..we tested if calculated serum osmolarity (Sosm) and adequate intake (AI) of water among women (n = 1271) and men (n = 1235) ≥ 60 years old were associated with scores of immediate and delayed recall, verbal fluency, and attention/processing speed. Sosm was categorized as < 285 (hyperhydrated), 285–289, 290–294, 295–300, or > 300 (dehydrated) mmol/L. AI of water was defined as ≥ 2 L/day for women… Continue reading #cognitive performance in relation to #hydration status and water intake among older adults, NHANES 2011–2014
Category: Diet
Hepatic Lipoprotein Export and Remission of Human Type 2 #Diabetes after #Weight Loss
..Liver fat, VLDL1-triglyceride production, and intra-pancreatic fat decreased after weight loss and remained normalized after 24 months of remission. First-phase insulin response remained increased only in those maintaining diabetes remission. Compared with those in remission at 24 months, individuals who relapsed after initial remission had a greater rise in the content of VLDL1-triglyceride and VLDL1-palmitic… Continue reading Hepatic Lipoprotein Export and Remission of Human Type 2 #Diabetes after #Weight Loss
#Caffeine, but not other phytochemicals, in mate tea (Ilex paraguariensis St. Hilaire) attenuates high-fat-high-#sucrose-diet-driven lipogenesis and body #fat accumulation
The objective was to examine the effectiveness of mate tea (MT, Ilex paraguariensis St. Hilaire) and caffeine from mate tea (MC) on in vitro lipid accumulation and in vivo diet-driven-obesity.. ..MC reduced lipid accumulation (41%) via downregulation of fatty acid synthase (Fasn) (39%) in 3T3-L1 adipocytes. Rats fed a high-fat-high-sucrose-diet and 0.1% of caffeine from… Continue reading #Caffeine, but not other phytochemicals, in mate tea (Ilex paraguariensis St. Hilaire) attenuates high-fat-high-#sucrose-diet-driven lipogenesis and body #fat accumulation
#Protein Intake Greater than the RDA Differentially Influences Whole-Body Lean #Mass Responses to Purposeful Catabolic and Anabolic Stressors: A Systematic Review and Meta-analysis
Under stressful conditions such as energy restriction (ER) and physical activity, the RDA for protein of 0.8 g · kg−1 · d−1 may no longer be an appropriate recommendation. Under catabolic or anabolic conditions, higher protein intakes are proposed to attenuate the loss or increase the gain of whole-body lean mass, respectively.. ..Among all comparisons,… Continue reading #Protein Intake Greater than the RDA Differentially Influences Whole-Body Lean #Mass Responses to Purposeful Catabolic and Anabolic Stressors: A Systematic Review and Meta-analysis
Whole #milk compared with reduced-fat milk and childhood #overweight: a systematic review and meta-analysis
The majority of children in North America consume cow-milk daily. Children aged >2 y are recommended to consume reduced-fat (0.1–2%) cow-milk to lower the risk of obesity.. ..In 18 studies, higher cow-milk fat consumption was associated with lower child adiposity, and 10 studies did not identify an association. Meta-analysis included 14 of the 28 studies… Continue reading Whole #milk compared with reduced-fat milk and childhood #overweight: a systematic review and meta-analysis
Ten-Hour Time-Restricted Eating Reduces Weight, Blood Pressure, and Atherogenic Lipids in Patients with #Metabolic Syndrome
In animal models, time-restricted feeding (TRF) can prevent and reverse aspects of metabolic diseases. Time-restricted eating (TRE) in human pilot studies reduces the risks of metabolic diseases in otherwise healthy individuals... ..In a single-arm, paired-sample trial, 19 participants with metabolic syndrome and a baseline mean daily eating window of ≥14 h, the majority of whom… Continue reading Ten-Hour Time-Restricted Eating Reduces Weight, Blood Pressure, and Atherogenic Lipids in Patients with #Metabolic Syndrome
Application of non-HDL #cholesterol for population-based #cardiovascular risk stratification: results from the Multinational Cardiovascular Risk Consortium
..Incidence curve analyses showed progressively higher 30-year cardiovascular disease event-rates for increasing non-HDL cholesterol categories (from 7·7% for non-HDL cholesterol <2·6 mmol/L to 33·7% for ≥5·7 mmol/L in women and from 12·8% to 43·6% in men; p<0·0001). Multivariable adjusted Cox models with non-HDL cholesterol lower than 2·6 mmol/L as reference showed an increase in the… Continue reading Application of non-HDL #cholesterol for population-based #cardiovascular risk stratification: results from the Multinational Cardiovascular Risk Consortium
Rising rural body-mass index is the main driver of the global #obesity epidemic in adults
Body-mass index (#BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities1,2. This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity.. ..We show that, contrary to the dominant paradigm,… Continue reading Rising rural body-mass index is the main driver of the global #obesity epidemic in adults
Effects of Intermittent #Fasting on Health, Aging, and Disease
Evidence is accumulating that eating in a 6-hour period and fasting for 18 hours can trigger a metabolic switch from glucose-based to #ketone-based energy, with increased stress resistance, increased longevity, and a decreased incidence of diseases, including cancer and obesity. https://bit.ly/369Na9v
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