BackgroundWhether red meat consumption is associated with higher inflammation or confounded by increased adiposity remains unclear. Plasma metabolites capture the effects of diet after food is processed, digested, and absorbed, and correlate with markers of inflammation, so they can help clarify diet-health relationships.ObjectiveTo identify whether any metabolites associated with red meat intake are also associated… Continue reading Untargeted metabolomic analysis investigating links between unprocessed red #meat intake and markers of #inflammation
Effect of aerobic #exercise on #erectile function: systematic review and meta-analysis of randomized controlled trials
The health benefits of regular aerobic exercise are well established, although there is limited high-quality evidence regarding its impact on erectile function.AimTo determine the effect of aerobic exercise on erectile function in men and to identify factors that may influence this effect.MethodsThis systematic review and meta-analysis included randomized controlled trials that evaluated the effects of… Continue reading Effect of aerobic #exercise on #erectile function: systematic review and meta-analysis of randomized controlled trials
The endocannabinoid N-arachidonoyl dopamine is critical for #hyperalgesia induced by chronic #sleep disruption
Chronic pain is highly prevalent and is linked to a broad range of comorbidities, including sleep disorders. Epidemiological and clinical evidence suggests that chronic sleep disruption (CSD) leads to heightened pain sensitivity, referred to as CSD-induced hyperalgesia. However, the underlying mechanisms are unclear. The thalamic reticular nucleus (TRN) has unique integrative functions in sensory processing,… Continue reading The endocannabinoid N-arachidonoyl dopamine is critical for #hyperalgesia induced by chronic #sleep disruption
Ultra-processed #foods and #cardiometabolic health: public health policies to reduce consumption cannot wait
Incomplete understanding of the multiple mechanisms underlying the link between ultra-processed foods and cardiometabolic health should not be an excuse for inaction argue Mathilde Touvier and colleaguesThe effect of diet on health has historically been considered from a nutrient based perspective—for example, excess total fat, saturated fat, dietary cholesterol, calories, sugar, or salt and lack of… Continue reading Ultra-processed #foods and #cardiometabolic health: public health policies to reduce consumption cannot wait
Use of #sugar in #coffee and #tea and long-term risk of #mortality in older adult Danish men: 32 years of follow-up from a prospective cohort study
Tea and coffee are the most consumed beverages worldwide and very often sweetened with sugar. However, the association between the use of sugar in tea or coffee and adverse events is currently unclear.ObjectivesTo investigate the association between the addition of sugar to coffee or tea, and the risk of all-cause mortality, cardiovascular mortality, cancer mortality… Continue reading Use of #sugar in #coffee and #tea and long-term risk of #mortality in older adult Danish men: 32 years of follow-up from a prospective cohort study
Association Between #Triglycerides and Risk of #Dementia in Community-Dwelling #Older Adults: A Prospective Cohort Study
Background and Objectives: It has been suggested that higher triglyceride levels were associated with a lower risk of Alzheimer's disease. This study aimed to examine the association of triglycerides with dementia and cognition change in community-dwelling older adults.Methods: This prospective longitudinal study used data from the ASPREE randomized trial of adults aged ≥65 years without dementia or… Continue reading Association Between #Triglycerides and Risk of #Dementia in Community-Dwelling #Older Adults: A Prospective Cohort Study
The #sex gap in #bladder cancer survival — a missing link in bladder #cancer care?
The differences in bladder cancer outcomes between the sexes has again been highlighted. Uncommon among cancers, bladder cancer outcomes are notably worse for women than for men. Furthermore, bladder cancer is three to four times more common among men than among women. Factors that might explain these sex differences include understanding the importance of haematuria… Continue reading The #sex gap in #bladder cancer survival — a missing link in bladder #cancer care?
#Proton pump inhibitors and #dementia: A nationwide population-based study
Proton pump inhibitors (PPIs) may increase dementia risk. However, it is currently unknown whether timing of exposure or age at dementia diagnosis influence the risk.METHODSWe assessed associations between cumulative PPI use and dementia at different ages in a nationwide Danish cohort of 1,983,785 individuals aged 60 to 75 years between 2000 and 2018.RESULTSDuring follow-up, there… Continue reading #Proton pump inhibitors and #dementia: A nationwide population-based study
In Global Conflict Zones, Hospitals and Doctors Are No Longer Spared
Over the last two decades, medical facilities and staff have become casualties of war more frequently, in violation of international law. The explosion at the Ahli Arab Hospital in Gaza City on Tuesday was the latest in a growing series of violent incidents involving medical facilities in conflict zones, which together have taken an enormous… Continue reading In Global Conflict Zones, Hospitals and Doctors Are No Longer Spared
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