..32 prospective cohort studies were included in the systematic review and 31 in the meta-analysis. During the follow-up period of 3.5 to 32 years, 113 039 deaths (16 429 from cardiovascular disease and 22 303 from cancer) occurred among 715 128 participants. Intake of total protein was associated with a lower risk of all cause mortality (pooled effect size… Continue reading Dietary intake of total, animal, and #plant #proteins and risk of all cause, cardiovascular, and cancer mortality: systematic review and dose-response meta-analysis of prospective cohort studies
Category: Cardiology
Predictors of Mortality in Patients with Chronic Heart #Failure: Is #Hyponatremia a Useful Clinical Biomarker?
Chronic heart failure (CHF) is a global health burden. Despite advances in treatment, there remain well-recognised morbidity and mortality. Risk stratification requires the identification and validation of biomarkers, old and new. Hyponatremia has re-emerged as a prognostic marker in CHF patients.. ..Mean age of patients was 60.61 ± 12.63 (SD) years; 65.1% were males, and… Continue reading Predictors of Mortality in Patients with Chronic Heart #Failure: Is #Hyponatremia a Useful Clinical Biomarker?
Age- and Weight-Adapted Dose of #Prasugrel Versus Standard Dose of #Ticagrelor in Patients With Acute #Coronary Syndromes
The efficacy and safety of a reduced dose of prasugrel versus a standard dose of ticagrelor in elderly patients or those with a low body weight presenting with an acute coronary syndrome (ACS) are unknown.. ..The efficacy and safety of a reduced dose of prasugrel versus a standard dose of ticagrelor in elderly patients or… Continue reading Age- and Weight-Adapted Dose of #Prasugrel Versus Standard Dose of #Ticagrelor in Patients With Acute #Coronary Syndromes
Acute pulmonary #embolism in patients with obstructive #sleep apnea: frequency, hospital outcomes, and recurrence
The objectives of this study were to assess the effect of obstructive sleep apnea (OSA) on the risk of acute pulmonary embolism (PE), hospital outcomes including mortality, and PE recurrence.. ..Of 25,038 patients, 3,184 (13%) had OSA and 283 (1.1%) experienced PE. Frequency of PE in patients with and without OSA was 2.4% versus 0.9%… Continue reading Acute pulmonary #embolism in patients with obstructive #sleep apnea: frequency, hospital outcomes, and recurrence
Nonalcoholic Fatty #Liver Disease and Advanced Fibrosis in US Adults Across Blood Pressure Categories
Nonalcoholic fatty liver disease (#NAFLD) is common in patients with hypertension but controversy exists as to whether screening for this condition should be performed. Here, we evaluate the prevalence of NAFLD and advanced fibrosis in US adults across blood pressure categories and estimate the number of patients who require referral to hepatologists. In this cross-sectional… Continue reading Nonalcoholic Fatty #Liver Disease and Advanced Fibrosis in US Adults Across Blood Pressure Categories
Association between #prediabetes and risk of all cause mortality and #cardiovascular disease: updated meta-analysis
To evaluate the associations between prediabetes and the risk of all cause mortality and incident cardiovascular disease in the general population and in patients with a history of atherosclerotic cardiovascular disease.. ..A total of 129 studies were included, involving 10 069 955 individuals for analysis. In the general population, prediabetes was associated with an increased risk of… Continue reading Association between #prediabetes and risk of all cause mortality and #cardiovascular disease: updated meta-analysis
The effect of caloric restriction on blood pressure and cardiovascular function: A systematic review and meta-analysis of randomized controlled trials
Preclinical evidence suggests that caloric restriction is an effective therapy for a number of cardiovascular insults. Whether caloric restriction has cardio-protective effects in humans is not well understood. The aim was to systematically review and meta-analyze human randomized control trials (RCTs) testing the effect of caloric restriction on blood pressure (BP) and cardiovascular function.. ..Thirty-two… Continue reading The effect of caloric restriction on blood pressure and cardiovascular function: A systematic review and meta-analysis of randomized controlled trials
Effect of tailoring anticoagulant treatment duration by applying a recurrence risk prediction model in patients with venous thromboembolism compared to usual care: A randomized controlled trial
Patients with unprovoked (i.e., without the presence of apparent transient risk factors such as recent surgery) venous thromboembolism (VTE) are at risk of recurrence if anticoagulants are stopped after 3–6 months, yet their risk remains heterogeneous. Thus, prolonging anticoagulant treatment should be considered in high-risk patients, whereas stopping is likely preferred in those with a… Continue reading Effect of tailoring anticoagulant treatment duration by applying a recurrence risk prediction model in patients with venous thromboembolism compared to usual care: A randomized controlled trial
Association of Statin Use With All-Cause and Cardiovascular Mortality in US Veterans 75 Years and Older
Data are limited regarding statin therapy for primary prevention of atherosclerotic cardiovascular disease (ASCVD) in adults 75 years and older.. ..Of 326 981 eligible veterans (mean [SD] age, 81.1 [4.1] years; 97% men; 91% white), 57 178 (17.5%) newly initiated statins during the study period. During a mean follow-up of 6.8 (SD, 3.9) years, a total 206 902… Continue reading Association of Statin Use With All-Cause and Cardiovascular Mortality in US Veterans 75 Years and Older
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