Highlights•Modifications of behavior and inflammatory factors in mice gut-brain axis.•Key role of gut microbiota during the different developmental phases of ASD.•Fecal microbiota transplant improves ASD symptoms.AbstractAutism spectrum disorder (ASD) is a neurodevelopmental disorder displaying the modification of complex human behaviors, characterized by social interaction impairments, stereotypical/repetitive activities and emotional dysregulation. In this study, fecal microbiota… Continue reading Modifications of Behavior and Inflammation in Mice Following Transplant with Fecal Microbiota from Children with Autism
Category: Neurology
Laparoscopically Confirmed Endometriosis and Risk of Incident Stroke: A Prospective Cohort Study
AbstractBackground:Prior research suggests that women with endometriosis are at greater risk of coronary heart disease. Therefore, our objective was to prospectively investigate the association between laparoscopically confirmed endometriosis and risk of incident stroke during 28 years of follow-up.Methods:Participants in the NHSII cohort study (Nurses’ Health Study II) were followed from 1989 when they were between… Continue reading Laparoscopically Confirmed Endometriosis and Risk of Incident Stroke: A Prospective Cohort Study
Acute Disseminated Encephalomyelitis After SARS-CoV-2 Vaccination
BACKGROUND: Acute disseminated encephalomyelitis (ADEM) is a disorder of the central nervous system which has been associated with preceding infection as well as vaccinations. We present a case of a 61-year-old woman with ADEM after receiving her initial vaccination for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This case highlights management of this acute… Continue reading Acute Disseminated Encephalomyelitis After SARS-CoV-2 Vaccination
The Periodontal Pathogen Fusobacterium nucleatum Exacerbates Alzheimer’s Pathogenesis via Specific Pathways
Alzheimer’s Disease (AD) is the most common form of dementia in older adults and has a devastating impact on the patient’s quality of life, which creates a significant socio-economic burden for the affected individuals and their families. In recent years, studies have identified a relationship between periodontitis and AD. Periodontitis is an infectious/inflammatory disease that… Continue reading The Periodontal Pathogen Fusobacterium nucleatum Exacerbates Alzheimer’s Pathogenesis via Specific Pathways
Acute ischemic stroke and vaccine-induced immune thrombotic thrombocytopenia post COVID-19 vaccination; a systematic review
AbstractIntroductionOne of the rare but potentially serious side effects of COVID-19 vaccination is arterial and venous thrombosis. Acute ischemic stroke (AIS) cases have been reported post COVID-19 vaccination. Herein, we systematically reviewed the reported cases of AIS after COVID-19 vaccination.MethodThis systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses… Continue reading Acute ischemic stroke and vaccine-induced immune thrombotic thrombocytopenia post COVID-19 vaccination; a systematic review
Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer’s disease among women
Variants in the tau gene (MAPT) region are associated with breast cancer in women and Alzheimer's disease (AD) among persons lacking apolipoprotein E ε4 (ε4–). MethodsTo identify novel genes associated with tau-related pathology, we conducted two genome-wide association studies (GWAS) for AD, one among 10,340 ε4– women in the Alzheimer's Disease Genetics Consortium (ADGC) and… Continue reading Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer’s disease among women
Tourism as a dementia treatment based on positive psychology
AbstractNo research in tourism or medicine has addressed the potential relationship between travel and the medical treatment of dementia. Given tourism's increasingly important role in society, a cross-disciplinary team of tourism and dementia experts provide insight into the potential benefits of tourism for individuals with dementia. This conceptual effort critically reviews the tourism and dementia… Continue reading Tourism as a dementia treatment based on positive psychology
Creutzfeldt-Jakob Disease After the COVID-19Vaccination
Reports of neurological problems are increasing for the clinical presentation of COVID-19 The clinical presentation reported in this study seemed to be a combination of nonspecificcomplications of the systemic disease, inflammation of the cerebrovascular system, and theeffects of a direct viral infection. Creutzfeldt–Jakob disease, a spongiform encephalopathycaused by prions, is characterized by a severe neurological… Continue reading Creutzfeldt-Jakob Disease After the COVID-19Vaccination
Passage of exogeneous fine particles from the lung into the brain in humans and animals
There are still significant knowledge gaps in understanding the intrusion and retention of exogeneous particles into the central nervous system (CNS). Here, we uncovered various exogeneous fine particles in human cerebrospinal fluids (CSFs) and identified the ambient environmental or occupational exposure sources of these particles, including commonly found particles (e.g., Fe- and Ca-containing ones) and… Continue reading Passage of exogeneous fine particles from the lung into the brain in humans and animals
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