Associations of Chronic #Insomnia, Longitudinal #Cognitive Outcomes, Amyloid-PET, and White Matter Changes in Cognitively Normal Older Adults

The relationship between insomnia and cognitive decline is poorly understood. We investigated associations between chronic insomnia, longitudinal cognitive outcomes, and brain health in older adults.MethodsFrom the population-based Mayo Clinic Study of Aging, we identified cognitively unimpaired older adults with or without a diagnosis of chronic insomnia who underwent annual neuropsychological assessments (z-scored global cognitive scores… Continue reading Associations of Chronic #Insomnia, Longitudinal #Cognitive Outcomes, Amyloid-PET, and White Matter Changes in Cognitively Normal Older Adults

Effects of various #exercise interventions in #insomnia patients: a systematic review and network meta-analysis

Objectives To compare the effectiveness of different exercise interventions in improving sleep quality and alleviating insomnia severity among patients with insomnia.Design Our study design was a systematic review and network meta-analysis.Eligibility criteria Our study eligibility criteria was restricted to include randomised controlled trials (RCTs) involving adults with insomnia that evaluated exercise-based interventions.Data sources PubMed, Cochrane… Continue reading Effects of various #exercise interventions in #insomnia patients: a systematic review and network meta-analysis

Impact of different types of physical #exercise on sleep quality in older population with #insomnia: a systematic review and network meta-analysis of randomised controlled trials

Objective To measure the impact of each type of exercise on sleep quality and identify the exercise that enhances sleep quality the most.Study selection Eligible randomised controlled trials that compare physical exercise to routine activities, usual care, non-physical activity, or health education to measure the Pittsburgh Sleep Quality Index.Data source Studies retrieved from Medline, Embase,… Continue reading Impact of different types of physical #exercise on sleep quality in older population with #insomnia: a systematic review and network meta-analysis of randomised controlled trials

Incidence of adverse #cardiovascular events in patients with #insomnia: A systematic review and meta-analysis of real-world data

Insomnia is a prevalent sleeping disorder associated with increasing cardiovascular (CV) mortality and morbidity. However, data incorporating recent clinical studies evaluating these outcomes is scarce. Hence, we aimed to investigate the association of insomnia with CV mortality, myocardial infarction (MI), all-cause mortality, and incidence of CV disease by conducting the first-ever meta-analysis of real-world data… Continue reading Incidence of adverse #cardiovascular events in patients with #insomnia: A systematic review and meta-analysis of real-world data

Music to improve sleep quality in adults with depression-related insomnia (MUSTAFI): randomized controlled trial

Background Insomnia in depression is common and difficult to resolve. Unresolved depression-related sleep disturbances increase risk of relapse at high costs for individuals and society. Trials have suggested music for insomnia in various populations, but there is little research on the effectiveness of music for depression-related insomnia. Methods We examined the efficacy of a music… Continue reading Music to improve sleep quality in adults with depression-related insomnia (MUSTAFI): randomized controlled trial

Association between insomnia and the incidence of myocardial infarction: A systematic review and meta-analysis

BackgroundInsomnia has been closely associated with cardiovascular disease (CVD) including myocardial infarction (MI). Our study aims to assess the eligibility of insomnia as a potential risk factor for MI.MethodsPubMed, Scopus, and Web of Science were searched using terms; such as “Insomnia” and “MI.” Only observational controlled studies with data on the incidence of MI among… Continue reading Association between insomnia and the incidence of myocardial infarction: A systematic review and meta-analysis

Race Differences in the Association Between Sleep Medication Use and Risk of Dementia

Abstract: Background:The effect of sleep medications on cognition in older adults is controversial, possibly dependent upon sleep quality, and may differ by race. Objective:To determine the longitudinal association between sleep medication use and incident dementia over 15 years, and to explore whether the association is independent of nighttime sleep disturbances and if it differs by race.… Continue reading Race Differences in the Association Between Sleep Medication Use and Risk of Dementia

Effect of Telephone #Cognitive Behavioral Therapy for Insomnia in Older Adults With #Osteoarthritis Pain

Scalable delivery models of cognitive behavioral therapy for insomnia (CBT-I), an effective treatment, are needed for widespread implementation, particularly in rural and underserved populations lacking ready access to insomnia treatment. Objective To evaluate the effectiveness of telephone CBT-I vs education-only control (EOC) in older adults with moderate to severe osteoarthritis pain. Design, Setting, and Participants… Continue reading Effect of Telephone #Cognitive Behavioral Therapy for Insomnia in Older Adults With #Osteoarthritis Pain

An atlas on risk factors for type 2 #diabetes: a wide-angled Mendelian randomisation study

..We found evidence of causal associations between 34 exposures (19 risk factors and 15 protective factors) and type 2 diabetes. Insomnia was identified as a novel risk factor (OR 1.17 [95% CI 1.11, 1.23]). The other 18 risk factors were depression, systolic BP, smoking initiation, lifetime smoking, coffee (caffeine) consumption, plasma isoleucine, valine and leucine,… Continue reading An atlas on risk factors for type 2 #diabetes: a wide-angled Mendelian randomisation study