Although obesity is a well-recognised risk factor for cardiovascular disease (CVD), the impact of long-term body mass index (BMI) changes in overweight or obese adults, on the risk of heart failure, CVD and mortality has not been quantified. MethodsThis population-based cohort study used routine UK primary care electronic health data linked to secondary care and… Continue reading Long-term body mass index changes in #overweight and #obese adults and the risk of heart failure, #cardiovascular disease and mortality: a cohort study of over 260,000 adults in the UK
Tag: Obese
#Obesity and Responsiveness to #Food Marketing Before and After #Bariatric Surgery
Although food marketing is often accused of increasing population obesity, the relationship between individual responsiveness to marketing and obesity has yet to be established: Are people with obesity more responsive to food marketing and, if so, is it a stable trait or can it be reversed by bariatric surgery? We studied the responses to three… Continue reading #Obesity and Responsiveness to #Food Marketing Before and After #Bariatric Surgery
The Value of Total #Knee Replacement in Patients With Knee #Osteoarthritis and a Body Mass Index of 40 kg/m2 or Greater A Cost-Effectiveness Analysis
Total knee replacement (TKR) is an effective and cost-effective strategy for treating end-stage knee osteoarthritis. Greater risk for complications among TKR recipients with a body mass index (BMI) of 40 kg/m2 or greater has raised concerns about the value of TKR in this population. Objective: To assess the value of TKR in recipients with a… Continue reading The Value of Total #Knee Replacement in Patients With Knee #Osteoarthritis and a Body Mass Index of 40 kg/m2 or Greater A Cost-Effectiveness Analysis
Association between #obesity with pattern and length of #menstrual cycle: The role of metabolic and hormonal markers
To evaluate in a sample of Chilean adult women, the association between adiposity markers with pattern and length of the menstrual cycle, assessing the influence of metabolic markers and hormones in this relationship. Study design We conducted a cross-sectional study involving 401 premenopausal women belonging to the DERCAM study (Determinants of Breast Cancer Risk) from… Continue reading Association between #obesity with pattern and length of #menstrual cycle: The role of metabolic and hormonal markers
Self- Monitoring via Digital Health in #Weight Loss Interventions: A Systematic Review Among Adults with Overweight or #Obesity
Objective: Self- monitoring is a core component of behavioral obesity treatment, but it is unknown how digital health has been used for self- monitoring, what engagement rates are achieved in these interven-tions, and how self- monitoring and weight loss are related. Methods: This systematic review examined digital self- monitoring in behavioral weight loss interventions among… Continue reading Self- Monitoring via Digital Health in #Weight Loss Interventions: A Systematic Review Among Adults with Overweight or #Obesity
Once-Weekly #Semaglutide in Adults with Overweight or #Obesity
Obesity is a global health challenge with few pharmacologic options. Whether adults with obesity can achieve weight loss with once-weekly semaglutide at a dose of 2.4 mg as an adjunct to lifestyle intervention has not been confirmed. METHODS In this double-blind trial, we enrolled 1961 adults with a body-mass index (the weight in kilograms divided… Continue reading Once-Weekly #Semaglutide in Adults with Overweight or #Obesity
Effects of two personalized #dietary strategies during a 2‐year intervention in subjects with nonalcoholic #fatty #liver disease: a randomized trial
Background and objectives Nonalcoholic fatty liver disease (NAFLD) management is focused on lifestyle modifications, but long‐term maintenance is a challenge for many individuals. This study aimed to evaluate the long‐term effects of two personalized energy‐restricted dietary strategies on weight loss, metabolic and hepatic outcomes in overweight/obese subjects with NAFLD. Methods Ninety‐eight subjects from the Fatty… Continue reading Effects of two personalized #dietary strategies during a 2‐year intervention in subjects with nonalcoholic #fatty #liver disease: a randomized trial
#Adipose saturation reduces #lipotoxic systemic inflammation and explains the #obesity paradox
Obesity sometimes seems protective in disease. This obesity paradox is predominantly described in reports from the Western Hemisphere during acute illnesses. Since adipose triglyceride composition corresponds to long-term dietary patterns, we performed a meta-analysis modeling the effect of obesity on severity of acute pancreatitis, in the context of dietary patterns of the countries from which… Continue reading #Adipose saturation reduces #lipotoxic systemic inflammation and explains the #obesity paradox
Childhood Daily #Energy Expenditure Does Not Decrease with Market Integration and Is Not Related to #Adiposity in Amazonia
Childhood overweight and obesity (OW/OB) is increasingly centered in low- and middle-income countries (LMICs) as rural populations experience market integration and lifeway change. Most explanatory studies have relied on imprecise estimates of children's energy expenditure, restricting understanding of the relative effects of changes in diet and energy expenditure on the development of OW/OB in transitioning… Continue reading Childhood Daily #Energy Expenditure Does Not Decrease with Market Integration and Is Not Related to #Adiposity in Amazonia