Knowledge of the risk of recurrence after recovery from major depressive disorder (MDD) in the general population is scarce. Method Data were derived from 687 subjects in the general population with a lifetime DSM-III-R diagnosis of MDD but without a current major depressive episode (MDE) or dysthymia. Participants had to be at least 6 months… Continue reading Recurrence of major #depressive disorder and its predictors in the general population: results from The Netherlands Mental Health Survey and Incidence Study (NEMESIS)
#Benzophenone-3 promotion of mammary tumorigenesis is diet-dependent
Benzophenone-3 is a putative endocrine disrupting chemical and common ingredient in sunscreens. The potential of endocrine disrupting chemicals to act as agonists or antagonists in critical hormonally regulated processes, such as mammary gland development and mammary tumorigenesis, demands evaluation of its potential in promoting breast cancer. This study identifies the effects of BP-3 on mammary… Continue reading #Benzophenone-3 promotion of mammary tumorigenesis is diet-dependent
#Coffee consumption and risk of #prostate cancer: a systematic review and meta-analysis
To conduct a systematic review with meta-analysis of cohort studies to evaluate the association of coffee consumption with the risk of prostate cancer.. ..Sixteen prospective cohort studies were finally included, with 57 732 cases of prostate cancer and 1 081 586 total cohort members. Higher coffee consumption was significantly associated with a lower risk of prostate cancer. Compared… Continue reading #Coffee consumption and risk of #prostate cancer: a systematic review and meta-analysis
Progression of #Myopia in School-Aged Children After #COVID-19 Home Confinement
Time spent in outdoor activities has decreased owing to home confinement for the coronavirus disease 2019 (COVID-19) pandemic. Concerns have been raised about whether home confinement may have worsened the burden of myopia owing to substantially decreased time spent outdoors and increased screen time at home.. .. Of the 123 535 children included in the study,… Continue reading Progression of #Myopia in School-Aged Children After #COVID-19 Home Confinement
Physiologically increased total #bilirubin is associated with reduced risk of first #myocardial infarction: A meta-analysis and dose-response analysis
Bilirubin has potential predictive and prognostic value for myocardial infarction (MI), but the clinical evidence remains controversial. We performed this meta-analysis to systematically quantify the relationships between circulating bilirubin levels and the incidence of MI and post-MI adverse events. We searched the PubMed, Cochrane Library, Embase, and Web of Science databases for ad-hoc studies, published… Continue reading Physiologically increased total #bilirubin is associated with reduced risk of first #myocardial infarction: A meta-analysis and dose-response analysis
Evaluating the impact of a time orientation intervention on #well-being during the #COVID-19 lockdown: past, present or future?
Lockdown policies brought on by the COVID-19 pandemic pose a threat to well-being. This study examined the effectiveness of three positive psychology interventions, with different time-orientations, on well-being as well as predictors of well-being during lockdown. Participants (n= 216) completed measures of lockdown characteristics, attachment orientation, and emotion regulation, were then randomly allocated to one… Continue reading Evaluating the impact of a time orientation intervention on #well-being during the #COVID-19 lockdown: past, present or future?
Clinical Outcomes Associated With Left #Atrial Appendage Occlusion Versus Direct Oral #Anticoagulation in Atrial #Fibrillation
This study sought to investigate clinical outcomes associated with left atrial appendage occlusion (LAAO) versus direct oral anticoagulants (DOACs) in patients with high-risk atrial fibrillation (AF).. ..Patients with AF enrolled in the Amulet Observational Registry (n = 1,088) who had successful LAAO with the Amplatzer Amulet device (n = 1,078) were compared with a propensity… Continue reading Clinical Outcomes Associated With Left #Atrial Appendage Occlusion Versus Direct Oral #Anticoagulation in Atrial #Fibrillation
#Cancer Statistics, 2021
Each year, the American Cancer Society estimates the numbers of new cancer cases and deaths in the United States and compiles the most recent data on population‐based cancer occurrence. Incidence data (through 2017) were collected by the Surveillance, Epidemiology, and End Results Program; the National Program of Cancer Registries; and the North American Association of… Continue reading #Cancer Statistics, 2021
Impact of Inappropriate #Antibiotic Therapy in Vancomycin-Resistant #Enterococcus Bacteremia
Vancomycin-resistant Enterococcus (VRE) bacteremia has significant morbidity and mortality. Empiric antibiotic regimens for treating patients with risk factors for multidrug-resistant organisms may not have medications directed at treating VRE.. ..The inpatient, 30-day, and 1-year mortality rates from VRE bacteremia were 23%, 31%, and 59%, respectively. Only 19% patients were discharged home. Inappropriate antibiotics were prescribed… Continue reading Impact of Inappropriate #Antibiotic Therapy in Vancomycin-Resistant #Enterococcus Bacteremia
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