AbstractNon-caloric artificial sweeteners (NAS) are among the most widely used food additives worldwide, regularly consumed by lean and obese individuals alike. NAS consumption is considered safe and beneficial owing to their low caloric content, yet supporting scientific data remain sparse and controversial. Here we demonstrate that consumption of commonly used NAS formulations drives the development… Continue reading Artificial sweeteners induce glucose intolerance by altering the gut microbiota
Author: aledopress
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Higher protein intake during caloric restriction improves diet quality and attenuates loss of lean body mass
ObjectiveHigher protein intake during weight loss is associated with better health outcomes, but whether this is because of improved diet quality is not known. The purpose of this study was to examine how the change in self-selected protein intake during caloric restriction (CR) alters diet quality and lean body mass (LBM). MethodsIn this analysis of… Continue reading Higher protein intake during caloric restriction improves diet quality and attenuates loss of lean body mass
Effects of non-nutritive (artificial vs natural) sweeteners on 24-h glucose profiles
Replacing nutritive sweetener with non-nutritive sweeteners (NNS) has the potential to improve glycaemic control. The objective of this study was to investigate the effects of consuming artificial NNS (that is, aspartame), natural NNS (that is, monk fruit and stevia), and sucrose-sweetened beverages on 24-h glucose profiles. Ten healthy males took part in this randomised, crossover… Continue reading Effects of non-nutritive (artificial vs natural) sweeteners on 24-h glucose profiles
Western-style Diet, pks Island-Carrying Escherichia coli, and Colorectal Cancer: Analyses from Two Large Prospective Cohort Studies
BACKGROUND AND AIMSEvidence supports a carcinogenic role of Escherichia coli carrying the polyketide synthase (pks) island that encodes enzymes for colibactin biosynthesis. We hypothesized that the association of western-style diet (rich in red and processed meat) with colorectal cancer incidence might be stronger for tumors containing higher amounts of pks+ E. coli.METHODSWestern diet score was… Continue reading Western-style Diet, pks Island-Carrying Escherichia coli, and Colorectal Cancer: Analyses from Two Large Prospective Cohort Studies
The decline of COVID-19 severity and lethality over two years of pandemic
Undernotification of SARS-CoV-2 infections has been a major obstacle to the tracking of critical quantities such as infection attack rates and the probability of severe and lethal outcomes. We use a model of SARS-CoV-2 transmission and vaccination informed by epidemiological and genomic surveillance data to estimate the number of daily infections occurred in Italy in… Continue reading The decline of COVID-19 severity and lethality over two years of pandemic
Incidence of New-Onset Type 2 Diabetes After Cancer: A Danish Cohort Study
For patients with cancer, prevalent type 2 diabetes at the date of cancer diagnosis is associated with increased cancer-specific and all-cause mortality (1,2). Yet, despite potential health implications, there is limited knowledge on whether cancer is also a risk factor for type 2 diabetes. Moreover, the impact of new-onset type 2 diabetes after cancer diagnosis… Continue reading Incidence of New-Onset Type 2 Diabetes After Cancer: A Danish Cohort Study
Cannabis use and risks of respiratory and all-cause morbidity and mortality: a population-based, data-linkage, cohort study
Introduction Although cannabis is frequently used worldwide, its impact on respiratory health is characterised by controversy. Objective To evaluate the association between cannabis use and respiratory-related emergency room (ER) visits and hospitalisations. Methods A retrospective, population-based, cohort study was carried out, linking health survey and health administrative data for residents of Ontario, Canada, aged 12–65… Continue reading Cannabis use and risks of respiratory and all-cause morbidity and mortality: a population-based, data-linkage, cohort study
Cognitive Behavioral Therapy for Veterans With Comorbid Posttraumatic Headache and Posttraumatic Stress Disorder SymptomsA Randomized Clinical Trial
Importance Posttraumatic headache is the most disabling complication of mild traumatic brain injury. Posttraumatic stress disorder (PTSD) symptoms are often comorbid with posttraumatic headache, and there are no established treatments for this comorbidity. Objective To compare cognitive behavioral therapies (CBTs) for headache and PTSD with treatment per usual (TPU) for posttraumatic headache attributable to mild… Continue reading Cognitive Behavioral Therapy for Veterans With Comorbid Posttraumatic Headache and Posttraumatic Stress Disorder SymptomsA Randomized Clinical Trial
Effectiveness of BNT162b2 vaccine against SARS-CoV-2 infection and severe COVID-19 in children aged 5–11 years in Italy: a retrospective analysis of January–April, 2022
BackgroundBy April 13, 2022, more than 4 months after the approval of BNT162b2 (Pfizer–BioNTech) for children, less than 40% of 5–11-year-olds in Italy had been vaccinated against COVID-19. Estimating how effective vaccination is in 5–11-year-olds in the current epidemiological context dominated by the omicron variant (B.1.1.529) is important to inform public health bodies in defining… Continue reading Effectiveness of BNT162b2 vaccine against SARS-CoV-2 infection and severe COVID-19 in children aged 5–11 years in Italy: a retrospective analysis of January–April, 2022
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