..A small thigh circumference is associated with an increased risk of diabetes, cardiovascular diseases, and total mortality. The purpose of this study was to evaluate the association between thigh circumference and hypertension in the middle-aged and elderly population. ..Thigh circumference was negatively correlated with systolic blood pressure, diastolic blood pressure, fasting glucose, and total cholesterol.… Continue reading Large #thigh circumference is associated with lower blood #pressure in overweight and obese individuals: a community-based study
Category: Diet
#Obesity, unfavourable lifestyle and genetic risk of type 2 #diabetes: a case-cohort study
Obesity (BMI ≥ 30 kg/m2) and unfavourable lifestyle were associated with higher risk for incident type 2 diabetes regardless of genetic predisposition (p > 0.05 for GRS–obesity and GRS–lifestyle interaction). The effect of obesity on type 2 diabetes risk (HR 5.81 [95% CI 5.16, 6.55]) was high, whereas the effects of high genetic risk (HR 2.00 [95% CI 1.76,… Continue reading #Obesity, unfavourable lifestyle and genetic risk of type 2 #diabetes: a case-cohort study
Association of Birth by Cesarean Delivery With #Obesity and Type 2 #Diabetes Among Adult Women
..After 1 913 978 person-years of follow-up, 12 156 (36.6%) women were obese and 2014 (6.1%) had received a diagnosis of type 2 diabetes. Women born by cesarean delivery were more likely to be classified as obese and to have received a diagnosis of type 2 diabetes during follow-up. The multivariable-adjusted relative risk of obesity among women born… Continue reading Association of Birth by Cesarean Delivery With #Obesity and Type 2 #Diabetes Among Adult Women
Association of Healthy #Lifestyle With Years Lived Without Major Chronic Diseases
..Four baseline lifestyle factors (smoking, body mass index, physical activity, and alcohol consumption) were each allocated a score based on risk status: optimal (2 points), intermediate (1 point), or poor (0 points) resulting in an aggregated lifestyle score ranging from 0 (worst) to 8 (best). Sixteen lifestyle profiles were constructed from combinations of these risk… Continue reading Association of Healthy #Lifestyle With Years Lived Without Major Chronic Diseases
A high-#salt diet compromises antibacterial neutrophil responses through hormonal perturbation
The Western diet is rich in salt, which poses various health risks. A high-salt diet (HSD) can stimulate immunity through the nuclear factor of activated T cells 5 (Nfat5)–signaling pathway, especially in the skin, where sodium is stored. The kidney medulla also accumulates sodium to build an osmotic gradient for water conservation. Here, we studied… Continue reading A high-#salt diet compromises antibacterial neutrophil responses through hormonal perturbation
Comparison of dietary macronutrient patterns of 14 popular named dietary programmes for #weight and cardiovascular risk factor reduction in adults: systematic review and network meta-analysis of randomised trials
..Compared with usual diet, low carbohydrate and low fat diets had a similar effect at six months on weight loss (4.63 v 4.37 kg, both moderate certainty) and reduction in systolic blood pressure (5.14 mm Hg, moderate certainty v 5.05 mm Hg, low certainty) and diastolic blood pressure (3.21 v 2.85 mm Hg, both low… Continue reading Comparison of dietary macronutrient patterns of 14 popular named dietary programmes for #weight and cardiovascular risk factor reduction in adults: systematic review and network meta-analysis of randomised trials
Plant‐based and animal‐based low‐carbohydrate #diets and risk of #hepatocellular carcinoma among US men and women
Little is known about the role of low‐carbohydrate diets (LCDs) in the development of hepatocellular carcinoma (HCC).. ..During 3,664,769 person years of follow‐up, there were 156 incident HCC cases. Although there were no associations between overall or animal‐based LCD score and risk of HCC, plant‐based LCD score was inversely associated with HCC risk (HR: 0.83;… Continue reading Plant‐based and animal‐based low‐carbohydrate #diets and risk of #hepatocellular carcinoma among US men and women
Joint Effects of #Body Mass Index and Waist Circumference on the Incidence of #Hypertension in a Community-Based Chinese Population
.. During 2.3 years of follow-up, 19.1% (n = 97) of the men and 13.6% (n = 158) of the women developed incident hypertension. The adjusted odds ratios (ORs) (95% confidence intervals [CIs]) for obesity (BMI ≥30) were 3.49 (1.59–7.66) and 2.60 (1.48–4.55) for men and women, respectively. A 1-point increase in BMI was associated… Continue reading Joint Effects of #Body Mass Index and Waist Circumference on the Incidence of #Hypertension in a Community-Based Chinese Population
#Diet modulates brain network stability, a biomarker for brain #aging, in young adults
..One cohort was scanned under standard diet, overnight fasting, and ketogenic diet conditions. To isolate the impact of fuel type, an independent overnight fasted cohort was scanned before and after administration of a calorie-matched glucose and exogenous ketone ester (D-β-hydroxybutyrate) bolus. Across the life span, brain network destabilization correlated with decreased brain activity and cognitive… Continue reading #Diet modulates brain network stability, a biomarker for brain #aging, in young adults
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