The current literature on the chronic effects of static stretching (SS) exercises on muscle strength and power is unclear and controversial.ObjectiveWe aimed to examine the chronic effects of SS exercises on muscle strength and power as well as flexibility in healthy individuals across the lifespan.DesignSystematic review with meta-analysis of (randomized) controlled trials.Data SourcesA systematic literature… Continue reading Chronic Effects of Static #Stretching Exercises on Muscle #Strength and Power in Healthy Individuals Across the Lifespan: A Systematic Review with Multi-level Meta-analysis
Author: aledopress
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Adherence to #Mediterranean diet is inversely associated with #depressive symptoms in older women: findings from the NutBrain Study
Data on the association of the Mediterranean diet with depressive symptoms in older people at high risk of depression are scarce. This study aimed to investigate the cross-sectional association of the adherence to the Mediterranean diet and its components with depressive symptoms in the Italian NutBrain cohort of older men and women. A total of… Continue reading Adherence to #Mediterranean diet is inversely associated with #depressive symptoms in older women: findings from the NutBrain Study
Association of #glycaemic index and glycaemic load with type 2 #diabetes, #cardiovascular disease, #cancer, and all-cause mortality: a meta-analysis of mega cohorts of more than 100 000 participants
There is debate over whether the glycaemic index of foods relates to chronic disease. We aimed to assess the associations between glycaemic index (GI) and glycaemic load (GL) and type 2 diabetes, cardiovascular disease, diabetes-related cancers, and all-cause mortality.MethodsWe did a meta-analysis of large cohorts (≥100 000 participants) identified from the Richard Doll Consortium. We searched… Continue reading Association of #glycaemic index and glycaemic load with type 2 #diabetes, #cardiovascular disease, #cancer, and all-cause mortality: a meta-analysis of mega cohorts of more than 100 000 participants
#Light stimulation of mitochondria reduces blood #glucose levels
Mitochondria regulate metabolism, but solar light influences its rate. Photobiomodulation (PBM) with red light (670 nm) increases mitochondrial membrane potentials and adenosine triphosphate production and may increase glucose demand. Here we show, with a glucose tolerance test, that PBM of normal subjects significantly reduces blood sugar levels. A 15 min exposure to 670 nm light reduced the degree… Continue reading #Light stimulation of mitochondria reduces blood #glucose levels
Vitamin #E intake is inversely associated with #NAFLD measured by liver ultrasound transient elastography
Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases, whose severe form is associated with oxidative stress. Vitamin E as an antioxidant has a protective potential in NAFLD. Whether dietary intake of vitamin E, supplementary vitamin E use, and total vitamin E have a preventive effect on NAFLD requires investigation.… Continue reading Vitamin #E intake is inversely associated with #NAFLD measured by liver ultrasound transient elastography
Downregulation of the kidney #glucagon receptor, essential for #renal function and systemic homeostasis, contributes to chronic kidney disease
The glucagon receptor (GCGR) in the kidney is expressed in nephron tubules. In humans and animal models with chronic kidney disease, renal GCGR expression is reduced. However, the role of kidney GCGR in normal renal function and in disease development has not been addressed. Here, we examined its role by analyzing mice with constitutive or conditional kidney-specific loss of the Gcgr. Adult renal Gcgr knockout mice exhibit metabolic dysregulation and a functional… Continue reading Downregulation of the kidney #glucagon receptor, essential for #renal function and systemic homeostasis, contributes to chronic kidney disease
A terminal metabolite of niacin promotes vascular inflammation and contributes to #cardiovascular disease risk
Despite intensive preventive cardiovascular disease (CVD) efforts, substantial residual CVD risk remains even for individuals receiving all guideline-recommended interventions. Niacin is an essential micronutrient fortified in food staples, but its role in CVD is not well understood. In this study, untargeted metabolomics analysis of fasting plasma from stable cardiac patients in a prospective discovery cohort… Continue reading A terminal metabolite of niacin promotes vascular inflammation and contributes to #cardiovascular disease risk
Effects of #mouthwash on #periodontal pathogens and glycemic control in patients with type 2 #diabetes mellitus
Periodontitis is known to be associated with type 2 diabetes mellitus (T2DM), and gargling with mouthwash is known to reduce the incidence of periodontitis by inhibiting periodontal pathogens. However, the effects of mouthwash on oral and systemic conditions in patients with T2DM remain unknown. In this study, we investigated the effects of gargling with mouthwash… Continue reading Effects of #mouthwash on #periodontal pathogens and glycemic control in patients with type 2 #diabetes mellitus
#Fasting-mimicking #diet causes hepatic and blood markers changes indicating reduced biological #age and disease risk
In mice, periodic cycles of a fasting mimicking diet (FMD) protect normal cells while killing damaged cells including cancer and autoimmune cells, reduce inflammation, promote multi-system regeneration, and extend longevity. Here, we performed secondary and exploratory analysis of blood samples from a randomized clinical trial (NCT02158897) and show that 3 FMD cycles in adult study… Continue reading #Fasting-mimicking #diet causes hepatic and blood markers changes indicating reduced biological #age and disease risk
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