AbstractBackgroundIt remains unclear whether non–animal-derived dietary protein sources (and therefore vegan diets) can support resistance training-induced skeletal muscle remodeling to the same extent as animal-derived protein sources.MethodsIn Phase 1, 16 healthy young adults (m = 8, f = 8; age: 23 ± 1 y; BMI: 23 ± 1 kg/m2) completed a 3-d dietary intervention (high… Continue reading Vegan and Omnivorous High Protein Diets Support Comparable Daily Myofibrillar Protein Synthesis Rates and Skeletal Muscle Hypertrophy in Young Adults
Music to improve sleep quality in adults with depression-related insomnia (MUSTAFI): randomized controlled trial
Background Insomnia in depression is common and difficult to resolve. Unresolved depression-related sleep disturbances increase risk of relapse at high costs for individuals and society. Trials have suggested music for insomnia in various populations, but there is little research on the effectiveness of music for depression-related insomnia. Methods We examined the efficacy of a music… Continue reading Music to improve sleep quality in adults with depression-related insomnia (MUSTAFI): randomized controlled trial
Association of Daily Step Patterns With Mortality in US Adults
Importance Previous studies have shown that individuals who regularly walk, particularly 8000 daily steps or more, experience lower mortality. However, little is known about the health benefits of walking intensively only a few days a week.Objective To evaluate the dose-response association between the number of days an individual takes 8000 steps or more and mortality… Continue reading Association of Daily Step Patterns With Mortality in US Adults
META-ANALYSIS: CLUSTER HEADACHE, MIGRAINE HAVE STRONG LINKS TO CIRCADIAN SYSTEM
...For cluster headache, the meta-analysis found a circadian pattern of headache attacks in 71% of people. Attacks peaked in the late hours of the night to early hours of the morning. During the year, people had more attacks in the spring and fall. On the genetic level, cluster headache was associated with two main circadian… Continue reading META-ANALYSIS: CLUSTER HEADACHE, MIGRAINE HAVE STRONG LINKS TO CIRCADIAN SYSTEM
Using source-associated mobile genetic elements to identify zoonotic extraintestinal E. coli infections
Highlights•Meat may be an important vehicle for human exposure to extraintestinal pathogenic E. coli strains from food animals.•We present a novel approach for predicting the origins of clinical E. coli isolates.•Approximately 8% of the clinical E. coli isolates in our population appeared to be foodborne zoonotic strains.•Foodborne zoonotic E. coli strains were associated with asymptomatic… Continue reading Using source-associated mobile genetic elements to identify zoonotic extraintestinal E. coli infections
Dietary magnesium intake is related to larger brain volumes and lower white matter lesions with notable sex differences
PurposeTo examine the association between dietary magnesium (Mg) intake and brain volumes and white matter lesions (WMLs) in middle to early old age.MethodsParticipants (aged 40–73 years) from UK Biobank (n = 6001) were included and stratified by sex. Dietary Mg was measured using an online computerised 24 h recall questionnaire to estimate daily Mg intake. Latent class… Continue reading Dietary magnesium intake is related to larger brain volumes and lower white matter lesions with notable sex differences
Physical exercise for people with Parkinson’s disease: a systematic review and network meta‐analysis
Physical exercise is effective in managing Parkinson's disease (PD), but the relative benefit of different exercise types remains unclear.ObjectivesTo compare the effects of different types of physical exercise in adults with PD on the severity of motor signs, quality of life (QoL), and the occurrence of adverse events, and to generate a clinically meaningful treatment… Continue reading Physical exercise for people with Parkinson’s disease: a systematic review and network meta‐analysis
Long-Term Effect of Weight Regain Following Behavioral Weight Management Programs on Cardiometabolic Disease Incidence and Risk: Systematic Review and Meta-Analysis
AbstractBACKGROUND:Behavioral weight management programs (BWMPs) enhance weight loss in the short term, but longer term cardiometabolic effects are uncertain as weight is commonly regained. We assessed the impact of weight regain after BWMPs on cardiovascular risk factors, diabetes, and cardiovascular disease.METHODS:Trial registries, 11 databases, and forward-citation searching (latest search, December 19) were used to identify… Continue reading Long-Term Effect of Weight Regain Following Behavioral Weight Management Programs on Cardiometabolic Disease Incidence and Risk: Systematic Review and Meta-Analysis
C-reactive protein partially mediates the inverse association between coffee consumption and risk of type 2 diabetes: The UK Biobank and the Rotterdam study cohorts
BackgroundCoffee is among the most consumed beverages worldwide. Coffee consumption has been associated with lower risk of type 2 diabetes mellitus (T2D), but underlying mechanisms are not well understood. We aimed to study the role of classic and novel-T2D biomarkers with anti- or pro-inflammatory activity in the association between habitual coffee intake and T2D risk.… Continue reading C-reactive protein partially mediates the inverse association between coffee consumption and risk of type 2 diabetes: The UK Biobank and the Rotterdam study cohorts