Background: Diabetic retinopathy (DR) is a predominant microvascular complication in patients with type 2 diabetes mellitus (T2DM) and constitutes one of the leading causes of vision loss and blindness among this population. Serum uric acid (SUA) acts as a critical biomarker for microangiopathy; however, its relationship with DR remains incompletely elucidated. To adjust for inter-individual… Continue reading Correlation between serum uric acid-to-creatinine ratio and diabetic retinopathy in type 2 diabetes mellitus patients
Category: Ophthalmology
Retinal and coronary imaging in type 1 diabetes: links between retinopathy and subclinical cardiovascular disease
Cardiovascular disease (CVD) remains the leading cause of premature morbidity and mortality in individuals with type 1 diabetes mellitus (T1DM), despite advances in glycemic management and cardiovascular prevention. Conventional cardiovascular risk assessment may underestimate risk in T1DM, particularly among younger asymptomatic individuals, highlighting the need for markers of early vascular injury. Diabetic retinopathy (DR), a… Continue reading Retinal and coronary imaging in type 1 diabetes: links between retinopathy and subclinical cardiovascular disease
The Impact of Glucagon-Like Peptide-1 Receptor Agonists on Risk of Retinal Vascular Occlusions
Purpose: To investigate whether glucagon-like peptide-1 receptor agonists are protective against retinal vascular occlusions. Methods: Using a large aggregated, de-identified electronic health records data platform in the United States, patients with type 2 diabetes ages ≥18 years prescribed glucagon-like peptide-1 receptor agonists or non-glucagon-like peptide-1 receptor agonists (controls) and having ophthalmology follow-up of at least… Continue reading The Impact of Glucagon-Like Peptide-1 Receptor Agonists on Risk of Retinal Vascular Occlusions
Airbag-Related Ocular and Facial Trauma in Unrestrained Pediatric Front-Seat Passengers: A Report of Two Cases
Airbags are considered a crucial safety feature in vehicles, offering significant protection by cushioning the occupants during collisions. During a collision, sudden deceleration or impact within a specified angle relative to the vehicle's longitudinal axis triggers crash sensors throughout the vehicle. These sensors send an electrical signal to the airbag cartridge, which rapidly inflates the… Continue reading Airbag-Related Ocular and Facial Trauma in Unrestrained Pediatric Front-Seat Passengers: A Report of Two Cases
Development and validation of a deep learning model to predict visual and anatomical prognosis of anti-VEGF therapy for neovascular age-related macular degeneration (KongMing Study): a prospective, nationwide, multicentre study
Background: The financial burden and the uncertain response of the anti-vascular endothelial growth factor (anti-VEGF) treatment often cause hesitation among patients with neovascular age-related #macular degeneration (nAMD), highlighting the need for a reliable method to predict treatment outcomes. We aimed to develop and validate a deep learning model that can predict the visual and anatomical… Continue reading Development and validation of a deep learning model to predict visual and anatomical prognosis of anti-VEGF therapy for neovascular age-related macular degeneration (KongMing Study): a prospective, nationwide, multicentre study
#Subretinal Photovoltaic Implant to Restore #Vision in Geographic Atrophy Due to AMD
Geographic atrophy due to age-related macular degeneration (AMD) is the leading cause of irreversible blindness and affects more than 5 million persons worldwide. No therapies to restore vision in such persons currently exist. The photovoltaic retina implant microarray (PRIMA) system combines a subretinal photovoltaic implant and glasses that project near-infrared light to the implant in… Continue reading #Subretinal Photovoltaic Implant to Restore #Vision in Geographic Atrophy Due to AMD
#Retinal vascular dysfunction in the Mthfr677C>T mouse model of #cerebrovascular disease
INTRODUCTIONInvestigations of retinal biomarkers for #Alzheimer's disease (AD) and AD and related dementias (ADRD), has increased significantly. We examine retinal vascular health in a mouse containing the ADRD risk variant Mthfr677C>T to determine if changes in retina mirror similar changes in cerebrovasculature.METHODSMorphology and function of retinal vasculature and neurons were assessed using in vivo imaging,… Continue reading #Retinal vascular dysfunction in the Mthfr677C>T mouse model of #cerebrovascular disease
Digital #Eye #Strain Monitoring for One-Hour #Smartphone Engagement Through Eye Activity Measurement System
Smartphones have revolutionized our daily lives, becoming portable pocket computers with easy internet access. India, the second-highest smartphone and internet user, experienced a significant rise in smartphone usage between 2013 and 2024. Prolonged smartphone use, exceeding 20 min at a time, can lead to physical and mental health issues, including psychophysiological disorders. Digital devices and… Continue reading Digital #Eye #Strain Monitoring for One-Hour #Smartphone Engagement Through Eye Activity Measurement System
Decoding #memory function through naturalistic gaze patterns
#Eye movements are closely linked to encoding and retrieval processes, with changes in viewing behavior reflecting age- and pathology-related memory decline. In the current study, we leveraged this relationship to explore possible gaze-based indicators of memory function. Across two task-free viewing experiments, we investigated changes in naturalistic viewing behavior across five participant groups spanning a… Continue reading Decoding #memory function through naturalistic gaze patterns
