..A previous meta-analysis of prospective studies published in 2013 showed that higher concentrations of LDL-C were associated with lower risk of hemorrhagic stroke. ..The results showed that a 10 mg/dL increase in LDL-C was associated with 3% lower risk of hemorrhagic stroke (pooled relative risk [RR] 0.97, 95% confidence interval [CI] 0.95–0.98). The association appeared… Continue reading Low-Density #Lipoprotein Cholesterol and Risk of Hemorrhagic #stroke: a Systematic Review and Dose-Response Meta-analysis of Prospective Studies
Category: Diet
Safety and efficacy of high-dose unfractionated #heparin versus high-dose enoxaparin for venous #thromboembolism prevention in morbidly obese hospitalized patients
..A single-center retrospective observational study was conducted in morbidly obese (body mass index ≥ 40 kg/m2) hospitalized patients who received either high-fixed dose enoxaparin (40 mg every 12 hours) or unfractionated heparin (7,500 units every 8 hours) for venous thromboembolism prophylaxis. ..In the 305 patients included (n=190 unfractionated heparin, n=115 enoxaparin), the incidence of major… Continue reading Safety and efficacy of high-dose unfractionated #heparin versus high-dose enoxaparin for venous #thromboembolism prevention in morbidly obese hospitalized patients
Sustained #weight loss and risk of #breast cancer in women ≥50 years: a pooled analysis of prospective data
..Compared with women with stable weight (± 2kg), women with sustained weight loss had a lower risk of breast cancer. This risk reduction was linear and specific to women not using postmenopausal hormones (>2-4.5kg lost: Hazard Ratio (HR)= 0.82, 95% confidence interval (CI): 0.70-0.96; >4.5-<9kg lost: HR = 0.75, 95% CI: 0.63-0.90; ≥9kg lost: HR = 0.68, 95% CI:… Continue reading Sustained #weight loss and risk of #breast cancer in women ≥50 years: a pooled analysis of prospective data
Evidence for a Direct Harmful Effect of #Alcohol on #Myocardial Health: A Large Cross‐Sectional Study of Consumption Patterns and Cardiovascular Disease Risk Biomarkers From Northwest Russia, 2015 to 2017
..Measurements were made of the following: (1) high‐sensitivity cardiac troponin T, (2) NT‐proBNP (N‐terminal pro‐B‐type natriuretic peptide), and (3) hsCRP (high‐sensitivity C‐reactive protein). The narcology clinic subsample had the most extreme drinking pattern and the highest levels of all 3 biomarkers relative to nonproblem drinkers in the general population: high‐sensitivity cardiac troponin T was elevated… Continue reading Evidence for a Direct Harmful Effect of #Alcohol on #Myocardial Health: A Large Cross‐Sectional Study of Consumption Patterns and Cardiovascular Disease Risk Biomarkers From Northwest Russia, 2015 to 2017
#Chili Pepper Consumption and Mortality in Italian Adults
..Over a median follow-up of 8.2 years, a total of 1,236 deaths were ascertained. Multivariable hazard ratios (HRs) for all-cause and cardiovascular disease (CVD) mortality among participants in the regular (>4 times/week) relative to none/rare intake were 0.77 (95% confidence interval [CI]: 0.66 to 0.90) and 0.66 (95% CI: 0.50 to 0.86), respectively. Regular intake… Continue reading #Chili Pepper Consumption and Mortality in Italian Adults
#Ultraprocessed Food Consumption and Risk of Type 2 #Diabetes Among Participants of the NutriNet-Santé Prospective Cohort
Ultraprocessed foods (UPF) are widespread in Western diets.. ..Absolute T2D rates in the lowest and highest UPF consumers were 113 and 166 per 100 000 person-years, respectively. Consumption of UPF was associated with a higher risk of T2D (multi-adjusted hazard ratio [HR] for an absolute increment of 10 in the percentage of UPF in the diet,… Continue reading #Ultraprocessed Food Consumption and Risk of Type 2 #Diabetes Among Participants of the NutriNet-Santé Prospective Cohort
Reduction in Glycated Hemoglobin and Daily Insulin Dose Alongside Circadian Clock Upregulation in Patients With Type 2 #Diabetes Consuming a Three- #Meal Diet: A Randomized Clinical Trial
In type 2 diabetes, insulin resistance and progressive β-cell failure require treatment with high insulin doses, leading to weight gain. Our aim was to study whether a three-meal diet (3Mdiet) with a carbohydrate-rich breakfast may upregulate clock gene expression and, as a result, allow dose reduction of insulin, leading to weight loss and better glycemic… Continue reading Reduction in Glycated Hemoglobin and Daily Insulin Dose Alongside Circadian Clock Upregulation in Patients With Type 2 #Diabetes Consuming a Three- #Meal Diet: A Randomized Clinical Trial
Association between #dairy product consumption and #hyperuricemia in an elderly population with metabolic syndrome
The prevalence of hyperuricemia has increased substantially in recent decades. It has been suggested that it is an independent risk factor for weight gain, hypertension, hypertriglyceridemia, metabolic syndrome (#MetS), and cardiovascular disease.. ..Participants in the upper quartile of the consumption of total dairy products (multiadjusted prevalence ratio (PR) = 0.84; 95% CI: 0.75–0.94; P-trend 0.02),… Continue reading Association between #dairy product consumption and #hyperuricemia in an elderly population with metabolic syndrome
The relationship between #social media use and disordered #eating in young adolescents
The relationship between social media (SM) use and disordered eating (DE) has not been adequately explored in young adolescents ..DE behaviors were reported by 51.7% of girls and 45.0% of boys, with strict exercise and meal skipping the most common. A total of 75.4% of girls and 69.9% of boys had at least one SM… Continue reading The relationship between #social media use and disordered #eating in young adolescents
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