We assessed, for the first time, to what extent the composition of the gut microbiome might explain the cross-sectional association of habitual flavonoid and flavonoid-rich food intake with systolic and diastolic blood pressure (BP) in a community-based sample (N=904) from Northern Germany. Gut microbiome composition was sequenced from 16S ribosomal RNA genes. Higher total flavonoid… Continue reading Microbial Diversity and Abundance of Parabacteroides Mediate the Associations Between Higher Intake of #Flavonoid-Rich Foods and Lower Blood #Pressure
Tag: Diet
#Meal composition during an ad libitum buffet meal and longitudinal predictions of #weight and percent body fat change: The role of hyper-palatable, energy dense, and ultra-processed foods
Foods that increase obesity risk are ubiquitous in the US food environment. Such foods may be the target of hedonic eating, which may facilitate weight gain and lead to obesity. The study tested whether meal composition during an ad libitum buffet meal was associated with 1-year weight and percent body fat changes among healthy younger… Continue reading #Meal composition during an ad libitum buffet meal and longitudinal predictions of #weight and percent body fat change: The role of hyper-palatable, energy dense, and ultra-processed foods
The #sulfur microbial diet is associated with increased risk of early-onset #colorectal cancer precursors
Diet may contribute to the increasing incidence of colorectal cancer (CRC) before age 50 (early-onset CRC). Microbial metabolism of dietary sulfur produces hydrogen sulfide (H2S), a gastrointestinal carcinogen that cannot be easily measured at scale. As a result, evidence supporting its role in early neoplasia is lacking. MethodsWe evaluated long-term adherence to the sulfur microbial… Continue reading The #sulfur microbial diet is associated with increased risk of early-onset #colorectal cancer precursors
#Time-restricted feeding protects the blood #pressure circadian rhythm in #diabetic mice
The quantity and quality of food intake have been considered crucial for peoples' wellness. Only recently has it become appreciated that the timing of food intake is also critical. Nondipping blood pressure (BP) is prevalent in diabetic patients and is associated with increased cardiovascular events. However, the causes and mechanisms of nondipping BP in diabetes… Continue reading #Time-restricted feeding protects the blood #pressure circadian rhythm in #diabetic mice
A Systematic Review of Dietary #Supplements and Alternative Therapies for #Weight Loss
Dietary supplements and alternative therapies are commercialized as a panacea for obesity/weight gain as a result of the minimal regulatory requirements in demonstrating efficacy. These products may indirectly undermine the value of guideline-driven obesity treatments. Included in this study is a systematic review of the literature of purported dietary supplements and alternative therapies for weight… Continue reading A Systematic Review of Dietary #Supplements and Alternative Therapies for #Weight Loss
Prevalence of increased #transaminases and its association with sex, age, and #metabolic parameters in children and adolescents wit7h obesity – a nationwide cross-sectional cohort study
Childhood obesity increases the risk of non-alcoholic fatty liver disease marked by elevated alanine aminotransferase (ALT). This study investigated the prevalence of increased ALT in children and adolescents with obesity, and its associations with sex, age, degree of obesity, and metabolic parameters. MethodsIndividuals between 5 and 17.99 years of age enrolled in the Swedish Childhood Obesity… Continue reading Prevalence of increased #transaminases and its association with sex, age, and #metabolic parameters in children and adolescents wit7h obesity – a nationwide cross-sectional cohort study
#Antihypertensive medication needs and blood pressure control with weight loss in the #Diabetes Remission Clinical Trial (DiRECT)
Our aim was to evaluate the safety and efficacy of a planned therapeutic withdrawal of all antihypertensive and diuretic medications, on commencing a formula low-energy diet replacement, targeting remission of type 2 diabetes. MethodsPost hoc analysis of changes in BP, antihypertensive medication prescriptions and symptoms during the initial total diet replacement phase was performed in… Continue reading #Antihypertensive medication needs and blood pressure control with weight loss in the #Diabetes Remission Clinical Trial (DiRECT)
Indices of #Diet Quality and Risk of Lung #Cancer in the Women’s Health Initiative Observational Study
Prospective evidence on associations between diet quality indices and lung cancer risk is limited, particularly among older women. ObjectivesWe investigated associations between 4 diet quality indices [Healthy Eating Index-2015 (HEI-2015), Alternate Healthy Eating Index 2010 (AHEI-2010), alternate Mediterranean Diet (aMED), and Dietary Approaches to Stop Hypertension (DASH)] and lung cancer incidence and mortality in the… Continue reading Indices of #Diet Quality and Risk of Lung #Cancer in the Women’s Health Initiative Observational Study
Western-style #diet impedes colonization and clearance of #Citrobacter rodentium
Western-style diet (WSD), which is high in fat and low in fiber, lacks nutrients to support gut microbiota. Consequently, WSD reduces microbiota density and promotes microbiota encroachment, potentially influencing colonization resistance, immune system readiness, and thus host defense against pathogenic bacteria. Here we examined the impact of WSD on infection and colitis in response to… Continue reading Western-style #diet impedes colonization and clearance of #Citrobacter rodentium
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