basis,”… Continue reading UK probes whether #COVID-19 vaccine caused #allergic reactions

#EPA and #DHA differentially modulate monocyte #inflammatory response in subjects with chronic inflammation in part via plasma specialized pro-resolving lipid mediators: A randomized, double-blind, crossover study

The independent effects of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on chronic inflammation through their downstream lipid mediators, including the specialized pro-resolving lipid mediators (SPM), remain unstudied. Therefore, we compared the effects of EPA and DHA supplementation on monocyte inflammatory response and plasma polyunsaturated fatty acids (PUFA) SPM lipidome.. After a 4-week lead-in phase… Continue reading #EPA and #DHA differentially modulate monocyte #inflammatory response in subjects with chronic inflammation in part via plasma specialized pro-resolving lipid mediators: A randomized, double-blind, crossover study

#Cooking as a Health Behavior: Examining the Role of Cooking Classes in a #Weight Loss Intervention

Americans are cooking fewer meals at home and eating more convenience foods prepared elsewhere. Cooking at home is associated with higher quality diets, while a reduction in cooking may be associated with increases in obesity and risk factors for chronic disease. The aims of this study were to examine cooking as an intervention for weight… Continue reading #Cooking as a Health Behavior: Examining the Role of Cooking Classes in a #Weight Loss Intervention