..Accelerometer-measured number of steps per day and 3 step intensity measures (extended bout cadence, peak 30-minute cadence, and peak 1-minute cadence [steps/min]). Accelerometer data were based on measurements obtained during a 7-day period at baseline. .. A total of 4840 participants (mean age, 56.8 years; 2435 [54%] women; 1732 [36%] individuals with obesity) wore accelerometers… Continue reading Association of Daily #Step Count and Step Intensity With Mortality Among US Adults
Open Access Oral #glucocorticoids and incidence of #hypertension in people with chronic inflammatory diseases: a population-based cohort study
..Among 71 642 patients in the cohort, 24 896 (34.8%) developed hypertension during a median follow-up of 6.6 years. The incidence rate of hypertension was 46.7 (95% confidence interval [CI] 46.0–47.3) per 1000 person-years. Incidence rates increased with higher cumulative glucocorticoid prednisolone-equivalent dose, from 44.4 per 1000 person-years in periods of nonuse to 45.3 per… Continue reading Open Access Oral #glucocorticoids and incidence of #hypertension in people with chronic inflammatory diseases: a population-based cohort study
BrainAGE and regional volumetric analysis of a Buddhist monk: a longitudinal MRI case study
Yongey Mingyur Rinpoche (YMR) is a Tibetan Buddhist monk, and renowned meditation practitioner and teacher who has spent an extraordinary number of hours of his life meditating. The brain-aging profile of this expert meditator in comparison to a control population was examined using a machine learning framework, which estimates “brain-age” from brain imaging. YMR’s brain-aging… Continue reading BrainAGE and regional volumetric analysis of a Buddhist monk: a longitudinal MRI case study
Intratumoral accumulation of gut #microbiota facilitates CD47-based immunotherapy via STING signaling
..Using one defined anaerobic gut microbiota to track whether microbiota interact with host immunity, we observed that Bifidobacterium facilitates local anti-CD47 immunotherapy on tumor tissues through the capacity to accumulate within the tumor microenvironment. Systemic administration of Bifidobacterium leads to its accumulation within the tumor and converts the nonresponder mice into responders to anti-CD47 immunotherapy… Continue reading Intratumoral accumulation of gut #microbiota facilitates CD47-based immunotherapy via STING signaling
A Person Can Carry And Transmit #COVID-19 Without Showing Symptoms, Scientists Confirm
Chinese researchers have confirmed a case of asymptomatic transmission of the new coronavirus: A 20-year-old woman from Wuhan passed it to five of her family members but never got physically sick herself.. ..A report from the Chinese Centre for Disease Control and Prevention analysed records of all of China's reported cases of the virus from… Continue reading A Person Can Carry And Transmit #COVID-19 Without Showing Symptoms, Scientists Confirm
#Diet modulates brain network stability, a biomarker for brain #aging, in young adults
..One cohort was scanned under standard diet, overnight fasting, and ketogenic diet conditions. To isolate the impact of fuel type, an independent overnight fasted cohort was scanned before and after administration of a calorie-matched glucose and exogenous ketone ester (D-β-hydroxybutyrate) bolus. Across the life span, brain network destabilization correlated with decreased brain activity and cognitive… Continue reading #Diet modulates brain network stability, a biomarker for brain #aging, in young adults
How long can the #coronavirus live on surfaces, can I get COVID-19 twice, and every other question you might have about the pandemic
All the answers here. https://bit.ly/33kjrtD
Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe #COVID-19
We report the kinetics of immune responses in relation to clinical and virological features of a patient with mild-to-moderate coronavirus disease 2019 (COVID-19) that required hospitalization. Increased antibody-secreting cells (ASCs), follicular helper T cells (TFH cells), activated CD4+ T cells and CD8+ T cells and immunoglobulin M (IgM) and IgG antibodies that bound the COVID-19-causing… Continue reading Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe #COVID-19
Characteristics and Outcomes of 21 Critically Ill Patients With #COVID-19 in Washington State
..A total of 21 cases were included (mean age, 70 years [range, 43-92 years]; 52% male). Comorbidities were identified in 18 cases (86%), with chronic kidney disease and congestive heart failure being the most common. Initial symptoms included shortness of breath (76%), fever (52%), and cough (48%) (Table 1). The mean onset of symptoms prior… Continue reading Characteristics and Outcomes of 21 Critically Ill Patients With #COVID-19 in Washington State
2 Medical News 