Ten-Hour Time-Restricted Eating Reduces Weight, Blood Pressure, and Atherogenic Lipids in Patients with #Metabolic Syndrome

In animal models, time-restricted feeding (TRF) can prevent and reverse aspects of metabolic diseases. Time-restricted eating (TRE) in human pilot studies reduces the risks of metabolic diseases in otherwise healthy individuals... ..In a single-arm, paired-sample trial, 19 participants with metabolic syndrome and a baseline mean daily eating window of ≥14 h, the majority of whom… Continue reading Ten-Hour Time-Restricted Eating Reduces Weight, Blood Pressure, and Atherogenic Lipids in Patients with #Metabolic Syndrome

Application of non-HDL #cholesterol for population-based #cardiovascular risk stratification: results from the Multinational Cardiovascular Risk Consortium

..Incidence curve analyses showed progressively higher 30-year cardiovascular disease event-rates for increasing non-HDL cholesterol categories (from 7·7% for non-HDL cholesterol <2·6 mmol/L to 33·7% for ≥5·7 mmol/L in women and from 12·8% to 43·6% in men; p<0·0001). Multivariable adjusted Cox models with non-HDL cholesterol lower than 2·6 mmol/L as reference showed an increase in the… Continue reading Application of non-HDL #cholesterol for population-based #cardiovascular risk stratification: results from the Multinational Cardiovascular Risk Consortium

Rising rural body-mass index is the main driver of the global #obesity epidemic in adults

Body-mass index (#BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities1,2. This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity.. ..We show that, contrary to the dominant paradigm,… Continue reading Rising rural body-mass index is the main driver of the global #obesity epidemic in adults

Drinking Water #Salinity, Urinary Macro‐Mineral Excretions, and Blood #Pressure in the Southwest Coastal Population of Bangladesh

Sodium (Na+) in saline water may increase blood pressure (BP), but potassium (K+), calcium (Ca2+), and magnesium (Mg2+) may lower BP. We assessed the association between drinking water salinity and population BP.. ..fresh water (electrical conductivity, <0.7 mS/cm), mild salinity (electrical conductivity ≥0.7 and <2 mS/cm), and moderate salinity (electrical conductivity ≥2 and <10 mS/cm)..… Continue reading Drinking Water #Salinity, Urinary Macro‐Mineral Excretions, and Blood #Pressure in the Southwest Coastal Population of Bangladesh

A Review of the In Vivo Evidence Investigating the Role of #Nitrite Exposure from Processed Meat Consumption in the Development of Colorectal #cancer

..The World Cancer Research Fund (WCRF) 2007 stated that the consumption of processed meat is a convincing cause of colorectal cancer (CRC), and therefore, the public should avoid it entirely. Sodium nitrite has emerged as a putative candidate responsible for the CRC-inducing effects of processed meats. Sodium nitrite is purported to prevent the growth of… Continue reading A Review of the In Vivo Evidence Investigating the Role of #Nitrite Exposure from Processed Meat Consumption in the Development of Colorectal #cancer

Clustering of #lifestyle risk factors for non-communicable diseases in 304,779 #adolescents from 89 countries: A global perspective

The precursors of non-communicable diseases (NCDs) are often manifested during childhood and adolescence with little knowledge about co-occurrence of their related lifestyle risk factors. .. ..Adolescents aged 16–17 years, compared to those aged 11–13 years, had higher odds (OR 1.33; 95% CI 1.31–1.36) of reporting ≥3 risk factors. Risk factors clustered in multiple combinations and… Continue reading Clustering of #lifestyle risk factors for non-communicable diseases in 304,779 #adolescents from 89 countries: A global perspective

The Effect of #Macronutrients on #Reproductive Hormones in Overweight and Obese Men: A Pilot Study

..Hypogonadal obese men find it difficult to lose weight. We investigated whether the modification of macronutrient intake can alter testosterone levels independently of the body mass index. Fasted overweight or obese fertile men were asked to consume meals of polyunsaturated fats (PUFA), monounsaturated fats (MUFA), refined carbohydrates (CHO, orange juice, OJ), whey and egg albumin… Continue reading The Effect of #Macronutrients on #Reproductive Hormones in Overweight and Obese Men: A Pilot Study

Body #mass index, diet, physical inactivity, and the incidence of #dementia in 1 million UK women

..Fifteen years after the baseline survey, only 1% were lost to follow-up, and 89% remained alive with no detected dementia, of whom 18,695 had dementia detected later, at a mean age of 77 (SD 4) years. Dementia detection during years 15+ was associated with baseline obesity (BMI 30+ vs 20–24 kg/m2: RR 1.21, 95% confidence… Continue reading Body #mass index, diet, physical inactivity, and the incidence of #dementia in 1 million UK women