...SARS-CoV-2 has the protean ability to cause myriad clinical manifestations, ranging from a complete lack of symptoms to pneumonia, acute respiratory distress syndrome, and death. Recent virologic, epidemiologic, and ecologic data have led to the hypothesis that facial masking may also reduce the severity of disease among people who do become infected.3 This possibility is… Continue reading Facial Masking for #Covid-19 — Potential for “#Variolation” as We Await a Vaccine
Use of #beta-blockers for #rosacea-associated facial erythema and flushing: A systematic review and update on proposed mode of action
Flushing and erythema are frequent skin symptoms in rosacea. Because their adequate treatment remains a clinical challenge, new treatment options are explored, such as oral β-blockers.. ..Nine studies evaluating the use of carvedilol, propranolol, nadolol, and β-blockers in general were included. Articles studying carvedilol and propranolol showed a large reduction of erythema and flushing during… Continue reading Use of #beta-blockers for #rosacea-associated facial erythema and flushing: A systematic review and update on proposed mode of action
Vitamin #D sufficiency, a serum 25-hydroxyvitamin D at least 30 ng/mL reduced risk for adverse clinical outcomes in patients with #COVID-19 infection
To investigate the association between serum 25-hydroxyvitamin D levels and its effect on adverse clinical outcomes, and parameters of immune function and mortality due to a SARS-CoV-2 infection.. ..Based on CDC criteria, among our study patients, 74% had severe COVID-19 infection and 32.8% were vitamin D sufficient. After adjusting for confounding factors, there was a… Continue reading Vitamin #D sufficiency, a serum 25-hydroxyvitamin D at least 30 ng/mL reduced risk for adverse clinical outcomes in patients with #COVID-19 infection
Relationship Among Sensory Over-Responsivity, Problem Behaviors, and #Anxiety in Emerging Adults with #Autism Spectrum Disorder
Despite the highly prevailing rate of sensory over-responsivity, problem behaviors, and anxiety among emerging adults with autism spectrum disorder (ASD), little is known about the nature of their experiences. While previous studies have indicated potential relationships among these conditions, their connections still need to be clarified. This study aimed to examine the relationships between sensory… Continue reading Relationship Among Sensory Over-Responsivity, Problem Behaviors, and #Anxiety in Emerging Adults with #Autism Spectrum Disorder
#Language comprehension in the social #brain: Electrophysiological brain signals of social presence effects during syntactic and semantic sentence processing
Although, evolutionarily, language emerged predominantly for social purposes, much has yet to be uncovered regarding how language processing is affected by social context. Social presence research studies the ways in which the presence of a conspecific affects processing, but has yet to be thoroughly applied to language processes. The principal aim of this study was… Continue reading #Language comprehension in the social #brain: Electrophysiological brain signals of social presence effects during syntactic and semantic sentence processing
Low #carbohydrate diet and all cause and cause-specific #mortality
Evidence is limited regarding the association between low-carbohydrate diet (LCD) score and mortality among Asians, a population that consumes a large amount of carbohydrates.. ..A U-shaped association was observed between LCD score and total mortality: the multivariable-adjusted hazard ratios (HRs) (95% CI) of total mortality for lowest through highest scores were 1.00, 0.95 (0.91, 1.01),… Continue reading Low #carbohydrate diet and all cause and cause-specific #mortality
#Dapagliflozin in Patients with Chronic #Kidney Disease
Patients with chronic kidney disease have a high risk of adverse kidney and cardiovascular outcomes. The effect of dapagliflozin in patients with chronic kidney disease, with or without type 2 diabetes, is not known.. ..The independent data monitoring committee recommended stopping the trial because of efficacy. Over a median of 2.4 years, a primary outcome… Continue reading #Dapagliflozin in Patients with Chronic #Kidney Disease
Trends in #Adiposity and #Food Insecurity Among US Adults
..Food insecurity is a core indicator of nutritional status and “exists whenever the availability of nutritionally adequate and safe foods or the ability to acquire acceptable foods in socially acceptable ways is limited or uncertain.” ..Main Outcomes and Measures The primary outcome was food insecurity. Data on BMI (calculated as weight in kilograms divided by… Continue reading Trends in #Adiposity and #Food Insecurity Among US Adults
#Meningeal γδ T cells regulate #anxiety-like behavior via IL-17a signaling in neurons
Interleukin (IL)-17a has been highly conserved during evolution of the vertebrate immune system and widely studied in contexts of infection and autoimmunity. Studies suggest that IL-17a promotes behavioral changes in experimental models of autism and aggregation behavior in worms. Here, through a cellular and molecular characterization of meningeal γδ17 T cells, we defined the nearest… Continue reading #Meningeal γδ T cells regulate #anxiety-like behavior via IL-17a signaling in neurons
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