Rationale: Sleep disorders are associated with hypertension and diabetes, primary risk factors for cardiovascular diseases and mortality. It is important to understand these associations in Hispanics/Latinos, in whom cardiovascular death is the leading cause of mortality. Objectives: To investigate the prospective associations of sleep disordered breathing (SDB) and insomnia with incident hypertension and diabetes among… Continue reading Associations of #Sleep Disordered #Breathing and Insomnia with Incident #Hypertension and #Diabetes: The Hispanic Community Health Study/Study of Latinos
Category: Pneumology
Interstitial #lung abnormalities and the clinical course in patients with #COPD
The presence and progression of interstitial lung abnormalities (ILA) is known to be associated with a decline of lung function and increased risk of mortality. Research question We aimed to elucidate the clinical course according to ILA in patients with chronic obstructive pulmonary disease (COPD).. ..Of 363 patients with COPD, 44 and 103 patients had… Continue reading Interstitial #lung abnormalities and the clinical course in patients with #COPD
American Academy of Pediatrics – Section on Pediatric #Pulmonology and #Sleep Medicine
1. Avoid stepping up asthma therapy (adding new drugs or going to higher doses) before assessing adherence, appropriateness of device, and technique with current asthma medications. 2. Do not use LABA/steroid combination drugs as initial therapy for intermittent or mild persistent asthma. 3. Avoid administering nebulized medications by “blow by,” or placing the mask or… Continue reading American Academy of Pediatrics – Section on Pediatric #Pulmonology and #Sleep Medicine
Effectiveness of #honey for symptomatic relief in upper #respiratory tract infections: a systematic review and meta-analysis
Antibiotic over prescription for upper respiratory tract infections (URTIs) in primary care exacerbates antimicrobial resistance. There is a need for effective alternatives to antibiotic prescribing. Honey is a lay remedy for URTIs, and has an emerging evidence base for its use. Honey has antimicrobial properties, and guidelines recommended honey for acute cough in children.. ..We… Continue reading Effectiveness of #honey for symptomatic relief in upper #respiratory tract infections: a systematic review and meta-analysis
Reducing #Antibiotic Prescribing in Primary Care for #Respiratory Illness
One-third of outpatient antibiotic prescriptions for pediatric acute respiratory tract infections (ARTIs) are inappropriate. We evaluated a distance learning program’s effectiveness for reducing outpatient antibiotic prescribing for ARTI visits.. In this stepped-wedge clinical trial run from November 2015 to June 2018, we randomly assigned 19 pediatric practices belonging to the Pediatric Research in Office Settings… Continue reading Reducing #Antibiotic Prescribing in Primary Care for #Respiratory Illness
Factors associated with #sleep disturbance in patients with chronic #obstructive pulmonary disease
Poor sleep quality in patients with chronic obstructive pulmonary disease (#COPD ) has been associated with poor health outcomes. However, there is a lack of research on factors associated with sleep disturbance in patients with COPD.. This was a prospective, multicenter cross‐sectional study enrolling a sample of 245 COPD subjects. All patients completed the patient‐reported… Continue reading Factors associated with #sleep disturbance in patients with chronic #obstructive pulmonary disease
Sex-specific associations between #erythrocyte measures and obstructive #sleep apnea
STUDY OBJECTIVES:Hypoxemic effects of obstructive sleep apnea (OSA) have been implicated in changes in erythropoiesis and hence erythrocyte measures. Sex differences are evident in both OSA and erythropoiesis. Whether sex modulates the relationship between severity of OSA and erythrocyte measures has not previously been studied.. ..RESULTS:In multiple regression models, we found significant interactions between sex… Continue reading Sex-specific associations between #erythrocyte measures and obstructive #sleep apnea
Acute pulmonary #embolism in patients with obstructive #sleep apnea: frequency, hospital outcomes, and recurrence
The objectives of this study were to assess the effect of obstructive sleep apnea (OSA) on the risk of acute pulmonary embolism (PE), hospital outcomes including mortality, and PE recurrence.. ..Of 25,038 patients, 3,184 (13%) had OSA and 283 (1.1%) experienced PE. Frequency of PE in patients with and without OSA was 2.4% versus 0.9%… Continue reading Acute pulmonary #embolism in patients with obstructive #sleep apnea: frequency, hospital outcomes, and recurrence
Initiating Pharmacologic Treatment in #Tobacco-Dependent Adults. An Official American Thoracic Society Clinical Practice Guideline
Current tobacco treatment guidelines have established the efficacy of available interventions, but they do not provide detailed guidance for common implementation questions frequently faced in the clinic. An evidence-based guideline was created that addresses several pharmacotherapy-initiation questions that routinely confront treatment teams.. ..The guideline panel formulated five strong recommendations and two conditional recommendations regarding pharmacotherapy… Continue reading Initiating Pharmacologic Treatment in #Tobacco-Dependent Adults. An Official American Thoracic Society Clinical Practice Guideline
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