Childhood trauma and schizotypy in non-clinical samples: A systematic review and meta-analysis

The association of early life adversities and psychosis symptoms is well documented in clinical populations; however, whether this relationship also extends into subclinical psychosis remains unclear. In particular, are early life adversities associated with increased levels of schizotypal personality traits in non-clinical samples? We conducted a systematic review and meta-analysis of associations between early life… Continue reading Childhood trauma and schizotypy in non-clinical samples: A systematic review and meta-analysis

Duration of Shedding of Culturable Virus in SARS-CoV-2 Omicron (BA.1) Infection

TO THE EDITOR:The B.1.1.529 (omicron) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a shorter incubation period and a higher transmission rate than previous variants.1,2 Recently, the Centers for Disease Control and Prevention recommended shortening the strict isolation period for infected persons in non–health care settings from 10 days to 5 days after… Continue reading Duration of Shedding of Culturable Virus in SARS-CoV-2 Omicron (BA.1) Infection

Tourism as a dementia treatment based on positive psychology

AbstractNo research in tourism or medicine has addressed the potential relationship between travel and the medical treatment of dementia. Given tourism's increasingly important role in society, a cross-disciplinary team of tourism and dementia experts provide insight into the potential benefits of tourism for individuals with dementia. This conceptual effort critically reviews the tourism and dementia… Continue reading Tourism as a dementia treatment based on positive psychology

Immune boosting by B.1.1.529 (Omicron) depends on previous SARS-CoV-2 exposure

The Omicron, or Pango lineage B.1.1.529, variant of SARS-CoV-2 carries multiple spike mutations with high transmissibility and partial neutralizing antibody (nAb) escape. Vaccinated individuals show protection from severe disease, often attributed to primed cellular immunity. We investigated T and B cell immunity against B.1.1.529 in triple mRNA vaccinated healthcare workers (HCW) with different SARS-CoV-2 infection… Continue reading Immune boosting by B.1.1.529 (Omicron) depends on previous SARS-CoV-2 exposure

Creutzfeldt-Jakob Disease After the COVID-19Vaccination

Reports of neurological problems are increasing for the clinical presentation of COVID-19 The clinical presentation reported in this study seemed to be a combination of nonspecificcomplications of the systemic disease, inflammation of the cerebrovascular system, and theeffects of a direct viral infection. Creutzfeldt–Jakob disease, a spongiform encephalopathycaused by prions, is characterized by a severe neurological… Continue reading Creutzfeldt-Jakob Disease After the COVID-19Vaccination

Association of Statins for Primary Prevention of Cardiovascular Diseases With Hospitalization for COVID‐19: A Nationwide Matched Population‐Based Cohort Study

BackgroundThere is little evidence on the relationship between statin use and the risk of hospitalization attributable to COVID‐19. Methods and ResultsThe French National Healthcare Data System database was used to conduct a matched‐cohort study. For each adult aged ≥40 years receiving statins for the primary prevention of cardiovascular diseases, one nonuser was randomly selected and… Continue reading Association of Statins for Primary Prevention of Cardiovascular Diseases With Hospitalization for COVID‐19: A Nationwide Matched Population‐Based Cohort Study

Light at night in older age is associated with obesity, diabetes, and hypertension

Light at night (LAN) has been associated with negative health consequences and metabolic risk factors. Little is known about the prevalence of LAN in older adults in the U.S. and its association with cardiovascular disease (CVD) risk factors. We tested the hypothesis that LAN in older age is associated with higher prevalence of individual CVD… Continue reading Light at night in older age is associated with obesity, diabetes, and hypertension

Intramyocardial Inflammation after COVID-19 Vaccination: An Endomyocardial Biopsy-Proven Case Series

Myocarditis in response to COVID-19 vaccination has been reported since early 2021. In particular, young male individuals have been identified to exhibit an increased risk of myocardial inflammation following the administration of mRNA-based vaccines. Even though the first epidemiological analyses and numerous case reports investigated potential relationships, endomyocardial biopsy (EMB)-proven cases are limited. Here, we… Continue reading Intramyocardial Inflammation after COVID-19 Vaccination: An Endomyocardial Biopsy-Proven Case Series

Passage of exogeneous fine particles from the lung into the brain in humans and animals

There are still significant knowledge gaps in understanding the intrusion and retention of exogeneous particles into the central nervous system (CNS). Here, we uncovered various exogeneous fine particles in human cerebrospinal fluids (CSFs) and identified the ambient environmental or occupational exposure sources of these particles, including commonly found particles (e.g., Fe- and Ca-containing ones) and… Continue reading Passage of exogeneous fine particles from the lung into the brain in humans and animals