The long‐term incidence of acute myocardial infarction (AMI) in patients with acute ischemic stroke (AIS) has not been well defined in large cohort studies of various race‐ethnic groups. A prospective cohort of patients with AIS who were registered in a multicenter nationwide stroke registry (CRCS‐K [Clinical Research Collaboration for Stroke in Korea] registry) was followed… Continue reading Five‐Year Risk of Acute #Myocardial Infarction After Acute Ischemic #Stroke in Korea
Low vitamin #D status is associated with #coronavirus disease 2019 outcomes: A systematic review and meta-analysis
Observational studies suggest that the risk and clinical prognosis of coronavirus disease 2019 (COVID-19) are related to low vitamin D status; however, the data are inconsistent.. ..A total of 10 articles with 361, 934 participants were selected for meta-analysis. Overall, the pooled OR in the fixed-effect model showed that vitamin D deficiency or insufficiency was… Continue reading Low vitamin #D status is associated with #coronavirus disease 2019 outcomes: A systematic review and meta-analysis
#Plastics, #EDCs & Health: Authoritative Guide
The Endocrine Society and IPEN (International Pollutants Elimination Network) are proud to present this authoritative and comprehensive report to addresses how plastics can harm human health. An expert overview of twenty years of research shows that plastics pose a threat to public health because they contain a host of hazardous, endocrine-disrupting chemicals (EDCs) that leach… Continue reading #Plastics, #EDCs & Health: Authoritative Guide
mRNA #Covid-19 #vaccines
The Advisory Committee on Immunization Practices (ACIP) has issued interim recommendations for the use of Pfizer-BioNTech and Moderna COVID-19 vaccines for the prevention of coronavirus disease 2019 (COVID-19) in the United States. Both vaccines are lipid nanoparticle-formulated, nucleoside-modified mRNA vaccines encoding the prefusion spike glycoprotein of SARS-CoV-2, the virus that causes COVID-19. These interim CDC… Continue reading mRNA #Covid-19 #vaccines
Distinct developmental pathways from blood #monocytes generate human #lung macrophage diversity
The study of human macrophages and their ontogeny is an important unresolved issue. Here, we use a humanized mouse model expressing human cytokines to dissect the development of lung macrophages from human hematopoiesis in vivo. Human CD34+ hematopoietic stem and progenitor cells (HSPCs) generated three macrophage populations, occupying separate anatomical niches in the lung. Intravascular… Continue reading Distinct developmental pathways from blood #monocytes generate human #lung macrophage diversity
U.S. #Diet Guidelines Sidestep Scientific Advice to Cut #Sugar and #Alcohol
..Evidence suggests that added sugars, particularly those in sweetened beverages, may contribute to obesity and weight gain, which are linked to higher rates of chronic health conditions like heart disease and Type 2 diabetes, the scientific panel noted. More than two-thirds of American adults are overweight or obese; obesity, diabetes and other related conditions also… Continue reading U.S. #Diet Guidelines Sidestep Scientific Advice to Cut #Sugar and #Alcohol
Advanced #Liver Fibrosis Is Common in Patients With Type 2 #Diabetes Followed in the Outpatient Setting: The Need for Systematic Screening
Assess the prevalence of nonalcoholic fatty liver disease (NAFLD) and of liver fibrosis associated with nonalcoholic steatohepatitis in unselected patients with type 2 diabetes mellitus (T2DM). A total of 561 patients with T2DM (age: 60 ± 11 years; BMI: 33.4 ± 6.2 kg/m2; and HbA1c: 7.5 ± 1.8%) attending primary care or endocrinology outpatient clinics… Continue reading Advanced #Liver Fibrosis Is Common in Patients With Type 2 #Diabetes Followed in the Outpatient Setting: The Need for Systematic Screening
#Baricitinib plus #Remdesivir for Hospitalized Adults with #Covid-19
Severe coronavirus disease 2019 (Covid-19) is associated with dysregulated inflammation. The effects of combination treatment with baricitinib, a Janus kinase inhibitor, plus remdesivir are not known. METHODS We conducted a double-blind, randomized, placebo-controlled trial evaluating baricitinib plus remdesivir in hospitalized adults with Covid-19. All the patients received remdesivir (≤10 days) and either baricitinib (≤14 days)… Continue reading #Baricitinib plus #Remdesivir for Hospitalized Adults with #Covid-19
Responsiveness of the PROMIS-29 Scales in Individuals With Chronic Low #Back Pain
..The PROMIS-29 questionnaire assesses seven health-related quality-of-life domains. However, research to evaluate the responsiveness and MCIDs of the PROMS-29 scores in individuals with low back pain is limited. Methods. The study was conducted in physical therapy clinics in Thailand, using validated Thai versions of the study measures. One hundred and eighty-three individuals with chronic low… Continue reading Responsiveness of the PROMIS-29 Scales in Individuals With Chronic Low #Back Pain
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