Highlights•UK immunocompromised paediatric patients were at no increased risk of severe COVID-19. •Only 4/38 PCR detected infections were admitted to hospital. None had acute severe COVID-19 or died. •Increasing age and immunodeficiency increased reporting of SARS-CoV-2 infection. Worsening of fever, cough and sore throat were associated with reporting SARS-CoV-2 infection. •Serology results suggest there was… Continue reading Immunocompromised children and young people are at no increased risk of severe COVID-19
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150 Research Studies Affirm Naturally Acquired Immunity to Covid-19: Documented, Linked, and Quoted
we should not force COVID vaccines on anyone when the evidence shows that naturally acquired immunity is equal to or more robust and superior to existing vaccines. Instead, we should respect the right of the bodily integrity of individuals to decide for themselves. Public health officials and the medical establishment with the help of the… Continue reading 150 Research Studies Affirm Naturally Acquired Immunity to Covid-19: Documented, Linked, and Quoted
Association of the Gut Microbiota With Cognitive Function in Midlife
Question Is the gut microbiota associated with cognitive function? Findings In this cross-sectional study, β-diversity, a measure of gut microbial community composition, was statistically significantly associated with all measures of cognitive function. Several specific genera were also significantly associated with 1 or more measures of cognitive function after adjustment for multiple comparisons. Meaning These results… Continue reading Association of the Gut Microbiota With Cognitive Function in Midlife
Comprehensive investigations revealed consistent pathophysiological alterations after vaccination with COVID-19 vaccines
Large-scale COVID-19 vaccinations are currently underway in many countries in response to the COVID-19 pandemic. Here, we report, besides generation of neutralizing antibodies, consistent alterations in hemoglobin A1c, serum sodium and potassium levels, coagulation profiles, and renal functions in healthy volunteers after vaccination with an inactivated SARS-CoV-2 vaccine. Similar changes had also been reported in… Continue reading Comprehensive investigations revealed consistent pathophysiological alterations after vaccination with COVID-19 vaccines
Efficacy of Ceftazidime and Cefepime in the Management of COVID-19 Patients: Single Center Report from Egypt
AbstractThe purpose of this study was to explore the value of using cefepime and ceftazidime in treating patients with COVID-19. A total of 370 (162 males) patients, with RT-PCR-confirmed cases of COVID-19, were included in the study. Out of them, 260 patients were treated with cefepime or ceftazidime, with the addition of steroids to the… Continue reading Efficacy of Ceftazidime and Cefepime in the Management of COVID-19 Patients: Single Center Report from Egypt
Chronic pain precedes disrupted eating behavior in low-back pain patients
Chronic pain is associated with anhedonia and decreased motivation. These behavioral alterations have been linked to alterations in the limbic brain and could explain the increased risk for obesity in pain patients. The mechanism of these behavioral changes and how they set in in relation to the development of chronic pain remain however poorly understood.… Continue reading Chronic pain precedes disrupted eating behavior in low-back pain patients
Non-target screening for the identification of migrating compounds from reusable plastic bottles into drinking water
Highlights•Migration of > 400 plastic related and > 3500 dishwasher related compounds. •The dishwashing process increased the migration of plastic related compounds. •Oligomers suspected from polycaprolactone (PCL) were migrating. •Three of the identified photoinitiators have possible endocrine disrupting effects. •Diethyltoluamide (DEET) may have been formed from the plasticizer laurolactam. AbstractReusable plastic sports bottles are used… Continue reading Non-target screening for the identification of migrating compounds from reusable plastic bottles into drinking water
How effective are interventions to reduce Staphylococcus aureus in eczema?
Key messagesEczema is commonly colonized by Staphylococcus aureus so some advocate antibiotics or dilute bleach baths. This Cochrane review evaluated trials of anti-staph treatments in people with infected or uninfected eczema. From 41 trials (1753 participants), there was little evidence that these interventions impact eczema symptoms. ... 2.7 Authors’ conclusionsWe found insufficient evidence on the… Continue reading How effective are interventions to reduce Staphylococcus aureus in eczema?
Gut Ruminococcaceae levels at baseline correlate with risk of antibiotic-associated diarrhea
Highlights•Antibiotic-associated diarrhea (AAD) affects a significant proportion of patients•13/30 healthy volunteers who received oral amoxicillin-clavulanate developed AAD•Individuals who developed AAD had lower levels of gut Ruminococcaceae at baseline•Baseline levels of Faecalibacterium prausnitzii were predictive of risk of AAD SummaryAntibiotic-associated diarrhea (AAD) affects a significant proportion of patients receiving antibiotics. We sought to understand if differences… Continue reading Gut Ruminococcaceae levels at baseline correlate with risk of antibiotic-associated diarrhea
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