Cytokine signature for predicting new-onset prediabetes after acute pancreatitis: A prospective longitudinal cohort study

Highlights•Interleukin-1β at baseline predicts new-onset prediabetes after acute pancreatitis. •Interferon γ at baseline predicts new-onset prediabetes after pancreatitis. •Changes in adaptive immunity may underlie glucose derangements after pancreatitis. AbstractBackground/purposeAcute inflammation of the pancreas often leads to metabolic sequelae, the most common of which is new-onset prediabetes (and, ultimately, diabetes). However, there is a lack of …

Continue reading Cytokine signature for predicting new-onset prediabetes after acute pancreatitis: A prospective longitudinal cohort study

#Adipose saturation reduces #lipotoxic systemic inflammation and explains the #obesity paradox

Obesity sometimes seems protective in disease. This obesity paradox is predominantly described in reports from the Western Hemisphere during acute illnesses. Since adipose triglyceride composition corresponds to long-term dietary patterns, we performed a meta-analysis modeling the effect of obesity on severity of acute pancreatitis, in the context of dietary patterns of the countries from which …

Continue reading #Adipose saturation reduces #lipotoxic systemic inflammation and explains the #obesity paradox