Abnormal Coagulation parameters are associated with poor prognosis in patients with novel #coronavirus #pneumonia

In the recent outbreak of novel coronavirus infection in Wuhan, China, significantly abnormal coagulation parameters in severe novel coronavirus pneumonia (NCP) cases were a concern.. Conventional coagulation results and outcomes of consecutive 183 patients with confirmed NCP in Tongji hospital were retrospectively analysed. Results The overall mortality was 11.5%, the non‐survivors revealed significantly higher D‐dimer… Continue reading Abnormal Coagulation parameters are associated with poor prognosis in patients with novel #coronavirus #pneumonia

Effect of dose and duration of reduction in dietary #sodium on blood #pressure levels: systematic review and meta-analysis of randomised trials

... Each 50 mmol reduction in 24 hour sodium excretion was associated with a 1.10 mm Hg (0.66 to 1.54; P<0.001) reduction in SBP and a 0.33 mm Hg (0.04 to 0.63; P=0.03) reduction in DBP. Reductions in blood pressure were observed in diverse population subsets examined, including hypertensive and non-hypertensive individuals. For the same… Continue reading Effect of dose and duration of reduction in dietary #sodium on blood #pressure levels: systematic review and meta-analysis of randomised trials

The associations of major #foods and fibre with risks of ischaemic and haemorrhagic #stroke: a prospective study of 418 329 participants in the EPIC cohort across nine European countries

..For ischaemic stroke (4281 cases), lower risks were observed with higher consumption of fruit and vegetables combined (HR; 95% CI per 200 g/day higher intake, 0.87; 0.82–0.93, P-trend < 0.001), dietary fibre (per 10 g/day, 0.77; 0.69–0.86, P-trend < 0.001), milk (per 200 g/day, 0.95; 0.91–0.99, P-trend = 0.02), yogurt (per 100 g/day, 0.91; 0.85–0.97, P-trend = 0.004), and cheese (per 30 g/day, 0.88; 0.81–0.97, P-trend = 0.008), while higher… Continue reading The associations of major #foods and fibre with risks of ischaemic and haemorrhagic #stroke: a prospective study of 418 329 participants in the EPIC cohort across nine European countries

#Aspirin and #fracture risk: a systematic review and exploratory meta-analysis of observational studies

This review provides insights into the potential for aspirin to preserve bone mineral density (BMD) and reduce fracture risk, building knowledge of the risk-benefit profile of aspirin. ..Aspirin use was associated with a 17% lower odds for any fracture (OR 0.83, 95% CI 0.70 to 0.99; I2=71%; six studies; n=511 390). Aspirin was associated with a higher… Continue reading #Aspirin and #fracture risk: a systematic review and exploratory meta-analysis of observational studies

Age at #period cessation and trajectories of #cardiovascular risk factors across mid and later life

To examine the association between age at period cessation and trajectories of anthropometry, blood pressure, lipids and glycated haemoglobin (HbA1c) from midlife to age 69 years.. ..We found no evidence that age at period cessation was associated with trajectories of log triglyceride, LDL-C and HDL-C from 53 to 69 years and trajectories of SBP or… Continue reading Age at #period cessation and trajectories of #cardiovascular risk factors across mid and later life

#Education, Race/Ethnicity, and Causes of Premature #Mortality Among Middle-Aged Adults in 4 US Urban Communities: Results From CARDIA, 1985–2017

..Our primary outcome was years of potential life lost (YPLL). Results. The age-adjusted mortality rate per 1000 persons was 45.17 among Black men, 25.20 among White men, 17.63 among Black women, and 10.10 among White women. Homicide and AIDS were associated with the most YPLL, but cancer and cardiovascular disease were the most common causes… Continue reading #Education, Race/Ethnicity, and Causes of Premature #Mortality Among Middle-Aged Adults in 4 US Urban Communities: Results From CARDIA, 1985–2017

Association of Dual Decline in Memory and #Gait Speed With Risk for #Dementia Among Adults Older Than 60 Years

Dual decline in both memory and gait speed may characterize a group of older individuals at high risk for future dementia.. ..Participants were 60 years or older, had an initial gait speed of more than 0.6 m/s (ie, free of overt dismobility), with repeated measures of memory and gait speed before dementia diagnosis during a… Continue reading Association of Dual Decline in Memory and #Gait Speed With Risk for #Dementia Among Adults Older Than 60 Years

The association between actor/partner #optimism and #cognitive functioning among older couples

Higher optimism has been linked with health, well‐being, and cognitive functioning. Spouses also play an important role on people's health, especially in older adulthood.. ..Optimism was assessed at baseline (t1) and cognition was measured every two years with up to five repeated assessments of cognition data over the 8‐year follow‐up period (t1; t2; t3; t4;… Continue reading The association between actor/partner #optimism and #cognitive functioning among older couples