Objective To examine the associations between the number of days per week achieving various daily step thresholds and all-cause mortality and cardiovascular disease (CVD) incidence in older women.Methods We conducted a prospective cohort study of 13 547 women free of CVD and cancer (mean age 71.8 years). We included participants who wore an ActiGraph GT3X+ accelerometer for… Continue reading Association between frequency of meeting daily step thresholds and all-cause #mortality and #cardiovascular disease in older women
Tag: Exercise
Comparative efficacy and safety of #exercise modalities in #knee #osteoarthritis: systematic review and network meta-analysis
Objective To assess the efficacy and safety of various exercise modalities as therapeutic interventions for managing knee osteoarthritis.Design Systematic review with network meta-analysis.Data sources PubMed, Embase, Cochrane Library, Web of Science, CINAHL, PsycINFO, AMED, PEDro, Scopus, ClinicalTrials.gov, ICTRP, and ClinicalTrialsRegister.eu from database inception to August 2024.Eligibility criteria for selecting studies Randomised controlled trials comparing different… Continue reading Comparative efficacy and safety of #exercise modalities in #knee #osteoarthritis: systematic review and network meta-analysis
Effect of #exercise snacks on fitness and #cardiometabolic health in physically inactive individuals: systematic review and meta-analysis
Objectives To evaluate the effects of brief bouts of exercise spread throughout the day, termed ‘exercise snacks’, on cardiorespiratory and muscular fitness, and cardiometabolic health outcomes in physically inactive adults and older adults (aged ≥65 years).Design Systematic review and meta-analysis.Data sources Seven databases were searched from inception to April 2025.Eligibility criteria Randomised controlled trials (RCTs)… Continue reading Effect of #exercise snacks on fitness and #cardiometabolic health in physically inactive individuals: systematic review and meta-analysis
Effects of various #exercise interventions in #insomnia patients: a systematic review and network meta-analysis
Objectives To compare the effectiveness of different exercise interventions in improving sleep quality and alleviating insomnia severity among patients with insomnia.Design Our study design was a systematic review and network meta-analysis.Eligibility criteria Our study eligibility criteria was restricted to include randomised controlled trials (RCTs) involving adults with insomnia that evaluated exercise-based interventions.Data sources PubMed, Cochrane… Continue reading Effects of various #exercise interventions in #insomnia patients: a systematic review and network meta-analysis
Structured #Exercise after Adjuvant Chemotherapy for #Colon #Cancer
Preclinical and observational studies suggest that exercise may improve cancer outcomes. However, definitive level 1 evidence is lacking.MethodsIn this phase 3, randomized trial conducted at 55 centers, we assigned patients with resected colon cancer who had completed adjuvant chemotherapy to participate in a structured exercise program (exercise group) or to receive health-education materials alone (health-education… Continue reading Structured #Exercise after Adjuvant Chemotherapy for #Colon #Cancer
#Sedentary Behavior and #Cardiac Events and Mortality After Hospitalization for Acute #Coronary Syndrome Symptoms: A Prospective Study
Patients hospitalized with symptoms of acute coronary syndrome remain at high risk for adverse events postdischarge, highlighting a need for modifiable therapeutic targets. The role of sedentary behavior in this risk and the potential benefits of replacing sedentary time with other activities remain unclear. This study examined the association between sedentary behavior and 1-year cardiac… Continue reading #Sedentary Behavior and #Cardiac Events and Mortality After Hospitalization for Acute #Coronary Syndrome Symptoms: A Prospective Study
Rest #Activity Rhythms and their Association with #Cardiorespiratory Fitness and #Walking Energetics in #Older Adults: Study of Muscle, #Mobility and #Aging
Purpose It is recognized that disruptions in circadian behavior, such as with shift work or jet lag, are associated with diminished health. This known relationship implies that people with stronger indices of circadian behavior will exhibit improved physiology. To address the association between rhythmic activity behavior and physiology we proposed that metrics indicative of ‘more… Continue reading Rest #Activity Rhythms and their Association with #Cardiorespiratory Fitness and #Walking Energetics in #Older Adults: Study of Muscle, #Mobility and #Aging
#Exercise without Weight Loss Prevents Seasonal Decline in Vitamin #D Metabolites: The VitaDEx Randomized Controlled Trial
Many adults become vitamin D deficient or insufficient during winter at northerly latitudes when cutaneous vitamin D synthesis does not occur. Vitamin D accumulates in adipose tissue and people with overweight or obesity are more likely to have low systemic vitamin D. This randomized controlled trial demonstrates that regular exercise completely maintains serum concentrations of… Continue reading #Exercise without Weight Loss Prevents Seasonal Decline in Vitamin #D Metabolites: The VitaDEx Randomized Controlled Trial
Individual and additive effects of vitamin #D, #omega-3 and #exercise on DNA methylation clocks of biological aging in older adults from the DO-HEALTH trial
While observational studies and small pilot trials suggest that vitamin D, omega-3 and exercise may slow biological aging, larger clinical trials testing these treatments individually or in combination are lacking. Here, we report the results of a post hoc analysis among 777 participants of the DO-HEALTH trial on the effect of vitamin D (2,000 IU per… Continue reading Individual and additive effects of vitamin #D, #omega-3 and #exercise on DNA methylation clocks of biological aging in older adults from the DO-HEALTH trial
2 Medical News 