Cognitive impairment and #sedentary behavior predict health-related attrition in a prospective longitudinal #Parkinson’s disease study

In Parkinson’s disease (PD), the high burden of motor and non-motor symptoms, such as cognitive impairment or falls, is associated with rapid disease progression and mortality. This is often reflected by an increased drop-out rate of PD patients in longitudinal studies. Active physical behavior can impact the disease course beneficially and has an overall positive effect on health. Contrarily, sedentary behavior is associated with cognitive … Continue reading Cognitive impairment and #sedentary behavior predict health-related attrition in a prospective longitudinal #Parkinson’s disease study

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Effect of #caloric restriction with or without physical #activity on body composition and epicardial #fat in type 2 diabetic patients: a pilot randomized controlled trial

There is debate over the independent and combined effects of caloric restriction (CR) and physical activity (PA) on reduction in fat mass and in epicardial fat thickness. We compared the impact of a similar energy deficit prescription by CR or by CR combined with PA on total fat mass, epicardial fat thickness, and cardiometabolic profile in individuals with type 2 diabetes In this 16-week randomized … Continue reading Effect of #caloric restriction with or without physical #activity on body composition and epicardial #fat in type 2 diabetic patients: a pilot randomized controlled trial

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Inadequate #Physical Activity and #Sedentary Behavior Are Independent Predictors of Nonalcoholic Fatty #Liver Disease

In general, physical activity (PA) and nonalcoholic fatty liver disease (NAFLD) have an inverse association. However, studies assessing the impact of the widely accepted Physical Activity Guidelines for Americans (PA Guidelines) on NAFLD are lacking. We performed a serial, cross‐sectional analysis among adults by using the 2007‐2016 US National Health and Nutrition Examination Survey. NAFLD and advanced fibrosis were defined by using various noninvasive panels. … Continue reading Inadequate #Physical Activity and #Sedentary Behavior Are Independent Predictors of Nonalcoholic Fatty #Liver Disease

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Effect of time of day of recreational and household #physical activity on prostate and breast #cancer risk (MCC‐Spain study)

Experimental evidence indicates that exercise performed at different times of the day may affect circadian rhythms and circadian disruption has been linked to breast and prostate cancer. We examined in a population‐based case‐control study (MCC‐Spain) if the time‐of‐day when physical activity is done affects prostate and breast cancer risk. Lifetime recreational and household physical activity was assessed by in‐person interviews. Information on time‐of‐day of activity … Continue reading Effect of time of day of recreational and household #physical activity on prostate and breast #cancer risk (MCC‐Spain study)

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#Ageing attenuates the effect of extracellular hyperosmolality on whole‐body #heat exchange during exercise‐heat #stress

Key points In humans, hypohydration attenuates sweat secretion and attenuates whole‐body heat loss, probably to mitigate further fluid losses and thereby support blood pressure regulation. Recently, however, we demonstrated that the hypohydration‐mediated reduction in net whole‐body heat exchange (evaporative heat loss – dry heat gain) was blunted in middle‐aged compared to younger men during moderate exercise in dry heat; albeit, the underpinning mechanisms could not … Continue reading #Ageing attenuates the effect of extracellular hyperosmolality on whole‐body #heat exchange during exercise‐heat #stress

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Plasma Biomarker Concentrations Associated With Return to #Sport Following Sport-Related #Concussion in Collegiate Athletes—A Concussion Assessment, Research, and Education (CARE) Consortium Study

Identifying plasma biomarkers associated with the amount of time an athlete may need before they return to sport (RTS) following a sport-related concussion (SRC) is important because it may help to improve the health and safety of athletes.. A total of 3 plasma biomarkers (ie, total tau protein, glial fibrillary acidic protein [GFAP], and neurofilament light chain protein [Nf-L]) were measured using an ultrasensitive single … Continue reading Plasma Biomarker Concentrations Associated With Return to #Sport Following Sport-Related #Concussion in Collegiate Athletes—A Concussion Assessment, Research, and Education (CARE) Consortium Study

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Associations between abdominal #obesity indices and #diabetic complications: Chinese visceral #adiposity index and neck circumference

Obesity, especially abdominal obesity, has been considered a risk factor for diabetic complications. Many abdominal obesity indices have been established, including neck circumference (NC), waist-to-hip ratio (WHR), lipid accumulation product (LAP), visceral adiposity index (VAI) and the Chinese visceral adiposity index (CVAI). However, studies investigating the associations between these indices and diabetic complications are limited. The objective of this study was to investigate the associations … Continue reading Associations between abdominal #obesity indices and #diabetic complications: Chinese visceral #adiposity index and neck circumference

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#Hyperglycaemia is associated with impaired muscle signalling and #aerobic adaptation to exercise

Increased aerobic exercise capacity, as a result of exercise training, has important health benefits. However, some individuals are resistant to improvements in exercise capacity, probably due to undetermined genetic and environmental factors. Here, we show that exercise-induced improvements in aerobic capacity are blunted and aerobic remodelling of skeletal muscle is impaired in several animal models associated with chronic hyperglycaemia. Our data point to chronic hyperglycaemia … Continue reading #Hyperglycaemia is associated with impaired muscle signalling and #aerobic adaptation to exercise

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Does adequate physical activity attenuate the associations of alcohol and alcohol‐related cancer mortality? A pooled study of 54 686 British adults

The potential of physical activity (PA) to attenuate the effects of alcohol consumption on the risks of alcohol‐related cancer mortality is unknown. We used data from participants aged 30 years and over in 10 British population‐based surveys (Health Surveys for England 1994, 1997, 1998, 1999, 2003, 2004, 2006 and 2008 and the Scottish Health Surveys 1998 and 2003). Alcohol‐related cancer mortality included oral cavity, throat, larynx, … Continue reading Does adequate physical activity attenuate the associations of alcohol and alcohol‐related cancer mortality? A pooled study of 54 686 British adults

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Echocardiographic Characterization of Female Professional Basketball Players in the US

..Echocardiographic variables included left ventricular (LV) dimensions, wall thickness, mass, prevalence of LV hypertrophy, aortic dimensions, right ventricular (RV) dimension, and right and left atrial size. Linear regression was used to assess the associations between cardiac structure and function with body size quantified as body surface area (BSA) in the primary analysis. Results A total of 140 female athletes (mean [SD] age, 26.8 [3.9] years; … Continue reading Echocardiographic Characterization of Female Professional Basketball Players in the US

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Healthy #lifestyle and the risk of #Alzheimer dementia

Using data from the Chicago Health and Aging Project (CHAP; n = 1,845) and the Rush Memory and Aging Project (MAP; n = 920), we defined a healthy lifestyle score on the basis of nonsmoking, ≥150 min/wk moderate/vigorous-intensity physical activity, light to moderate alcohol consumption, high-quality Mediterranean-DASH Diet.. ..During a median follow-up of 5.8 years in CHAP and 6.0 years in MAP, 379 and 229 … Continue reading Healthy #lifestyle and the risk of #Alzheimer dementia

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Current and 1-Year Psychological and Physical Effects of Replacing Sedentary Time With Time in Other Behaviors

Sedentary time is inversely associated with health. Capturing 24 hours of behavior (i.e., sleep, sedentary, light physical activity, and moderate-to-vigorous physical activity) is necessary to understand behavior–health associations.. ..Cross-sectional analyses revealed substituting prolonged sedentary time for sleep was associated with lower stress (standardized β= −0.11), better mood (−0.12), and lower BMI (−0.10). Substituting total or prolonged sedentary for moderate-to-vigorous physical activity was associated with lower … Continue reading Current and 1-Year Psychological and Physical Effects of Replacing Sedentary Time With Time in Other Behaviors

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