Coronavirus disease 2019 was for the first time reported in December 2019 in China, and has since spread throughout the world as a pandemic. In this point of view, we aim to discuss the occurrence of central nervous system symptomatology, and delirium, in patients suffering coronavirus disease 2019. To date, most of the research done… Continue reading #Delirium In Severe Acute Respiratory Syndrome- #Coronavirus -2 Infection: A Point Of View
An Immunomodulatory Therapeutic #Vaccine Targeting Oligomeric #Amyloid-β
Background:Aging is considered the most important risk factor for Alzheimer’s disease (AD). Recent research supports the theory that immunotherapy targeting the “oligomeric” forms of amyloid-β (Aβ) may halt the progression of AD. However, previous clinical trial of the vaccine against Aβ, called AN1792, was suspended due to cases of meningoencephalitis in patients. Objective:To develop a… Continue reading An Immunomodulatory Therapeutic #Vaccine Targeting Oligomeric #Amyloid-β
#SARS-CoV-2 seroprevalence and #transmission risk factors among high-risk close contacts: a retrospective cohort study
The proportion of asymptomatic carriers and transmission risk factors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among household and non-household contacts remains unclear. In Singapore, extensive contact tracing by the Ministry of Health for every diagnosed COVID-19 case, and legally enforced quarantine and intensive health surveillance of close contacts provided a rare opportunity to… Continue reading #SARS-CoV-2 seroprevalence and #transmission risk factors among high-risk close contacts: a retrospective cohort study
The Efficacy and Safety of Vitamin #C for Iron Supplementation in Adult Patients With Iron Deficiency #Anemia
It remains uncertain whether vitamin C routinely used with oral iron supplements is essential for patients with iron deficiency anemia (IDA).. ..The primary outcome was the change in hemoglobin level from baseline to 2 weeks of treatment, and an equivalence margin of 1 g/dL in hemoglobin was chosen for the demonstration of comparable efficacy. Secondary… Continue reading The Efficacy and Safety of Vitamin #C for Iron Supplementation in Adult Patients With Iron Deficiency #Anemia
#Dietary Inflammatory Potential and Risk of #Cardiovascular Disease Among Men and Women in the U.S.
Inflammation plays an important role in cardiovascular disease (CVD) development. Diet modulates inflammation; however, it remains unknown whether dietary patterns with higher inflammatory potential are associated with long-term CVD risk We prospectively followed 74,578 women from the Nurses’ Health Study (NHS) (1984–2016), 91,656 women from the NHSII (1991–2015), and 43,911 men from the Health Professionals… Continue reading #Dietary Inflammatory Potential and Risk of #Cardiovascular Disease Among Men and Women in the U.S.
Five-Year Patterns of #Diabetic #Retinopathy Progression in US Clinical Practice
To characterize the natural course of diabetic retinopathy (DR) in contemporary clinical practice. Patients and Methods: This was a retrospective analysis of US claims data collected between January 1, 2006, and April 30, 2017. Patients aged ≥ 18 years with continuous medical and prescription insurance coverage for 18 months before DR diagnosis (index date) and… Continue reading Five-Year Patterns of #Diabetic #Retinopathy Progression in US Clinical Practice
#Prothrombotic autoantibodies in serum from patients hospitalized with #COVID-19
Patients with COVID-19 are at high risk for thrombotic arterial and venous occlusions. Lung histopathology often reveals fibrin-based occlusions in the small blood vessels of patients who succumb to the disease. Antiphospholipid syndrome is an acquired and potentially life-threatening thrombophilia in which patients develop pathogenic autoantibodies targeting phospholipids and phospholipid-binding proteins (aPL antibodies). Case series… Continue reading #Prothrombotic autoantibodies in serum from patients hospitalized with #COVID-19
Losing Control: #Sleep Deprivation Impairs the Suppression of Unwanted #Thoughts
Unwanted memories often enter conscious awareness when individuals confront reminders. People vary widely in their talents at suppressing such memory intrusions; however, the factors that govern suppression ability are poorly understood. We tested the hypothesis that successful memory control requires sleep. Following overnight sleep or total sleep deprivation, participants attempted to suppress intrusions of emotionally… Continue reading Losing Control: #Sleep Deprivation Impairs the Suppression of Unwanted #Thoughts
Association between Neu5Gc carbohydrate and serum antibodies against it provides the molecular link to #cancer: French NutriNet-Santé study
High consumption of red and processed meat is commonly associated with increased cancer risk, particularly colorectal cancer. Antibodies against the red meat-derived carbohydrate N-glycolylneuraminic acid (Neu5Gc) exacerbate cancer in “human-like” mice. Human anti-Neu5Gc IgG and red meat are both independently proposed to increase cancer risk, yet how diet affects these antibodies is largely unknown.. ..We… Continue reading Association between Neu5Gc carbohydrate and serum antibodies against it provides the molecular link to #cancer: French NutriNet-Santé study
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