.. During 2.3 years of follow-up, 19.1% (n = 97) of the men and 13.6% (n = 158) of the women developed incident hypertension. The adjusted odds ratios (ORs) (95% confidence intervals [CIs]) for obesity (BMI ≥30) were 3.49 (1.59–7.66) and 2.60 (1.48–4.55) for men and women, respectively. A 1-point increase in BMI was associated… Continue reading Joint Effects of #Body Mass Index and Waist Circumference on the Incidence of #Hypertension in a Community-Based Chinese Population
Potential Effects of #Coronaviruses on the #Cardiovascular System
Coronavirus disease 2019 can cause a viral pneumonia with additional extrapulmonary manifestations and complications. A large proportion of patients have underlying cardiovascular disease and/or cardiac risk factors. Factors associated with mortality include male sex, advanced age, and presence of comorbidities including hypertension, diabetes mellitus, cardiovascular diseases, and cerebrovascular diseases. Acute cardiac injury determined by elevated… Continue reading Potential Effects of #Coronaviruses on the #Cardiovascular System
Hours lying down per day, as a proxy for sedentary behaviour and risk of #diabetes in young and middle-aged adults in Norway: an 11-year follow-up of the HUNT study
..362 individuals (2.1%) developed diabetes during an average of 11-year follow-up. Individuals who reported lying down ≥9 hours/day had an adjusted OR of 1.35 (95% CI 1.01 to 1.80) for incident diabetes compared with those lying down 8 hours/day. Lying down ≤7 hours/day was not associated with the risk of diabetes. In analysis stratified by physical activity, the… Continue reading Hours lying down per day, as a proxy for sedentary behaviour and risk of #diabetes in young and middle-aged adults in Norway: an 11-year follow-up of the HUNT study
EMA advises continued use of medicines for #hypertension, heart or #kidney disease during COVID-19 pandemic
EMA is aware of recent media reports and publications which question whether some medicines, for instance angiotensin converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs, or sartan medicines), could worsen coronavirus disease (COVID-19). ACE inhibitors and ARBs are most commonly used for treating patients with high blood pressure, heart failure or kidney disease. It… Continue reading EMA advises continued use of medicines for #hypertension, heart or #kidney disease during COVID-19 pandemic
Protein Structure and Sequence Reanalysis of 2019-nCoV Genome Refutes Snakes as Its Intermediate Host and the Unique Similarity between Its Spike Protein Insertions and HIV-1
As the infection of 2019-nCoV #coronavirus is quickly developing into a global pneumonia epidemic, the careful analysis of its transmission and cellular mechanisms is sorely needed. In this Communication, we first analyzed two recent studies that concluded that snakes are the intermediate hosts of 2019-nCoV and that the 2019-nCoV spike protein insertions share a unique… Continue reading Protein Structure and Sequence Reanalysis of 2019-nCoV Genome Refutes Snakes as Its Intermediate Host and the Unique Similarity between Its Spike Protein Insertions and HIV-1
AAO-HNS: #Anosmia, Hyposmia, and #Dysgeusia Symptoms of #Coronavirus Disease
Anecdotal evidence is rapidly accumulating from sites around the world that anosmia and dysgeusia are significant symptoms associated with the COVID-19 pandemic. Anosmia, in particular, has been seen in patients ultimately testing positive for the coronavirus with no other symptoms. We propose that these symptoms be added to the list of screening tools for possible… Continue reading AAO-HNS: #Anosmia, Hyposmia, and #Dysgeusia Symptoms of #Coronavirus Disease
#Aspirin for primary prevention of cardiovascular disease, part 2
..ASPREE study suggests no benefit from aspirin in primary prevention ASPREE randomized 19,114 healthy people 70 or over (65 or over for African Americans and Hispanics) to receive either 100 milligrams of enteric-coated aspirin or placebo. After an average of almost five years, there was no significant difference in the rate of fatal coronary heart… Continue reading #Aspirin for primary prevention of cardiovascular disease, part 2
Factors Associated With #Mental Health Outcomes Among Health Care Workers Exposed to #Coronavirus Disease 2019
.. A total of 1257 of 1830 contacted individuals completed the survey, with a participation rate of 68.7%. A total of 813 (64.7%) were aged 26 to 40 years, and 964 (76.7%) were women. Of all participants, 764 (60.8%) were nurses, and 493 (39.2%) were physicians; 760 (60.5%) worked in hospitals in Wuhan, and 522… Continue reading Factors Associated With #Mental Health Outcomes Among Health Care Workers Exposed to #Coronavirus Disease 2019
The Effectiveness of Social #Distancing in Mitigating #COVID-19 Spread: a modelling analysis
..The application of all four social distancing interventions: school closure, workplace non-attendance, increased case isolation, and community contact reduction is highly effective in flattening the epidemic curve, reducing the maximum daily case numbers, and lengthening outbreak duration. These were also found to be effective even after 10 weeks delay from index case arrivals. The most… Continue reading The Effectiveness of Social #Distancing in Mitigating #COVID-19 Spread: a modelling analysis
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