Category: Cardiology
#Beta-Blockers after Myocardial #Infarction and Preserved #Ejection Fraction
BACKGROUNDMost trials that have shown a benefit of beta-blocker treatment after myocardial infarction included patients with large myocardial infarctions and were conducted in an era before modern biomarker-based diagnosis of myocardial infarction and treatment with percutaneous coronary intervention, antithrombotic agents, high-intensity statins, and renin–angiotensin–aldosterone system antagonists.METHODSIn a parallel-group, open-label trial performed at 45 centers in… Continue reading #Beta-Blockers after Myocardial #Infarction and Preserved #Ejection Fraction
Impact of #Mental Health Treatment on Outcomes in Patients With #Heart Failure and Ischemic Heart Disease
BackgroundThere is conflicting evidence as to the impact of mental health treatment on outcomes in patients with heart disease. The aim of this study was to examine whether individuals who received mental health treatment for anxiety or depression after being hospitalized for ischemic disorders or heart failure had a reduced frequency of rehospitalizations, emergency department… Continue reading Impact of #Mental Health Treatment on Outcomes in Patients With #Heart Failure and Ischemic Heart Disease
Gut #microbiome and metabolome profiling in Framingham heart study reveals #cholesterol-metabolizing bacteria
Multi-omic profiling in FHS reveals microbes and metabolites associated with CVD•Oscillibacter species are associated with decreased blood and stool cholesterol•Homology searches and molecular networking predict cholesterol enzymes and products•Oscillibacter species encode for conserved cholesterol-metabolizing enzymesSummaryAccumulating evidence suggests that cardiovascular disease (CVD) is associated with an altered gut microbiome. Our understanding of the underlying mechanisms has been hindered… Continue reading Gut #microbiome and metabolome profiling in Framingham heart study reveals #cholesterol-metabolizing bacteria
Ultra-processed #food exposure and adverse health outcomes: umbrella review of epidemiological meta-analyses
AbstractObjective To evaluate the existing meta-analytic evidence of associations between exposure to ultra-processed foods, as defined by the Nova food classification system, and adverse health outcomes.Design Systematic umbrella review of existing meta-analyses.Data sources MEDLINE, PsycINFO, Embase, and the Cochrane Database of Systematic Reviews, as well as manual searches of reference lists from 2009 to June 2023.Eligibility criteria for… Continue reading Ultra-processed #food exposure and adverse health outcomes: umbrella review of epidemiological meta-analyses
Association of #glycaemic index and glycaemic load with type 2 #diabetes, #cardiovascular disease, #cancer, and all-cause mortality: a meta-analysis of mega cohorts of more than 100 000 participants
There is debate over whether the glycaemic index of foods relates to chronic disease. We aimed to assess the associations between glycaemic index (GI) and glycaemic load (GL) and type 2 diabetes, cardiovascular disease, diabetes-related cancers, and all-cause mortality.MethodsWe did a meta-analysis of large cohorts (≥100 000 participants) identified from the Richard Doll Consortium. We searched… Continue reading Association of #glycaemic index and glycaemic load with type 2 #diabetes, #cardiovascular disease, #cancer, and all-cause mortality: a meta-analysis of mega cohorts of more than 100 000 participants
A terminal metabolite of niacin promotes vascular inflammation and contributes to #cardiovascular disease risk
Despite intensive preventive cardiovascular disease (CVD) efforts, substantial residual CVD risk remains even for individuals receiving all guideline-recommended interventions. Niacin is an essential micronutrient fortified in food staples, but its role in CVD is not well understood. In this study, untargeted metabolomics analysis of fasting plasma from stable cardiac patients in a prospective discovery cohort… Continue reading A terminal metabolite of niacin promotes vascular inflammation and contributes to #cardiovascular disease risk
#Autopsy findings in cases of fatal #COVID-19 #vaccine -induced #myocarditis
COVID-19 vaccines have been linked to myocarditis, which, in some circumstances, can be fatal. This systematic review aims to investigate potential causal links between COVID-19 vaccines and death from myocarditis using post-mortem analysis. We performed a systematic review of all published autopsy reports involving COVID-19 vaccination-induced myocarditis through 3 July 2023. All autopsy studies that… Continue reading #Autopsy findings in cases of fatal #COVID-19 #vaccine -induced #myocarditis
#Statins and risks of #dementia among patients with heart failure: a population-based retrospective cohort study in Hong Kong
Heart failure (HF) and dementia frequently co-exist with shared pathological mechanisms and risk factors. Our study aims to investigate the association between statin therapy and the risks of dementia and its subtypes among patients with HF.MethodsThe Hong Kong Clinical Data Analysis and Reporting System database was interrogated to identify patients with incident HF diagnosis from… Continue reading #Statins and risks of #dementia among patients with heart failure: a population-based retrospective cohort study in Hong Kong
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