Obstructive sleep apnea (OSA), nocturnal hypertension, and non-dipping systolic blood pressure (BP) are each highly prevalent among African Americans. However, few data are available on the association between OSA and nighttime BP in this population.. ..Among 206 participants who completed ABPM and participated in the Jackson Heart Sleep Study, 50.5% had nocturnal hypertension and 26.2%… Continue reading Association of Obstructive Sleep Apnea with Nighttime Blood Pressure in African Americans: the Jackson Heart Study
Category: Cardiology
Dose-Response Association of Low-Intensity and Nondaily Smoking With Mortality in the United States
An increasing proportion of US smokers smoke at low intensity and not every day. Some nondaily smokers have always had this pattern, whereas others previously smoked daily. The effect of reducing the level of smoking from daily to nondaily smoking and the dose response at low smoking levels are poorly understood.. ..Among 505 500 participants (aged… Continue reading Dose-Response Association of Low-Intensity and Nondaily Smoking With Mortality in the United States
#Anaemia, iron status, and gender predict the outcome in patients with chronic heart #failure
Anaemia and iron deficiency (ID) are frequently found in patients with chronic heart failure (CHF) and associated with adverse outcome. However, it is unclear whether absolute [transferrin saturation (TSAT) <20%, ferritin <100 μg/L] or inflammation‐driven functional ID (TSAT <20%, ferritin >100 μg/L) with and without anaemia had similar or different consequences for such patients Within… Continue reading #Anaemia, iron status, and gender predict the outcome in patients with chronic heart #failure
#Hypocalcaemia predicts 12‐month re‐hospitalization in heart #failure
Potential pathophysiology of heart failure with preserved ejection fraction (HFpEF) has not been fully explored. The aim of the study was to reveal the association of serum calcium concentration at baseline with 12‐month clinical outcome in the disease.. ..Multivariate COX regression analysis revealed that baseline hypocalcaemia was associated with the increased risk of cardiac re‐hospitalization… Continue reading #Hypocalcaemia predicts 12‐month re‐hospitalization in heart #failure
Clinical Outcomes With #Beta-Blocker Use in Patients With Recent History of Myocardial #Infarction
It is uncertain whether beta-blockers (BBs) are beneficial in contemporary stable patients with prior myocardial infarction (MI). Therefore, we sought to examine the effectiveness of BB use in this population.. ..We included 33,811 patients with prior MI, of whom 21,440 (63.4%) were dispensed a BB. The median age was 78 years, and 56% were male.… Continue reading Clinical Outcomes With #Beta-Blocker Use in Patients With Recent History of Myocardial #Infarction
Association of Blood Pressure Lowering With Incident #Dementia or Cognitive Impairment A Systematic Review and Meta-analysis
..The mean (SD) age of trial participants was 69 (5.4) years and 40 617 (42.2%) were women. The mean systolic baseline blood pressure was 154 (14.9) mm Hg and the mean diastolic blood pressure was 83.3 (9.9) mm Hg. The mean duration of follow-up was 49.2 months. Blood pressure lowering with antihypertensive agents compared with… Continue reading Association of Blood Pressure Lowering With Incident #Dementia or Cognitive Impairment A Systematic Review and Meta-analysis
Blood #Pressure at 6 Months after Acute Myocardial #Infarction and Outcomes at 2 Years: The Perils Associated With Excessively Low Blood Pressures
This study aimed to determine the association between achieved blood pressure at 6-month follow-up and cardiovascular outcomes at 2 years in patients treated with β-blockers and renin-angiotensin-aldosterone blockers after acute myocardial infarction (AMI).. ..Achieved blood pressures were categorized into 10-mm Hg increments. The primary outcome was all-cause death. The secondary outcome was a composite of… Continue reading Blood #Pressure at 6 Months after Acute Myocardial #Infarction and Outcomes at 2 Years: The Perils Associated With Excessively Low Blood Pressures
Effect of Cerebrovascular and/or Peripheral #Artery Disease With or Without Attainment of #Lipid Goals on Long-term Outcomes in Patients With Coronary Artery Disease
Involvement of atherosclerosis in extracardiac vascular territories may identify coronary artery disease (CAD) patients at higher risk for adverse events. We investigated the long-term prognostic implications of polyvascular disease in patients with CAD, and further analyzed lipid goal attainment and its relation to patient outcomes. The study was a retrospective analysis of 10,297 patients undergoing… Continue reading Effect of Cerebrovascular and/or Peripheral #Artery Disease With or Without Attainment of #Lipid Goals on Long-term Outcomes in Patients With Coronary Artery Disease
Association of Childhood #Psychosocial Environment With 30‐Year #Cardiovascular Disease Incidence and Mortality in Middle Age
Childhood adversity and trauma have been shown to be associated with poorer cardiovascular disease (CVD) outcomes in adulthood. However, longitudinal studies of this association are rare.. ..Participants (n=3646) completed the Childhood Family Environment (CFE) questionnaire at the year 15 (2000–2001) CARDIA examination and were grouped by high, moderate, or low relative CFE adversity scores.. ..Participants… Continue reading Association of Childhood #Psychosocial Environment With 30‐Year #Cardiovascular Disease Incidence and Mortality in Middle Age
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