Post-reversible cerebral vasoconstriction syndrome #headache

Chronic headache may persist after the remission of reversible cerebral vasoconstriction syndrome (RCVS) in some patients. We aimed to investigate the prevalence, characteristics, risk factors, and the impact of post-RCVS headache. Methods We prospectively recruited patients with RCVS and collected their baseline demographics, including psychological distress measured by Hospital Anxiety and Depression scale. We evaluated… Continue reading Post-reversible cerebral vasoconstriction syndrome #headache

Hepatic #Histopathology Among Excessive #Drinkers Without Advanced Liver Disease

Alcohol-associated liver disease represents a spectrum of histopathological changes from steatosis to advanced fibrosis and cirrhosis. The major goals of this retrospective study were to characterize the histologic features in patients with excessive alcohol use who presented with an abnormal hepatic panel and/or abnormal radiographic imaging and did not meet the clinical diagnosis of alcoholic… Continue reading Hepatic #Histopathology Among Excessive #Drinkers Without Advanced Liver Disease

A Pilot Randomized Controlled Trial of Transcendental #Meditation as Treatment for #Posttraumatic Stress Disorder in Veterans

Preliminary studies have demonstrated the efficacy of Transcendental Meditation (TM) for treating posttraumatic stress disorder (PTSD). The present study extended previous research with a pilot trial of TM as a treatment for PTSD via a single‐blinded, randomized controlled design. veterans with PTSD (N = 40) were assigned to a TM intervention or treatment‐as‐usual (TAU) control… Continue reading A Pilot Randomized Controlled Trial of Transcendental #Meditation as Treatment for #Posttraumatic Stress Disorder in Veterans

Benzedrex (#propylhexedrine): Drug Safety Communication – FDA Warns that Abuse and Misuse of the Nasal #Decongestant Causes Serious Harm

AUDIENCE: Consumer, Patient, Health Professional, Pharmacy ISSUE: The FDA is warning that the abuse and misuse of the over-the-counter (OTC) nasal decongestant propylhexedrine can lead to serious harm such as heart and mental health problems. Some of these complications, which include fast or abnormal heart rhythm, high blood pressure, and paranoia, can lead to hospitalization,… Continue reading Benzedrex (#propylhexedrine): Drug Safety Communication – FDA Warns that Abuse and Misuse of the Nasal #Decongestant Causes Serious Harm

#Aspirin Use Is Associated With Decreased Mechanical Ventilation, Intensive Care Unit Admission, and In-Hospital Mortality in Hospitalized Patients With #Coronavirus Disease 2019

Coronavirus disease-2019 (COVID-19) is associated with hypercoagulability and increased thrombotic risk in critically ill patients. To our knowledge, no studies have evaluated whether aspirin use is associated with reduced risk of mechanical ventilation, intensive care unit (ICU) admission, and in-hospital mortality. METHODS: A retrospective, observational cohort study of adult patients admitted with COVID-19 to multiple… Continue reading #Aspirin Use Is Associated With Decreased Mechanical Ventilation, Intensive Care Unit Admission, and In-Hospital Mortality in Hospitalized Patients With #Coronavirus Disease 2019

Association of spontaneous #abortion with all cause and cause specific premature #mortality: prospective cohort study

To investigate the association of spontaneous abortion with the risk of all cause and cause specific premature mortality (death before the age of 70). Design Prospective cohort study. Setting The Nurses’ Health Study II (1993-2017), United States. Participants 101 681 ever gravid female nurses participating in the Nurses’ Health Study II. Main outcomes measures Lifetime occurrence… Continue reading Association of spontaneous #abortion with all cause and cause specific premature #mortality: prospective cohort study

OR10-1 – Efficacy of High-Intensity Intermittent #Training for Improving Cardio-Metabolic Health in Women With #Polycystic Ovary Syndrome

Polycystic ovary syndrome (PCOS) is a common and complex endocrinopathy with significant metabolic and reproductive manifestations, carrying a major health and economic burden. Consistent improvements in clinical outcomes have been reported as a result of exercise training, but shortfalls with exercise prescription are evident. Research suggests that high-intensity intermittent training (HIIT) is feasible, well tolerated… Continue reading OR10-1 – Efficacy of High-Intensity Intermittent #Training for Improving Cardio-Metabolic Health in Women With #Polycystic Ovary Syndrome

Utility of bedside leucocyte esterase testing to rule out septic #arthritis

Suspected septic arthritis is a common presentation to EDs. The underlying diagnosis is often non-infective pathology. Differentiating between aetiologies is difficult. A bedside test with high negative predictive value (NPV) may allow safe discharge of patients, reduce the time in the ED, hospital admission and associated costs. This study aims to evaluate the NPV of… Continue reading Utility of bedside leucocyte esterase testing to rule out septic #arthritis

#Semaglutide 2·4 mg once a week in adults with #overweight or #obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial

Background This trial assessed the efficacy and safety of the GLP-1 analogue once a week subcutaneous semaglutide 2·4 mg versus semaglutide 1·0 mg (the dose approved for diabetes treatment) and placebo for weight management in adults with overweight or obesity, and type 2 diabetes. Methods This double-blind, double-dummy, phase 3, superiority study enrolled adults with… Continue reading #Semaglutide 2·4 mg once a week in adults with #overweight or #obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial