Residential exposure to transportation #noise in Denmark and incidence of #dementia: national cohort study

To investigate the association between long term residential exposure to road traffic and railway noise and risk of incident dementia. Design Nationwide prospective register based cohort study. Setting Denmark. Participants 1 938 994 adults aged ≥60 years living in Denmark between 1 January 2004 and 31 December 2017. Main outcome measures Incident cases of all cause dementia… Continue reading Residential exposure to transportation #noise in Denmark and incidence of #dementia: national cohort study

#COVID-19 Transmission Dynamics Among Close #Contacts of Index Patients With COVID-19A Population-Based Cohort Study in Zhejiang Province, China

Much remains unknown about the transmission dynamics of COVID-19. How the severity of the index case and timing of exposure is associated with disease in close contacts of index patients with COVID-19 and clinical presentation in those developing disease is not well elucidated. Objectives To investigate the association between the timing of exposure and development… Continue reading #COVID-19 Transmission Dynamics Among Close #Contacts of Index Patients With COVID-19A Population-Based Cohort Study in Zhejiang Province, China

Association of poor #housing conditions with #COVID-19 incidence and mortality across US counties

Poor housing conditions have been linked with worse health outcomes and infectious disease spread. Since the relationship of poor housing conditions with incidence and mortality of COVID-19 is unknown, we investigated the association between poor housing condition and COVID-19 incidence and mortality in US counties. MethodsWe conducted cross-sectional analysis of county-level data from the US… Continue reading Association of poor #housing conditions with #COVID-19 incidence and mortality across US counties

#Cognitive stimulation in the workplace, plasma proteins, and risk of #dementia: three analyses of population cohort studies

To examine the association between cognitively stimulating work and subsequent risk of dementia and to identify protein pathways for this association. Design Multicohort study with three sets of analyses. Setting United Kingdom, Europe, and the United States. Participants Three associations were examined: cognitive stimulation and dementia risk in 107 896 participants from seven population based prospective… Continue reading #Cognitive stimulation in the workplace, plasma proteins, and risk of #dementia: three analyses of population cohort studies

The association between occupational #asbestos exposure with the risk of incidence and mortality from #prostate #cancer: a systematic review and meta-analysis

There is conflicting evidence on the association between asbestos exposure and prostate cancer (PCa). Two recent meta-analyses have claimed that exposure is associated with increased PCa incidence and mortality, but they suffer from some methodological flaws. Given the potential importance of this research question, we aimed to perform a methodologically sound systematic review and meta-analysis… Continue reading The association between occupational #asbestos exposure with the risk of incidence and mortality from #prostate #cancer: a systematic review and meta-analysis

Long-term night #shift work is associated with the risk of atrial #fibrillation and #coronary heart disease

The aim of this study was to test whether current and past night shift work was associated with incident atrial fibrillation (AF) and whether this association was modified by genetic vulnerability. Its associations with coronary heart disease (CHD), stroke, and heart failure (HF) were measured as a secondary aim. Methods and resultsThis cohort study included… Continue reading Long-term night #shift work is associated with the risk of atrial #fibrillation and #coronary heart disease

Environmental #Pollution: An Under-recognized Threat to Children’s Health, Especially in Low- and Middle-Income Countries

Exposures to environmental pollutants during windows of developmental vulnerability in early life can cause disease and death in infancy and childhood as well as chronic, non-communicable diseases that may manifest at any point across the life span. Patterns of pollution and pollution-related disease change as countries move through economic development. Environmental pollution is now recognized… Continue reading Environmental #Pollution: An Under-recognized Threat to Children’s Health, Especially in Low- and Middle-Income Countries

Secondary organic aerosols from anthropogenic volatile organic compounds contribute substantially to air #pollution mortality

Anthropogenic secondary organic aerosol (ASOA), formed from anthropogenic emissions of organic compounds, constitutes a substantial fraction of the mass of submicron aerosol in populated areas around the world and contributes to poor air quality and premature mortality. However, the precursor sources of ASOA are poorly understood, and there are large uncertainties in the health benefits… Continue reading Secondary organic aerosols from anthropogenic volatile organic compounds contribute substantially to air #pollution mortality

Mortality among persons who inject #drugs: A prospective cohort followed over three decades in Baltimore, Maryland, USA

Over the past decades, people who inject drugs (PWID) have been impacted by the development of combination antiretroviral therapy (cART) to combat HIV/AIDS, the prescription opioid crisis, and increased use of lethal synthetic opioids. We measured how these dynamics have impacted mortality among PWID in an urban U.S. city. DesignProspective cohort study using data from… Continue reading Mortality among persons who inject #drugs: A prospective cohort followed over three decades in Baltimore, Maryland, USA