..the definition of hypertension was lowered from a blood pressure (BP) of greater than or equal to 140/90 to greater than or equal to 130/80 mm Hg. The new diastolic BP threshold of 80 mm Hg was recommended based on expert opinion and changes the definition of isolated diastolic hypertension (IDH). atherosclerotic cardiovascular disease (ASCVD)… Continue reading Association of Isolated Diastolic #Hypertension as Defined by the 2017 ACC/AHA Blood Pressure Guideline With Incident Cardiovascular Outcomes
Category: Cardiology
Implications of Abnormal Exercise Electrocardiography With Normal Stress Echocardiography
..After excluding submaximal tests and nondiagnostic ECG or stress imaging results, 15 077 patients (mean [SD] age, 52 [13] years; 6228 [41.3%] men) were classified by stress test results Death occurred in 425 patients with −ECG/−Echo (4.8%), 50 patients with +ECG/−Echo (5.9%), and 70 patients with +Echo (11.2%). Myocardial infarction occurred in 195 patients with −ECG/−Echo… Continue reading Implications of Abnormal Exercise Electrocardiography With Normal Stress Echocardiography
Abdominal #obesity and the risk of recurrent atherosclerotic cardiovascular disease after myocardial #infarction
..Univariate and multivariable-adjusted Cox regression models were used to calculate hazard ratios and 95% confidence intervals in quintiles of waist circumference as well as three categories of body mass index including normal weight, overweight and obesity. Results The majority of patients had abdominal obesity. During a median follow-up time of 3.8 years, 1232 men (7.3%)… Continue reading Abdominal #obesity and the risk of recurrent atherosclerotic cardiovascular disease after myocardial #infarction
#Walnuts and Vegetable Oils Containing Oleic Acid Differentially Affect the Gut Microbiota and Associations with #Cardiovascular Risk Factors: Follow-up of a Randomized, Controlled, Feeding Trial in Adults at Risk for Cardiovascular Disease
..Forty-two adults at cardiovascular risk were included in a randomized, crossover, controlled-feeding trial that provided a 2-wk standard Western diet (SWD) run-in and three 6-wk isocaloric study diets: a diet containing whole walnuts (WD; 57–99 g/d walnuts; 2.7% ALA), a fatty acid–matched diet devoid of walnuts (walnut fatty acid–matched diet; WFMD; 2.6% ALA), and a… Continue reading #Walnuts and Vegetable Oils Containing Oleic Acid Differentially Affect the Gut Microbiota and Associations with #Cardiovascular Risk Factors: Follow-up of a Randomized, Controlled, Feeding Trial in Adults at Risk for Cardiovascular Disease
Sex Differences in Blood #Pressure Trajectories Over the Life Course
..Women compared with men exhibited a steeper increase in BP that began as early as in the third decade and continued through the life course (likelihood ratio test χ2 = 531 for systolic BP; χ2 = 123 for diastolic BP; χ2 = 325 for MAP; and χ2 = 572 for PP; P for all <.001). After adjustment for multiple cardiovascular disease risk factors,… Continue reading Sex Differences in Blood #Pressure Trajectories Over the Life Course
Associations between Serum Levels of #Cholesterol and #survival to Age 90 in Postmenopausal Women
Although elevated lipid levels predict increased risk of coronary heart disease and death in middle‐aged women and men, evidence is mixed if lipid levels measured in later life predict survival to very old ages.. HDL and LDL levels were not associated with survival to age 90 after adjustment for cardiovascular risk factors.. Similarly, no associations… Continue reading Associations between Serum Levels of #Cholesterol and #survival to Age 90 in Postmenopausal Women
Estimated #Stroke-Free Survival of #Folic Acid Therapy for Hypertensive Adults
The CSPPT (China Stroke Primary Prevention Trial) demonstrated a significant risk reduction of first stroke in hypertensive patients treated with enalapril plus folic acid compared with those with enalapril alone, but the lifetime stroke-free survival associated with the treatment is unknown.. ..Compared with enalapril alone, the enalapril plus folic acid treatment projected a mean lifetime… Continue reading Estimated #Stroke-Free Survival of #Folic Acid Therapy for Hypertensive Adults
Shared Genetic Loci Between Body #Mass Index and Major #Psychiatric Disorders A Genome-wide Association Study
People with major psychiatric disorders (MPDs) have a 10- to 20-year shorter life span than the rest of the population, and this difference is mainly due to comorbid cardiovascular diseases.. schizophrenia (SCZ), bipolar disorder (BIP), major depression (MD) body mass index (BMI) ..Of the shared loci, 34% (73 of 213) in SCZ, 52% (36 of… Continue reading Shared Genetic Loci Between Body #Mass Index and Major #Psychiatric Disorders A Genome-wide Association Study
Intensive vs Standard Blood #Pressure Control in Adults 80 Years or Older: A Secondary Analysis of the #Systolic Blood Pressure Intervention Trial
Participants with hypertension but without diabetes (N = 1167) were randomized to an SBP target below 120 mm Hg (intensive treatment) vs a target below 140 mm Hg (standard treatment).. Intensive treatment led to significant reductions in cardiovascular events (hazard ratio [HR] = .66; 95% confidence interval [CI] = .49‐.90), mortality (HR = .67; 95% CI =… Continue reading Intensive vs Standard Blood #Pressure Control in Adults 80 Years or Older: A Secondary Analysis of the #Systolic Blood Pressure Intervention Trial
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