Effect of Vitamin #D and ω-3 #Fatty Acid Supplementation on Risk of Age-Related #Macular Degeneration An Ancillary Study of the VITAL Randomized Clinical Trial

Observational studies suggest that higher intake or blood levels of vitamin D and marine ω-3 fatty acids may be associated with lower risks of age-related macular degeneration (AMD). However, evidence from randomized trials is limited.. ..In total, 25 871 participants with a mean (SD) age of 67.1 (7.0) years were included in the trial. Of them, 50.6% were women, 71.3% were self-declared non-Hispanic White participants, and … Continue reading Effect of Vitamin #D and ω-3 #Fatty Acid Supplementation on Risk of Age-Related #Macular Degeneration An Ancillary Study of the VITAL Randomized Clinical Trial

Neurofilament light chain in the vitreous humor of the #eye

Neurofilament light chain (NfL) is a promising biomarker of neurodegeneration in the cerebrospinal fluid and blood. This study investigated the presence of NfL in the vitreous humor and its associations with amyloid beta, tau, inflammatory cytokines and vascular proteins, apolipoprotein E (APOE) genotypes, Mini-Mental State Examination (MMSE) scores, systemic disease, and ophthalmic diseases.. ..NfL was detected in all 77 vitreous samples. NfL was not found … Continue reading Neurofilament light chain in the vitreous humor of the #eye