Association Between #Automotive Assembly Plant Closures and #Opioid Overdose Mortality in the United States

..Automotive assembly plant closures are culturally significant events that substantially erode local economic opportunities. ..Automotive assembly plant closures were associated with statistically significant increases in opioid overdose mortality. Five years after a plant closure, mortality rates had increased by 8.6 opioid overdose deaths per 100 000 individuals (95% CI, 2.6-14.6; P = .006) in exposed counties compared with… Continue reading Association Between #Automotive Assembly Plant Closures and #Opioid Overdose Mortality in the United States

#Protein Intake Greater than the RDA Differentially Influences Whole-Body Lean #Mass Responses to Purposeful Catabolic and Anabolic Stressors: A Systematic Review and Meta-analysis

Under stressful conditions such as energy restriction (ER) and physical activity, the RDA for protein of 0.8 g · kg−1 · d−1 may no longer be an appropriate recommendation. Under catabolic or anabolic conditions, higher protein intakes are proposed to attenuate the loss or increase the gain of whole-body lean mass, respectively.. ..Among all comparisons,… Continue reading #Protein Intake Greater than the RDA Differentially Influences Whole-Body Lean #Mass Responses to Purposeful Catabolic and Anabolic Stressors: A Systematic Review and Meta-analysis

Whole #milk compared with reduced-fat milk and childhood #overweight: a systematic review and meta-analysis

The majority of children in North America consume cow-milk daily. Children aged >2 y are recommended to consume reduced-fat (0.1–2%) cow-milk to lower the risk of obesity.. ..In 18 studies, higher cow-milk fat consumption was associated with lower child adiposity, and 10 studies did not identify an association. Meta-analysis included 14 of the 28 studies… Continue reading Whole #milk compared with reduced-fat milk and childhood #overweight: a systematic review and meta-analysis

Amount and Intensity of Leisure-Time #Physical Activity and Lower #Cancer Risk

To determine whether recommended amounts of leisure-time physical activity (ie, 7.5-15 metabolic equivalent task [MET] hours/week) are associated with lower cancer risk.. ..Engagement in recommended amounts of activity (7.5-15 MET hours/week) was associated with a statistically significant lower risk of 7 of the 15 cancer types studied, including colon (8%-14% lower risk in men), breast… Continue reading Amount and Intensity of Leisure-Time #Physical Activity and Lower #Cancer Risk

Long-term benefit of #Microbiota Transfer Therapy on #autism symptoms and gut microbiota

Many studies have reported abnormal gut microbiota in individuals with Autism Spectrum Disorders (ASD), suggesting a link between gut microbiome and autism-like behaviors. Modifying the gut microbiome is a potential route to improve gastrointestinal (GI) and behavioral symptoms in children with ASD, and fecal microbiota transplant could transform the dysbiotic gut microbiome toward a healthy… Continue reading Long-term benefit of #Microbiota Transfer Therapy on #autism symptoms and gut microbiota

#Mindfulness-Based Blood #Pressure Reduction (MB-BP): Stage 1 single-arm clinical trial

..Several determinants of hypertension were improved in participants not adhering to American Heart Association guidelines at baseline, including physical activity (p = 0.02), Dietary Approaches to Stop Hypertension-consistent diet (p<0.001), and alcohol consumption (p<0.001). Findings demonstrated mean 6.1 mmHg reduction in SBP (p = 0.008) at one year follow-up; effects were most pronounced in Stage… Continue reading #Mindfulness-Based Blood #Pressure Reduction (MB-BP): Stage 1 single-arm clinical trial

Prevalence of Human #Papillomavirus Infection by Number of Vaccine Doses Among US Women

..Compared with unvaccinated women (prevalence of 12.5% [95% CI, 9.7%-15.3%]), infection with HPV type 6, 11, 16, or 18 was significantly less prevalent among women who received 1 dose (2.4% [95% CI, 0%-4.9%]), 2 doses (5.1% [95% CI, 0.8%-9.5%]), or 3 doses (3.1% [95% CI, 0.9%-5.3%]) of HPV vaccine (Table 1). There was no significant… Continue reading Prevalence of Human #Papillomavirus Infection by Number of Vaccine Doses Among US Women

Ten-Hour Time-Restricted Eating Reduces Weight, Blood Pressure, and Atherogenic Lipids in Patients with #Metabolic Syndrome

In animal models, time-restricted feeding (TRF) can prevent and reverse aspects of metabolic diseases. Time-restricted eating (TRE) in human pilot studies reduces the risks of metabolic diseases in otherwise healthy individuals... ..In a single-arm, paired-sample trial, 19 participants with metabolic syndrome and a baseline mean daily eating window of ≥14 h, the majority of whom… Continue reading Ten-Hour Time-Restricted Eating Reduces Weight, Blood Pressure, and Atherogenic Lipids in Patients with #Metabolic Syndrome